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The accurate treatment of electron correlation in extended molecular systems remains computationally challenging using classical electronic structure methods. Hybrid quantum-classical algorithms offer a potential route to overcome these…

Reduced density matrices (RDMs) are fundamental in quantum information processing, allowing the computation of local observables, such as energy and correlation functions, without the exponential complexity of fully characterizing quantum…

Quantum Physics · Physics 2025-06-13 Zherui Jerry Wang , David Dechant , Yash J. Patel , Jordi Tura

The quantum computation of electronic energies can break the curse of dimensionality that plagues many-particle quantum mechanics. It is for this reason that a universal quantum computer has the potential to fundamentally change…

An alternative method is introduced to solve a simple two-dimensional models describing vibrational excitation and dissociation processes during the electron-molecule collisions. The model works with one electronic and one nuclear degree of…

Chemical Physics · Physics 2018-12-19 Roman Čurík , Dávid Hvizdoš , Chris H. Greene

Reduced density matrices are central to describing observables in many-body quantum systems. In electronic structure theory, the two-particle reduced density matrix (2-RDM) suffices to determine the energy and other key properties. Recent…

For many-electron systems, the second-order reduced density matrix (2-RDM) provides sufficient information for characterizing their properties of interests in physics and chemistry, ranging from total energy, magnetism, quantum correlation…

Quantum Physics · Physics 2021-05-12 Yimin Li

The Transformer model, renowned for its powerful attention mechanism, has achieved state-of-the-art performance in various artificial intelligence tasks but faces challenges such as high computational cost and memory usage. Researchers are…

Quantum Physics · Physics 2026-03-24 Yuichi Kamata , Quoc Hoan Tran , Yasuhiro Endo , Hirotaka Oshima

Quantum machine learning has emerged as a potential practical application of near-term quantum devices. In this work, we study a two-layer hybrid classical-quantum classifier in which a first layer of quantum stochastic neurons implementing…

Quantum Physics · Physics 2022-05-11 Ivana Nikoloska , Osvaldo Simeone

Excited-state properties of highly correlated systems are key to understanding photosynthesis, luminescence, and the development of novel optical materials, but accurately capturing their interactions is computationally costly. We present…

Quantum Physics · Physics 2024-08-21 Irma Avdic , David A. Mazziotti

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Quantum computing brings a promise of new approaches into computational quantum chemistry. While universal, fault-tolerant quantum computers are still not available, we want to utilize today's noisy quantum processors. One of their flagship…

Accurate amine property prediction is essential for optimizing CO2 capture efficiency in post-combustion processes. Quantum machine learning (QML) can enhance predictive modeling by leveraging superposition, entanglement, and interference…

Quantum Physics · Physics 2025-06-24 Hyein Cho , Jeonghoon Kim , Hocheol Lim

We ask how much energy is required to weakly simulate an $n$-qubit quantum circuit (i.e., produce samples from its output distribution) by a unitary circuit in a hybrid qubit-oscillator model. The latter consists of a certain number of…

Quantum Physics · Physics 2025-09-24 Lukas Brenner , Beatriz Dias , Robert Koenig

Accurately predicting response properties of molecules such as the dynamic polarizability and hyperpolarizability using quantum mechanics has been a long-standing challenge with widespread applications in material and drug design. Classical…

Chemical Physics · Physics 2020-09-01 Xiaoxia Cai , Wei-Hai Fang , Heng Fan , Zhendong Li

Efficient representations of the Hamiltonian such as double factorization drastically reduce circuit depth or number of repetitions in error corrected and noisy intermediate scale quantum (NISQ) algorithms for chemistry. We report a…

We present a hybrid quantum-classical algorithm to simulate thermal states of a classical Hamiltonians on a quantum computer. Our scheme employs a sequence of locally controlled rotations, building up the desired state by adding qubits one…

Quantum Physics · Physics 2015-03-17 Man-Hong Yung , Daniel Nagaj , James D. Whitfield , Alán Aspuru-Guzik

Variational calculation of the ground state energy and its properties using the second-order reduced density matrix (2-RDM) is a promising approach for quantum chemistry. A major obstacle with this approach is that the $N$-representability…

Chemical Physics · Physics 2011-08-30 Maho Nakata

Hybrid Quantum-Classical Machine Learning (ML) is an emerging field, amalgamating the strengths of both classical neural networks and quantum variational circuits on the current noisy intermediate-scale quantum devices. This paper performs…

In this paper, we propose a novel Hadamard Transform (HT)-based neural network layer for hybrid quantum-classical computing. It implements the regular convolutional layers in the Hadamard transform domain. The idea is based on the HT…

Computer Vision and Pattern Recognition · Computer Science 2024-02-26 Hongyi Pan , Xin Zhu , Salih Atici , Ahmet Enis Cetin

Quantum computing has emerged as a promising technology for solving problems that are intractable for classical computers. In this study, we introduce quantum computing and implement the Variational Quantum Eigensolver (VQE) algorithm using…

Quantum Physics · Physics 2023-05-12 Maomin Qing , Wei Xie
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