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Identifying the nodes that have the potential to influence the state of a network is a relevant question for many complex systems. In many applications it is often essential to test the ability of an individual node to control a specific…

Molecular Networks · Quantitative Biology 2020-12-08 Giulia Bassignana , Jennifer Fransson , Vincent Henry , Olivier Colliot , Violetta Zujovic , Fabrizio De Vico Fallani

Elucidating the architecture and dynamics of large scale genetic regulatory networks of cells is an important goal in systems biology. We study the system level dynamical properties of the genetic network of Escherichia coli that regulates…

Molecular Networks · Quantitative Biology 2008-02-29 Areejit Samal , Sanjay Jain

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

In automata networks, it is well known that the way entities update their states over time has a major impact on their dynamics. In particular, depending on the chosen update schedule, the underlying dynamical systems may exhibit more or…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Sylvain Sené

Boolean threshold networks have recently been proposed as useful tools to model the dynamics of genetic regulatory networks, and have been successfully applied to describe the cell cycles of \textit{S. cerevisiae} and \textit{S. pombe}.…

Chaotic Dynamics · Physics 2010-11-18 Jorge G. T. Zañudo , Maximino Aldana , Gustavo Martínez-Mekler

Previous work showed that the collective activity of large neuronal networks can be tamed to remain near its critical point by a feedback control that maximizes the temporal correlations of the mean-field fluctuations. Since such…

Neurons and Cognition · Quantitative Biology 2023-03-29 Juliane T. Moraes , Eyisto J. Aguilar Trejo , Sabrina Camargo , Silvio C. Ferreira , Dante R. Chialvo

A properly designed controller can help improve the quality of experimental measurements or force a dynamical system to follow a completely new time-evolution path. Recent developments in deep reinforcement learning have made steep advances…

Statistical Mechanics · Physics 2025-02-26 Ruslan Mukhamadiarov

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

This study proposes a novel artificial intelligence (AI) driven flight computer, integrating an online free-retraining-prediction model, a swarm control, and an obstacle avoidance strategy, to track dynamic targets using a distributed drone…

Robotics · Computer Science 2024-10-16 Lucas Page

We present new applications of parity inversion and time-reversal to the emergence of complex behavior from simple dynamical rules in stochastic discrete models. Our parity-based encoding of causal relationships and time-reversal…

Adaptation and Self-Organizing Systems · Physics 2021-07-20 Jordan C. Rozum , Jorge Gómez Tejeda Zañudo , Xiao Gan , Dávid Deritei , Réka Albert

Membrane computing and P systems are a paradigm of massively parallel natural computing introduced by Gheorghe P\u{a}un in 1999, inspired by the structure of the living cell and by its biochemical reactions. In spite of this explicit…

Formal Languages and Automata Theory · Computer Science 2022-09-01 Artiom Alhazov , Rudolf Freund , Sergiu Ivanov

Recently, the use of bio-inspired learning techniques such as Hebbian learning and its closely-related Spike-Timing-Dependent Plasticity (STDP) variant have drawn significant attention for the design of compute-efficient AI systems that can…

Neural and Evolutionary Computing · Computer Science 2024-11-19 Ali Safa

Biological networks are pivotal in deciphering the complexity and functionality of biological systems. Causal inference, which focuses on determining the directionality and strength of interactions between variables rather than merely…

Molecular Networks · Quantitative Biology 2025-11-05 Hongyang Jiang , Yuezhu Wang , Ke Feng , Chaoyi Yin , Yi Chang , Huiyan Sun

Stochastic resetting, the procedure of stopping and re-initializing random processes, has recently emerged as a powerful tool for accelerating processes ranging from queuing systems to molecular simulations. However, its usefulness is…

Statistical Mechanics · Physics 2025-03-18 Tommer D. Keidar , Ofir Blumer , Barak Hirshberg , Shlomi Reuveni

Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory…

Soft Condensed Matter · Physics 2009-11-07 Sergei Maslov , Kim Sneppen

This paper focuses on proposing a general control framework for large-scale Boolean networks (\texttt{BNs}). Only by the network structure, the concept of structural controllability for \texttt{BNs} is formalized. A necessary and sufficient…

Systems and Control · Electrical Eng. & Systems 2021-05-27 Shiyong Zhu , Jianquan Lu , Shun-ichi Azuma , Wei Xing Zheng

This paper presents a real-time simulation involving ''protozoan-like'' cells that evolve by natural selection in a physical 2D ecosystem. Selection pressure is exerted via the requirements to collect mass and energy from the surroundings…

Neural and Evolutionary Computing · Computer Science 2023-05-23 Dylan Cope

The control of chaotic systems implies inducing an unpredictable system to follow a desired trajectory using the smallest "force". In low-dimensional continuous systems, one method is that of reconstructing the tangent space, so that the…

Cellular Automata and Lattice Gases · Physics 2009-02-03 Franco Bagnoli , Raul Rechtman

Boolean Networks and their dynamics are of great interest as abstract modeling schemes in various disciplines, ranging from biology to computer science. Whereas parallel update schemes have been studied extensively in past years, the level…

Statistical Mechanics · Physics 2007-07-19 Hamed Mahmoudi , Andrea Pagnani , Martin Weigt , Riccardo Zecchina

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein