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Severity assessment of Parkinson's disease (PD) using wearable sensors offers an effective, objective basis for clinical management. However, general-purpose time series models often lack pathological specificity in feature extraction,…

Machine Learning · Computer Science 2025-10-14 Weiming Zhao , Xulong Wang , Jun Qi , Yun Yang , Po Yang

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

Quantitative Methods · Quantitative Biology 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Stable gait generation is a crucial problem for legged robot locomotion as this impacts other critical performance factors such as, e.g. mobility over an uneven terrain and power consumption. Gait generation stability results from the…

Robotics · Computer Science 2023-07-18 Vyacheslav Kovalev , Anna Shkromada , Henni Ouerdane , Pavel Osinenko

In this paper, we envision a web-based framework that can help anyone, anywhere around the world record a short speech task, and analyze the recorded data to screen for Parkinson's disease (PD). We collected data from 726 unique…

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

Machine Learning · Computer Science 2026-04-21 Meheru Zannat

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. It is associated with an increased risk of stroke, heart failure, and other cardiovascular complications, but can be clinically silent. Passive AF monitoring with…

Machine Learning · Computer Science 2024-03-12 Zhicheng Guo , Cheng Ding , Duc H. Do , Amit Shah , Randall J. Lee , Xiao Hu , Cynthia Rudin

Current gait analysis faces challenges in various aspects, including limited and poorly labeled data within existing wearable electronics databases, difficulties in collecting patient data due to privacy concerns, and the inadequacy of the…

Signal Processing · Electrical Eng. & Systems 2026-01-05 Wenwen Zhang , Hao Zhang , Zenan Jiang , Amir Servati , Peyman Servati

We present InceptoFormer, a multi-signal neural framework designed for Parkinson's Disease (PD) severity evaluation via gait dynamics analysis. Our architecture introduces a 1D adaptation of the Inception model, which we refer to as…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Safwen Naimi , Arij Said , Wassim Bouachir , Guillaume-Alexandre Bilodeau

Human walking is a complex activity with a high level of cooperation and interaction between different systems in the body. Accurate detection of the phases of the gait in real-time is crucial to control lower-limb assistive devices like…

Signal Processing · Electrical Eng. & Systems 2024-03-12 Farhad Nazari , Navid Mohajer , Darius Nahavandi , Abbas Khosravi

Real-world digital Parkinson's disease assessment faces challenges such as heterogeneous modalities, cross-device bias, and incomplete labeling. Existing methods often focus on average predictive performance, lacking the reliability…

Machine Learning · Computer Science 2026-05-12 Wenbin Wei , Ruixiang Gao , Suyuan Yao , Xuanzhen Zhao , Cheng Huang , Hen-Wei Huang

Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

Applications · Statistics 2018-10-04 R Prashanth , Sumantra Dutta Roy

This study investigates the application of general human motion encoders trained on large-scale human motion datasets for analyzing gait patterns in PD patients. Although these models have learned a wealth of human biomechanical knowledge,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Vida Adeli , Soroush Mehraban , Irene Ballester , Yasamin Zarghami , Andrea Sabo , Andrea Iaboni , Babak Taati

Background: Parkinson's disease remains a major neurodegenerative disorder with high misdiagnosis rates, primarily due to reliance on clinical rating scales. Recent studies have demonstrated a strong association between gut microbiota and…

Artificial Intelligence · Computer Science 2025-09-10 Bo Yu , Zhixiu Hua , Bo Zhao

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuron loss and the accumulation of abnormal synuclein. PD presents both motor and non-motor symptoms that progressively impair…

Machine Learning · Computer Science 2025-04-07 Masahiro Matsumoto , Abu Saleh Musa Miah , Nobuyoshi Asai , Jungpil Shin

In this study we focus on the diagnosis of Parkinson's Disease (PD) based on electroencephalogram (EEG) signals. We propose a new approach inspired by the functioning of the brain that uses the dynamics, frequency and temporal content of…

Systems and Control · Electrical Eng. & Systems 2023-03-31 Houssem Meghnoudj , Bogdan Robu , Mazen Alamir

Gait recognition is a term commonly referred to as an identification problem within the Computer Science field. There are a variety of methods and models capable of identifying an individual based on their pattern of ambulatory locomotion.…

Machine Learning · Computer Science 2021-01-01 Ryan C. Saxe , Samantha Kappagoda , David K. A. Mordecai

Current humanoid push-recovery strategies often use whole-body motion, yet they tend to overlook posture regulation. For instance, in manipulation tasks, the upper body may need to stay upright and have minimal recovery displacement. This…

Robotics · Computer Science 2025-05-29 Junheng Li , Zhanhao Le , Junchao Ma , Quan Nguyen

Locked-in Syndrome patients are often misdiagnosed and face pessimistic prognosis because of similarities with disorders of consciousness, a lack of objective biomarkers and a difficult-to-recognize pathogenesis. Biomarkers show promise in…

Neurons and Cognition · Quantitative Biology 2020-06-23 Daniël van den Corput

The Internet of Medical Things (IoMT) paradigm is becoming mainstream in multiple clinical trials and healthcare procedures. Cardiovascular diseases monitoring, usually involving electrocardiogram (ECG) traces analysis, is one of the most…

Machine Learning · Computer Science 2021-07-26 Matteo Antonio Scrugli , Daniela Loi , Luigi Raffo , Paolo Meloni