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This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

Agent-based modeling (ABM) has emerged as a powerful tool in social policy-making and socio-economics, offering a flexible and dynamic approach to understanding and simulating complex systems. While traditional analytic methods may be less…

Multiagent Systems · Computer Science 2025-04-03 Shayan Firouzian Haji

In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…

Populations and Evolution · Quantitative Biology 2021-01-01 Reza Sameni

The recent history of respiratory pathogen epidemics, including those caused by influenza and SARS-CoV-2, has highlighted the urgent need for advanced modeling approaches that can accurately capture heterogeneous disease dynamics and…

Populations and Evolution · Quantitative Biology 2025-04-07 Prescott C. Alexander , Thomas J. Harris , Joy Kitson , Joseph V. Tuccillo , Sara Y. Del Valle , Timothy C. Germann

Today's most troublesome population health challenges are often driven by social and environmental determinants, which are difficult to model using traditional epidemiological methods. We agree with those who have argued for the wider…

Multiagent Systems · Computer Science 2020-02-07 Eric Silverman , Umberto Gostoli , Stefano Picascia , Jonatan Almagor , Mark McCann , Richard Shaw , Claudio Angione

This paper introduces a microscopic approach to model epidemics, which can explicitly consider the consequences of individual's decisions on the spread of the disease. We first formulate a microscopic multi-agent epidemic model where every…

Multiagent Systems · Computer Science 2020-04-28 Changliu Liu

Plasmodium vivax is one of the most geographically widespread malaria parasites in the world due to its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse…

Human mobility forms the backbone of contact patterns through which infectious diseases propagate, fundamentally shaping the spatio-temporal dynamics of epidemics and pandemics. While traditional models are often based on the assumption…

Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…

Physics and Society · Physics 2014-07-23 Lara Goscé , David A W Barton , Anders Johansson

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

System dynamics and agent based simulation models can both be used to model and understand interactions of entities within a population. Our modeling work presented here is concerned with understanding the suitability of the different types…

Computational Engineering, Finance, and Science · Computer Science 2013-06-27 Grazziela P. Figueredo , Uwe Aickelin

Automated malaria diagnosis is a difficult but high-value target for machine learning (ML), and effective algorithms could save many thousands of children's lives. However, current ML efforts largely neglect crucial use case constraints and…

Machine Learning · Computer Science 2023-07-06 Charles B. Delahunt , Noni Gachuhi , Matthew P. Horning

Human cognitive responses, behavioral responses, and disease dynamics co-evolve over the course of any disease outbreak, and can result in complex feedbacks. We present a dynamic agent-based model that explicitly couples the spread of…

We study the impact of contact heterogeneity on epidemic dynamics. A system characterized by multiple susceptible populations is considered. The description of the spread of an infectious disease is obtained through the study of a system of…

Physics and Society · Physics 2021-11-11 Andrea Medaglia , Mattia Zanella

In this paper we propose some mathematical models for the transmission of dengue using a system of reaction-diffusion equations. The mosquitoes are divided into infected, uninfected and aquatic subpopulations, while the humans, which are…

Analysis of PDEs · Mathematics 2018-11-21 Felipo Bacani , Stylianos Dimas , Igor Leite Freire , Norberto Anibal Maidana , Mariano Torrisi

This paper gives an introduction to rule-based modelling applied to topics in infectious diseases. Rule-based models generalise reaction-based models with reagents that have internal state and may be bound together to form complexes, as in…

Populations and Evolution · Quantitative Biology 2021-08-10 William Waites , Matteo Cavaliere , David Manheim , Jasmina Panovska-Griffiths , Vincent Danos

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

Accounting for population age structure and age-specific contact patterns is crucial for accurate modelling of human infectious disease dynamics and impact. A common approach is to use contact matrices, which estimate the number of contacts…

Populations and Evolution · Quantitative Biology 2025-08-25 Caleb Sullivan , Pubudu Senanayake , Michael J. Plank

Mathematical modelling can help to explain the nature and dynamics of infection transmissions, as well as support a policy for implementing those strategies that are most likely to bring public health and economic benefits. The paper…

Optimization and Control · Mathematics 2015-09-01 Roman Denysiuk , Cristiana J. Silva , Delfim F. M. Torres

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho