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Related papers: QuASeR -- Quantum Accelerated De Novo DNA Sequence…

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QASMTrans is a lightweight, high-performance, C++-based quantum compiler that bridges abstract quantum algorithms to device-level control and is designed for just-in-time (JIT) deployment on QPU testbeds with tightly integrated FPGAs or…

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh

De novo whole genome assembly reconstructs genomic sequence from short, overlapping, and potentially erroneous DNA segments and is one of the most important computations in modern genomics. This work presents HipMER, a high-quality…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-01 Evangelos Georganas , Steven Hofmeyr , Rob Egan , Aydin Buluc , Leonid Oliker , Daniel Rokhsar , Katherine Yelick

The state vector-based simulation offers a convenient approach to developing and validating quantum algorithms with noise-free results. However, limited by the absence of cache-aware implementations and unpolished circuit optimizations, the…

Quantum Physics · Physics 2024-06-21 Chuan-Chi Wang , Yu-Cheng Lin , Yan-Jie Wang , Chia-Heng Tu , Shih-Hao Hung

Progress in the realisation of reliable large-scale quantum computers has motivated research into the design of quantum machine learning models. We present Quixer: a novel quantum transformer model which utilises the Linear Combination of…

Quantum Physics · Physics 2024-06-07 Nikhil Khatri , Gabriel Matos , Luuk Coopmans , Stephen Clark

Variational quantum algorithms hold the promise to address meaningful quantum problems already on noisy intermediate-scale quantum hardware. In spite of the promise, they face the challenge of designing quantum circuits that both solve the…

Quantum Physics · Physics 2025-10-01 Akash Kundu , Stefano Mangini

Genetic analysis methods are foundational to advancing personalized and preventative medicine, accelerating disease diagnostics, and monitoring the health of organisms and ecosystems. Current nucleic acid technologies such as polymerase…

We consider the correction of errors from nucleotide sequences produced by next-generation targeted amplicon sequencing. The next-generation sequencing (NGS) platforms can provide a great deal of sequencing data thanks to their high…

Genomics · Quantitative Biology 2017-07-05 Byunghan Lee , Taesup Moon , Sungroh Yoon , Tsachy Weissman

We present QFAST, a quantum synthesis tool designed to produce short circuits and to scale well in practice. Our contributions are: 1) a novel representation of circuits able to encode placement and topology; 2) a hierarchical approach with…

Quantum Physics · Physics 2020-03-27 Ed Younis , Koushik Sen , Katherine Yelick , Costin Iancu

Genetic algorithms, which mimic evolutionary processes to solve optimization problems, can be enhanced by using powerful semi-local search algorithms as mutation operators. Here, we introduce reverse quantum annealing, a class of quantum…

In the Noisy Intermediate-Scale Quantum (NISQ) era, limited qubit counts and high gate error rates directly constrain circuit fidelity, making the minimization of CNOT gate counts crucial. While conventional compilers prioritize heuristic…

Quantum Physics · Physics 2026-05-13 Kazuma Watanabe , Hideaki Kawaguchi , Shin Nishio , Takahiko satoh

Peptide de novo sequencing is a method used to reconstruct amino acid sequences from tandem mass spectrometry data without relying on existing protein sequence databases. Traditional deep learning approaches, such as Casanovo, mainly…

Machine Learning · Computer Science 2025-07-16 Chi-en Amy Tai , Alexander Wong

As quantum computing progresses, traditional cryptographic systems face the threat of obsolescence due to the capabilities of quantum algorithms. This paper introduces the Quantum-Ready Architecture for Security and Risk Management…

Cryptography and Security · Computer Science 2025-05-26 Abraham Itzhak Weinberg

Quantum computers hold great promise for accelerating computationally challenging algorithms on noisy intermediate-scale quantum (NISQ) devices in the upcoming years. Much attention of the current research is directed to algorithmic…

Reliably transmitting quantum information via a noisy quantum channel is a central challenge in quantum information science. While constructing a decoder is crucial to this goal, little was known about quantum circuit implementations of…

Quantum Physics · Physics 2026-03-18 Takeru Utsumi , Yoshifumi Nakata

The advent of next-generation sequencing (NGS) has revolutionized genomic research by enabling cost-effective, high-throughput sequencing of a diverse range of organisms. This breakthrough has unleashed a "Cambrian explosion" in genomic…

Quantum receivers aim to effectively navigate the vast quantum-state space to endow quantum information processing capabilities unmatched by classical receivers. To date, only a handful of quantum receivers have been constructed to tackle…

Quantum computers hold immense potential in the field of chemistry, ushering new frontiers to solve complex many body problems that are beyond the reach of classical computers. However, noise in the current quantum hardware limits their…

Quantum Physics · Physics 2024-03-20 Chayan Patra , Sonaldeep Halder , Rahul Maitra

The automated design of parameterized quantum circuits for variational algorithms in the NISQ era faces a fundamental limitation, as conventional differentiable architecture search relies on classical models that fail to adequately…

Quantum Physics · Physics 2025-12-03 Yuxiang Liu , Sixuan Li , Fanxu Meng , Zaichen Zhang , Xutao Yu

This paper proposes a quantum computing-based algorithm to solve the single image super-resolution (SISR) problem. One of the well-known classical approaches for SISR relies on the well-established patch-wise sparse modeling of the problem.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Han Yao Choong , Suryansh Kumar , Luc Van Gool
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