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Reaction networks can display a wide array of dynamics. However, it is possible for different reaction networks to display the same dynamics. This phenomenon is called dynamical equivalence and makes network identification a hard problem to…

Dynamical Systems · Mathematics 2022-05-03 Abhishek Deshpande

We investigate the possibility that for any given reaction rate vector $k$ associated with a network $G$, there exists another network $G'$ with a corresponding reaction rate vector that reproduces the mass-action dynamics generated by…

Dynamical Systems · Mathematics 2024-09-10 Samay Kothari , Jiaxin Jin , Abhishek Deshpande

We show that there exists endotactic and strongly endotactic dynamical systems that are not weakly reversible and possess infinitely many steady states. We provide a few examples in two dimensions and an example in three dimensions that…

Dynamical Systems · Mathematics 2023-03-16 Samay Kothari , Abhishek Deshpande

Reaction networks are mainly used to model the time-evolution of molecules of interacting chemical species. Stochastic models are typically used when the counts of the molecules are low, whereas deterministic models are used when the counts…

Probability · Mathematics 2019-10-04 David Anderson , Daniele Cappelletti , Jinsu Kim , Tung Nguyen

An important dynamical property of biological interaction networks is persistence, which intuitively means that "no species goes extinct". It has been conjectured that dynamical system models of weakly reversible networks (i.e., networks…

Dynamical Systems · Mathematics 2019-06-21 Gheorghe Craciun , Abhishek Deshpande

We establish a new relationship between monotonicity and contractivity and use this connection to describe a new general class of weakly contractive reaction networks. The new class is characterized by the stoichiometry matrix of the…

Dynamical Systems · Mathematics 2025-06-24 Alon Duvall , M. Ali Al-Radhawi , Dhruv D. Jatkar , Eduardo Sontag

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

Dynamical Systems · Mathematics 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

It has been known for nearly a decade that deterministically modeled reaction networks that are weakly reversible and consist of a single linkage class have trajectories that are bounded from both above and below by positive constants (so…

Probability · Mathematics 2020-01-17 David F. Anderson , Daniele Cappelletti , Jinsu Kim

Given a dynamical system with polynomial right-hand side, can it be generated by a reaction network that possesses certain properties? This question is important because some network properties may guarantee specific dynamical properties,…

Dynamical Systems · Mathematics 2023-03-17 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

We describe a large class of chemical reaction networks, those endowed with a subtle structural property called concordance. We show that the class of concordant networks coincides precisely with the class of networks which, when taken with…

Molecular Networks · Quantitative Biology 2011-09-15 Guy Shinar , Martin Feinberg

A reaction network together with a choice of rate constants uniquely gives rise to a system of differential equations, according to the law of mass-action kinetics. On the other hand, different networks can generate the same dynamical…

Dynamical Systems · Mathematics 2021-05-18 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

Interactions between units in phyical, biological, technological, and social systems usually give rise to intrincate networks with non-trivial structure, which critically affects the dynamics and properties of the system. The focus of most…

Data Analysis, Statistics and Probability · Physics 2007-05-23 R. Guimera , M. Sales-Pardo , L. A. N. Amaral

Under suitable assumptions, the dynamic behaviour of a chemical reaction network is governed by an autonomous set of polynomial ordinary differential equations over continuous variables representing the concentrations of the reactant…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel

In this paper, we study extinction in dynamical systems generated by reaction networks. We introduce two notions: weak extinction and strong extinction, and relate them to the structure of the underlying network through Lyapunov functions…

Dynamical Systems · Mathematics 2026-01-14 Pranav Agarwal , Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

We characterize completely the capacity for (nondegenerate) multistationarity of mass action reaction networks with one-dimensional stoichiometric subspace in terms of reaction structure. Specifically, we show that networks with two or more…

Dynamical Systems · Mathematics 2022-08-15 Casian Pantea , Galyna Voitiuk

The induced kinetic differential equation of a reaction network endowed with mass action type kinetics is a system of polynomial differential equations. The problem studied here is: Given a polynomial differential equation, is it possible…

Dynamical Systems · Mathematics 2019-09-10 G. Craciun , M. D. Johnston , G. Szederkényi , E. Tonello , J. Tóth , P. Y. Yu

Chemical reaction networks (CRNs) are directed graphs with reactant or product complexes as vertices, and reactions as arcs. A CRN is weakly reversible if each of its connected components is strongly connected. Weakly reversible networks…

Percolation, the formation of a macroscopic connected component, is a key feature in the description of complex networks. The dynamical properties of a variety of systems can be understood in terms of percolation, including the robustness…

Statistical Mechanics · Physics 2013-06-24 Shane Squires , Katherine Sytwu , Diego Alcala , Thomas Antonsen , Edward Ott , Michelle Girvan

All types of networks arise as intricate combinations of dyadic building blocks formed by pairs of vertices. In directed networks, the dyadic patterns are entirely determined by reciprocity, i.e. the tendency to form, or to avoid, mutual…

Data Analysis, Statistics and Probability · Physics 2014-01-14 Tiziano Squartini , Francesco Picciolo , Franco Ruzzenenti , Diego Garlaschelli

We study the evolution of a random weighted network with complex nonlinear dynamics at each node, whose activity may cease as a result of interactions with other nodes. Starting from a knowledge of the micro-level behaviour at each node, we…

Statistical Mechanics · Physics 2007-05-23 Sitabhra Sinha , Sudeshna Sinha
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