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Machine learning is a prevalent approach to tame the complexity of design space exploration for domain-specific architectures. Using ML for design space exploration poses challenges. First, it's not straightforward to identify the suitable…

Cloud Computing researches involve a tremendous amount of entities such as users, applications, and virtual machines. Due to the limited access and often variable availability of such resources, researchers have their prototypes tested…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-01-18 Pradeeban Kathiravelu

Hardware accelerators, such as those based on GPUs and FPGAs, offer an excellent opportunity to efficiently parallelize functionalities. Recently, modern embedded platforms started being equipped with such accelerators, resulting in a…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-16 Daniel Casini , Paolo Pazzaglia , Alessandro Biondi , Marco Di Natale

With the increasing popularity of accelerator technologies (e.g., GPUs and TPUs) and the emergence of domain-specific computing via ASICs and FPGA, the matter of heterogeneity and understanding its ramifications on the performance has…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-21 Ali Mokhtari , Drake Rawls , Tony Huynh , Jeremiah Green , Mohsen Amini Salehi

Neuromorphic-style inference only works well if limited hardware resources are maximized properly, e.g. accuracy continues to scale with parameters and complexity in the face of potential disturbance. In this work, we use realistic crossbar…

Neural and Evolutionary Computing · Computer Science 2020-03-24 Christopher H. Bennett , Ryan Dellana , T. Patrick Xiao , Ben Feinberg , Sapan Agarwal , Suma Cardwell , Matthew J. Marinella , William Severa , Brad Aimone

Compound AI applications, composed from interactions between Large Language Models (LLMs), Machine Learning (ML) models, external tools and data sources are quickly becoming an integral workload in datacenters. Their diverse sub-components…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Paramuth Samuthrsindh , Angel Cervantes , Varun Gohil , Gohar Irfan Chaudhry , Christina Delimitrou , Adam Belay

Reinforcement learning (RL), large language models (LLMs), and vision-language models (VLMs) have been widely studied in isolation. However, existing infrastructure lacks the ability to deploy agents from different decision-making paradigms…

Despite the rapid progress of Vision-Language Models (VLMs), their capabilities are inadequately assessed by existing benchmarks, which are predominantly English-centric, feature simplistic layouts, and support limited tasks. Consequently,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Ketong Chen , Yuhao Chen , Yang Xue

The stochastic simulation of biological systems is an increasingly popular technique in bioinformatics. It often is an enlightening technique, which may however result in being computational expensive. We discuss the main opportunities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Marco Aldinucci , Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Massimo Torquati , Angelo Troina

MiMiC is a framework for performing multiscale simulations in which loosely coupled external programs describe individual subsystems at different resolutions and levels of theory. To make it highly efficient and flexible, we adopt an…

The proliferation of heterogeneous chip multiprocessors in recent years has reached unprecedented levels. Traditional homogeneous platforms have shown fundamental limitations when it comes to enabling high-performance yet-ultra-low-power…

Image processing applications are common in every field of our daily life. However, most of them are very complex and contain several tasks with different complexities which result in varying requirements for computing architectures.…

Computer Vision and Pattern Recognition · Computer Science 2015-02-27 Christian Hartmann , Anna Yupatova , Marc Reichenbach , Dietmar Fey , Reinhard German

Molecular Dynamics (MD) simulations are ubiquitous in cutting-edge physio-chemical research. They provide critical insights into how a physical system evolves over time given a model of interatomic interactions. Understanding a system's…

Computational Physics · Physics 2023-09-06 Rostyslav Hnatyshyn , Jieqiong Zhao , Danny Perez , James Ahrens , Ross Maciejewski

There are many science applications that require scalable task-level parallelism and support for flexible execution and coupling of ensembles of simulations. Most high-performance system software and middleware, however, are designed to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-29 Vivekanandan Balasubramanian , Antons Treikalis , Ole Weidner , Shantenu Jha

Heterogeneous computers integrate general-purpose host processors with domain-specific accelerators to combine versatility with efficiency and high performance. To realize the full potential of heterogeneous computers, however, many…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-12 Andreas Kurth , Björn Forsberg , Luca Benini

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

High-Level Synthesis (HLS) enables rapid prototyping of complex hardware designs by translating C or C++ code to low-level RTL code. However, the testing and evaluation of HLS designs still typically rely on slow RTL-level simulators that…

Performance · Computer Science 2024-04-18 Rishov Sarkar , Rachel Paul , Cong Hao

Computer architecture simulation is essential for evaluating new designs without the need for costly tapeout. The community has developed dozens of valuable simulators that have enabled significant architectural advances. However, using and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-01 Sabila Al Jannat , Ying Li , Mengyang He , Xuzhong Wang , Huizhi Zhao , Jingxiang Sun , Daoxuan Xu , Enze Xu , Yifan Sun

While discrete-event simulators are essential tools for architecture research, design, and development, their practicality is limited by an extremely long time-to-solution for realistic applications under investigation. This work describes…

Hardware Architecture · Computer Science 2022-04-07 Lingda Li , Santosh Pandey , Thomas Flynn , Hang Liu , Noel Wheeler , Adolfy Hoisie

GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest…

Computational Engineering, Finance, and Science · Computer Science 2015-06-03 Páll Szilárd , Mark James Abraham , Carsten Kutzner , Berk Hess , Erik Lindahl