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Stress is widely recognized as a major contributor to a variety of health issues. Stress prediction using biosignal data recorded by wearables is a key area of study in mobile sensing research because real-time stress prediction can enable…

Machine Learning · Computer Science 2023-08-14 Tanvir Islam , Peter Washington

Continuing advances in neural interfaces have enabled simultaneous monitoring of spiking activity from hundreds to thousands of neurons. To interpret these large-scale data, several methods have been proposed to infer latent dynamic…

Machine Learning · Computer Science 2019-08-23 Mohammad Reza Keshtkaran , Chethan Pandarinath

There is an increasing recognition of the role of brain networks as neuroimaging biomarkers in mental health and psychiatric studies. Our focus is posttraumatic stress disorder (PTSD), where the brain network interacts with environmental…

Methodology · Statistics 2019-10-10 Xin Ma , Suprateek Kundu , Jennifer Stevens

Chronic stress can significantly affect physical and mental health. The advent of wearable technology allows for the tracking of physiological signals, potentially leading to innovative stress prediction and intervention methods. However,…

Machine Learning · Computer Science 2023-08-08 Tanvir Islam , Peter Washington

With the growing popularity of wearable devices, the ability to utilize physiological data collected from these devices to predict the wearer's mental state such as mood and stress suggests great clinical applications, yet such a task is…

Machine Learning · Computer Science 2019-06-28 Abhinav Shaw , Natcha Simsiri , Iman Deznaby , Madalina Fiterau , Tauhidur Rahaman

To improve the statistical power for imaging biomarker detection, we propose a latent variable-based statistical network analysis (LatentSNA) that combines brain functional connectivity with internalizing psychopathology, implementing…

Methodology · Statistics 2023-09-21 Selena Wang , Yunhe Liu , Wanwan Xu , Xinyuan Tian , Yize Zhao

In this paper we present a new approach to solve semi-supervised classification tasks for biomedical applications, involving a supervised autoencoder network. We create a network architecture that encodes labels into the latent space of an…

Machine Learning · Computer Science 2022-08-24 Cyprien Gille , Frederic Guyard , Michel Barlaud

Sparse autoencoders (SAEs) model the activations of a neural network as linear combinations of sparsely occurring directions of variation (latents). The ability of SAEs to reconstruct activations follows scaling laws w.r.t. the number of…

Machine Learning · Computer Science 2025-09-05 Eric J. Michaud , Liv Gorton , Tom McGrath

Functional development of affective and reward circuits, cognition and response inhibition later in life exhibits vulnerability periods during gestation and early childhood. Extensive evidence supports the model that exposure to stressors…

Quantitative Methods · Quantitative Biology 2021-02-26 Marta C. Antonelli , Martin G. Frasch , Mercedes Rumi , Ritika Sharma , Peter Zimmermann , Maria Sol Molinet , Silvia M. Lobmaier

Recent work shows that Sparse Autoencoders (SAE) applied to large language model (LLM) layers have neurons corresponding to interpretable concepts. These SAE neurons can be modified to align generated outputs, but only towards…

Computation and Language · Computer Science 2025-07-01 Ananya Joshi , Celia Cintas , Skyler Speakman

Transformer models have become state-of-the-art in decoding stimuli and behavior from neural activity, significantly advancing neuroscience research. Yet greater transparency in their decision-making processes would substantially enhance…

Quantitative Methods · Quantitative Biology 2025-06-18 Laurence Freeman , Philip Shamash , Vinam Arora , Caswell Barry , Tiago Branco , Eva Dyer

Sparse autoencoders (SAEs) have lately been used to uncover interpretable latent features in large language models. By projecting dense embeddings into a much higher-dimensional and sparse space, learned features become disentangled and…

Machine Learning · Computer Science 2025-07-30 Viktoria Schuster

A recent line of work has shown promise in using sparse autoencoders (SAEs) to uncover interpretable features in neural network representations. However, the simple linear-nonlinear encoding mechanism in SAEs limits their ability to perform…

Machine Learning · Computer Science 2025-01-31 Charles O'Neill , Alim Gumran , David Klindt

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Sparse Autoencoders (SAEs) are a promising approach for extracting neural network representations by learning a sparse and overcomplete decomposition of the network's internal activations. However, SAEs are traditionally trained considering…

Machine Learning · Computer Science 2025-04-02 Jeffrey Olmo , Jared Wilson , Max Forsey , Bryce Hepner , Thomas Vin Howe , David Wingate

Physiological measurements involves observing variables that attribute to the normative functioning of human systems and subsystems directly or indirectly. The measurements can be used to detect affective states of a person with aims such…

Machine Learning · Computer Science 2022-10-31 Nibraas Khan , Nilanjan Sarkar

Sparse autoencoders (SAEs) are a mechanistic interpretability technique that have been used to provide insight into learned concepts within large protein language models. Here, we employ TopK and Ordered SAEs to investigate autoregressive…

Variational autoencoder (VAE) neural networks can be trained to generate power system states that capture both marginal distribution and multivariate dependencies of historical data. The coordinates of the latent space codes of VAEs have…

Systems and Control · Electrical Eng. & Systems 2023-03-22 Chenguang Wang , Ensieh Sharifnia , Simon H. Tindemans , Peter Palensky

In this paper, we investigate the usage of autoencoders in modeling textual data. Traditional autoencoders suffer from at least two aspects: scalability with the high dimensionality of vocabulary size and dealing with task-irrelevant words.…

Machine Learning · Computer Science 2015-12-15 Shuangfei Zhai , Zhongfei Zhang

Decomposing model activations into interpretable components is a key open problem in mechanistic interpretability. Sparse autoencoders (SAEs) are a popular method for decomposing the internal activations of trained transformers into sparse,…

Machine Learning · Computer Science 2024-06-26 Connor Kissane , Robert Krzyzanowski , Joseph Isaac Bloom , Arthur Conmy , Neel Nanda
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