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This paper presents the implementation of a quantum sequence alignment (QSA) algorithm on biological data in environments simulating noisy intermediate-scale quantum (NISQ) computers. The approach to quantum bioinformatics adapts the…

Quantum Physics · Physics 2025-07-02 Floyd M. Creevey , Mingrui Jing , Lloyd C. L. Hollenberg

Noisy Intermediate-Scale Quantum (NISQ) devices fail to produce outputs with sufficient fidelity for deep circuits with many gates today. Such devices suffer from read-out, multi-qubit gate and crosstalk noise combined with short…

Quantum Physics · Physics 2021-07-15 Ellis Wilson , Frank Mueller , Lindsay Bassman , Constin Iancu

The Variational Quantum Eigensolver (VQE) is a promising quantum algorithm for applications in chemistry within the Noisy Intermediate-Scale Quantum (NISQ) era. The ability for a quantum computer to simulate electronic structures with high…

With the surge of quantum computing platforms that continue to push the boundaries of capabilities of noisy intermediate-scale quantum computers, there is a growing interest in finding relevant applications and quantifying the corresponding…

Near-term quantum computers have been built as intermediate-scale quantum devices and are fragile against quantum noise effects, namely, NISQ devices. Traditional quantum-error-correcting codes are not implemented on such devices and to…

Quantum Physics · Physics 2024-03-18 Yusuke Hama , Hirofumi Nishi

Quantum Error Mitigation (QEM) enables the extraction of high-quality results from the presently-available noisy quantum computers. In this approach, the effect of the noise on observables of interest can be mitigated using multiple…

Quantum Physics · Physics 2023-11-23 Ivan Henao , Jader P. Santos , Raam Uzdin

Quantum error mitigation (QEM) provides a practical route for estimating reliable observables on noisy intermediate-scale quantum (NISQ) devices. Traditional QEM strategies, including zero-noise extrapolation (ZNE) and Clifford data…

Quantum Physics · Physics 2026-04-21 Huaxin Wang , Xinge Wu , Jiajun Liu , Ruiqing He , Jiandong Shang , Hengliang Guo , Qiang Chen

Quantum phase estimation (QPE) is a key quantum algorithm, which has been widely studied as a method to perform chemistry and solid-state calculations on future fault-tolerant quantum computers. Recently, several authors have proposed…

Quantum Physics · Physics 2024-02-05 Nick S. Blunt , Laura Caune , Róbert Izsák , Earl T. Campbell , Nicole Holzmann

Variational Quantum Algorithms (VQAs) combine quantum circuits with classical optimization to tackle problems that may benefit from the capabilities of near-term quantum hardware. In knowledge graph embedding, recent proposals based on this…

Quantum computational experiments exploiting Noisy Intermediate-Scale Quantum (NISQ) devices to demonstrate violation of a Bell inequality are proposed. They consist of running specified quantum algorithms on few-qubit computers. If such a…

Quantum Physics · Physics 2020-09-02 H. W. L. Naus , H. Polinder

Higher-dimensional quantum systems (qudits) offer advantages in information encoding, error resilience, and compact gate implementations, and naturally arise in platforms such as superconducting and solid-state systems. However, realistic…

Quantum Physics · Physics 2025-06-17 Yule Mayevsky , Akram Youssry , Ritik Sareen , Gerardo A. Paz-Silva , Alberto Peruzzo

Mapping logical quantum circuits to Noisy Intermediate-Scale Quantum (NISQ) devices is a challenging problem which has attracted rapidly increasing interests from both quantum and classical computing communities. This paper proposes an…

Quantum Physics · Physics 2021-09-23 Sanjiang Li , Xiangzhen Zhou , Yuan Feng

The steady progress of quantum hardware is motivating the search for novel quantum algorithm optimization strategies for near-term, real-world applications. In this study, we propose a novel feature map optimization strategy for Quantum…

Quantum Physics · Physics 2025-03-31 Roberto Moretti , Andrea Giachero , Voica Radescu , Michele Grossi

Noisy Intermediate-Scale Quantum (NISQ) machines are not fault-tolerant, operate few qubits (currently, less than hundred), but are capable of executing interesting computations. Above the quantum supremacy threshold (approx. 60 qubits),…

Quantum Physics · Physics 2019-01-31 Alexandru Paler

As a crossover frontier of physics and mechanics, quantum computing is showing its great potential in computational mechanics. However, quantum hardware noise remains a critical barrier to achieving accurate simulation results due to the…

Computational Engineering, Finance, and Science · Computer Science 2024-11-25 Zengtao Kuang , Yongchun Xu , Qun Huang , Jie Yang , Chafik El Kihal , Heng Hu

Quantum algorithm design usually assumes access to a perfect quantum computer with ideal properties like full connectivity, noise-freedom and arbitrarily long coherence time. In Noisy Intermediate-Scale Quantum (NISQ) devices, however, the…

Quantum Physics · Physics 2020-09-11 Xiangzhen Zhou , Sanjiang Li , Yuan Feng

One strategy to fit larger problems on NISQ devices is to exploit a tradeoff between circuit width and circuit depth. Unfortunately, this tradeoff still limits the size of tractable problems since the increased depth is often not realizable…

Quantum Physics · Physics 2021-09-08 Justin Yirka , Yigit Subasi

A variety of photon-mediated operations are critical to the realization of scalable quantum information processing platforms and their accurate characterization is essential for the identification of optimal regimes and their experimental…

Commercially available Noisy Intermediate-Scale Quantum (NISQ) devices now make small hybrid quantum-classical experiments practical, but many tools hide configuration or demand ad-hoc scripting. We introduce the Quantum Experiment…

Quantum Physics · Physics 2025-11-07 Vincent Gierisch , Wolfgang Mauerer

Quantum phase estimation~(QPE) is central to numerous quantum algorithms, yet its standard implementation demands an $\calO(m^{2})$-gate quantum Fourier transform~(QFT) on $m$ control qubits-a prohibitive overhead on near-term noisy…

Quantum Physics · Physics 2026-04-08 Akoramurthy B , Surendiran. B
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