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Lymphocyte populations, stimulated in vitro or in vivo, grow as cells divide. Stochastic models are appropriate because some cells undergo multiple rounds of division, some die, and others of the same type in the same conditions do not…

Cell Behavior · Quantitative Biology 2021-12-02 Giulia Belluccini , Martín López-García , Grant Lythe , Carmen Molina-París

The purpose of this paper is to analyze the mechanism for the interplay of deterministic and stochastic models for contagious diseases. Deterministic models for contagious diseases are prone to predict global stability. Small natural birth…

Populations and Evolution · Quantitative Biology 2022-06-17 Torsten Lindström

A wide range of stochastic processes that model the growth and decline of populations exhibit a curious dichotomy: with certainty either the population goes extinct or its size tends to infinity. There is a elegant and classical theorem…

Populations and Evolution · Quantitative Biology 2014-09-17 Mike Steel

The human adaptive immune response is known to weaken in advanced age, resulting in increased severity of pathogen-born illness, poor vaccine efficacy, and a higher prevalence of cancer in the elderly. Age-related erosion of the T-cell…

Populations and Evolution · Quantitative Biology 2019-01-03 Stephanie M. Lewkiewicz , Yao-Li Chuang , Tom Chou

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

Populations and Evolution · Quantitative Biology 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

We consider a stochastic model for an evolving population. We show that in the presence of genotype extinctions the population dies out for a low mutation probability but may survive for a high mutation probability. This turns upside down…

Populations and Evolution · Quantitative Biology 2014-10-24 Rinaldo B. Schinazi

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

Fluid Dynamics · Physics 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

In this work we address the analysis of discrete-time models of structured metapopulations subject to environmental stochasticity. Previous works on these models made use of the fact that migrations between the patches can be considered…

Populations and Evolution · Quantitative Biology 2024-02-07 Luis Sanz , Rafael Bravo de la Parra

We study the multi-species replicator model with linear fitness and random fitness matrices of various classes. By means of numerical resolution of the replicator equations, we determine the survival probability of a species in terms of its…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Sebastian Bouzat , Damian Zanette

Income inequality and redistribution policies are modeled with a minimal, endogenous model of a simple foraging economy. Significant income inequalities emerge from the model for populations of equally capable individuals presented with…

Physics and Society · Physics 2024-11-21 John C. Stevenson

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial persistence. To understand the strategy to control such…

Populations and Evolution · Quantitative Biology 2019-12-02 So Nakashima , Yuki Sughiyama , Tetsuya J. Kobayashi

The progression of a cell population where each individual is characterized by the value of an internal variable varying with time (e.g. size, weight, and protein concentration) is typically modeled by a Population Balance Equation, a first…

Cell Behavior · Quantitative Biology 2016-04-20 Qasim Ali , Ali Elkamel , Frédéric Gruy , Claude Lambert , Eric Touboul

In a previous paper, we have shown that a recurrent neural network (RNN) can be used to detect cellular network radio signal degradations accurately. We unexpectedly found, though, that accuracy gains diminished as we added layers to the…

Machine Learning · Computer Science 2024-04-18 David Mulvey , Chuan Heng Foh , Muhammad Ali Imran , Rahim Tafazolli

Epidemic outbreaks of new pathogens, or known pathogens in new populations, cause a great deal of fear because they are hard to predict. For theoretical models of disease spreading, on the other hand, quantities characterizing the outbreak…

Populations and Evolution · Quantitative Biology 2015-05-20 Petter Holme , Taro Takaguchi

In this manuscript, we continue with the systematic study of the speed of extinction of continuous state branching processes in L\'evy environments under more general branching mechanisms. Here, we deal with the weakly subcritical regime…

Probability · Mathematics 2023-02-20 Natalia Cardona-Tobón , Juan Carlos Pardo

We study the ABC model (A + B --> 2B, B + C --> 2C, C + A --> 2A), and its counterpart: the three--component neutral drift model (A + B --> 2A or 2B, B + C --> 2B or 2C, C + A --> 2C or 2A.) In the former case, the mean field approximation…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Margarita Ifti , Birger Bergersen

The global existence and boundedness of solutions to quasi-linear reaction-diffusion systems are investigated. The system arises from compartmental models describing the spread of infectious diseases proposed in [Viguerie et al, Appl. Math.…

Analysis of PDEs · Mathematics 2024-03-26 Juan Yang , Jeff Morgan , Bao Quoc Tang

We consider a population with non-overlapping generations, whose size goes to infinity. It is described by a discrete genealogy which may be time non-homogeneous and we pay special attention to branching trees in varying environments. A…

Probability · Mathematics 2013-05-22 Vincent Bansaye , Chunmao Huang

We consider a birth and death process in which death is due to both `natural death' and to competition between individuals, modelled as a quadratic function of population size. The resulting `logistic branching process' has been proposed as…

Probability · Mathematics 2013-10-23 Alison Etheridge , Shidong Wang , Feng Yu