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Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Optical coherence tomography (OCT) is a non-invasive imaging technology which can provide micrometer-resolution cross-sectional images of the inner structures of the eye. It is widely used for the diagnosis of ophthalmic diseases with…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Donghuan Lu , Morgan Heisler , Da Ma , Setareh Dabiri , Sieun Lee , Gavin Weiguang Ding , Marinko V. Sarunic , Mirza Faisal Beg

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

In this paper we propose a novel deep learning-based algorithm for biomedical image segmentation which uses a sequential attention mechanism able to shift the focus of attention across the image in a selective way, allowing subareas which…

Computer Vision and Pattern Recognition · Computer Science 2019-09-30 Shohei Hayashi , Bisser Raytchev , Toru Tamaki , Kazufumi Kaneda

Self-supervised Object Segmentation (SOS) aims to segment objects without any annotations. Under conditions of multi-camera inputs, the structural, textural and geometrical consistency among each view can be leveraged to achieve…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Xiaoyun Zheng , Liwei Liao , Jianbo Jiao , Feng Gao , Ronggang Wang

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

Purpose. This study was conducted to determine the thickness map of eleven retinal layers in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate their association with sex and age. Methods. Mean regional…

Computer Vision and Pattern Recognition · Computer Science 2013-12-12 Raheleh Kafieh , Hossein Rabbani , Fedra Hajizadeh , Michael D. Abramoff , Milan Sonka

The Segment Anything Model (SAM) has gained significant attention in the field of image segmentation due to its impressive capabilities and prompt-based interface. While SAM has already been extensively evaluated in various domains, its…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Botond Fazekas , José Morano , Dmitrii Lachinov , Guilherme Aresta , Hrvoje Bogunović

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Stefanos Apostolopoulos , Sandro De Zanet , Carlos Ciller , Sebastian Wolf , Raphael Sznitman

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

Focusing on the complicated pathological features, such as blurred boundaries, severe scale differences between symptoms, background noise interference, etc., in the task of retinal edema lesions joint segmentation from OCT images and…

Image and Video Processing · Electrical Eng. & Systems 2024-01-03 Meng Wang , Kai Yu , Chun-Mei Feng , Ke Zou , Yanyu Xu , Qingquan Meng , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Yufei Wang , Yiqing Shen , Meng Yuan , Jing Xu , Bin Yang , Chi Liu , Wenjia Cai , Weijing Cheng , Wei Wang

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that is becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Etienne Chollet , Yael Balbastre , Caroline Magnain , Bruce Fischl , Hui Wang

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

To study whether it is possible to differentiate intermediate age-related macular degeneration (AMD) from healthy controls using partial optical coherence tomography (OCT) data, that is, restricting the input B-scans to certain pre-defined…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Danilo A. Jesus , Eric F. Thee , Tim Doekemeijer , Daniel Luttikhuizen , Caroline Klaver , Stefan Klein , Theo van Walsum , Hans Vingerling , Luisa Sanchez

Purpose: The purpose of this study was to introduce SLOctolyzer: an open-source analysis toolkit for en face retinal vessels in infrared reflectance scanning laser ophthalmoscopy (SLO) images. Methods: SLOctolyzer includes two main modules:…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Jamie Burke , Samuel Gibbon , Justin Engelmann , Adam Threlfall , Ylenia Giarratano , Charlene Hamid , Stuart King , Ian J. C. MacCormick , Tom MacGillivray

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality for the visualisation of microvasculature in vivo that has encountered broad adoption in retinal research. OCTA potential in the assessment of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ylenia Giarratano , Eleonora Bianchi , Calum Gray , Andrew Morris , Tom MacGillivray , Baljean Dhillon , Miguel O. Bernabeu

Optical Coherence Tomography Angiography (OCT-A) is a non-invasive imaging technique, and has been increasingly used to image the retinal vasculature at capillary level resolution. However, automated segmentation of retinal vessels in OCT-A…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Yuhui Ma , Huaying Hao , Huazhu Fu , Jiong Zhang , Jianlong Yang , Jiang Liu , Yalin Zheng , Yitian Zhao