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Multi-objective Bayesian optimization (MOBO) provides a principled framework for navigating trade-offs in molecular design. However, its empirical advantages over scalarized alternatives remain underexplored. We benchmark a simple…

Machine Learning · Computer Science 2025-12-25 Anabel Yong , Austin Tripp , Layla Hosseini-Gerami , Brooks Paige

Multi-objective alignment from human feedback (MOAHF) in large language models (LLMs) is a challenging problem as human preferences are complex, multifaceted, and often conflicting. Recent works on MOAHF considered a-priori multi-objective…

Machine Learning · Computer Science 2024-12-10 Subhojyoti Mukherjee , Anusha Lalitha , Sailik Sengupta , Aniket Deshmukh , Branislav Kveton

Optimisation problems often have multiple conflicting objectives that can be computationally and/or financially expensive. Mono-surrogate Bayesian optimisation (BO) is a popular model-based approach for optimising such black-box functions.…

Machine Learning · Computer Science 2022-08-11 George De Ath , Tinkle Chugh , Alma A. M. Rahat

Dynamic Multi-objective Optimization Problems (DMOPs) refer to optimization problems that objective functions will change with time. Solving DMOPs implies that the Pareto Optimal Set (POS) at different moments can be accurately found, and…

Artificial Intelligence · Computer Science 2019-10-22 Min Jiang , Weizhen Hu , Liming Qiu , Minghui Shi , Kay Chen Tan

Purpose: Current inverse planning methods for IMRT are limited because they are not designed to explore the trade-offs between the competing objectives between the tumor and normal tissues. Our goal was to develop an efficient…

Medical Physics · Physics 2015-06-04 Clay Holdsworth , Minsun Kim , Jay Liao , Mark H Phillips

The Multi-Objective Real-Valued Gene-pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA) has been proven effective and efficient in solving real-world problems. A prime example is optimizing treatment plans for prostate cancer…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Leah R. M. Dickhoff , Ellen M. Kerkhof , Heloisa H. Deuzeman , Carien L. Creutzberg , Tanja Alderliesten , Peter A. N. Bosman

In Symbolic Regression (SR), achieving a proper balance between accuracy and interpretability remains a key challenge. The Genetic Programming variant of the Gene-pool Optimal Mixing Evolutionary Algorithm (GP-GOMEA) is of particular…

Neural and Evolutionary Computing · Computer Science 2025-07-08 Joe Harrison , Tanja Alderliesten. Peter A. N. Bosman

Multi-objective Bayesian optimization (MOBO) provides a principled framework for optimizing expensive black-box functions with multiple objectives. However, existing MOBO methods often struggle with coverage, scalability with respect to the…

Machine Learning · Computer Science 2026-04-20 Yaohong Yang , Sammie Katt , Samuel Kaski

Multi-Objective Evolutionary Algorithms (MOEAs) have been proved efficient to deal with Multi-objective Optimization Problems (MOPs). Until now tens of MOEAs have been proposed. The unified mode would provide a more systematic approach to…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Bojin Zheng , Yuanxiang Li

Single-objective black box optimization (also known as zeroth-order optimization) is the process of minimizing a scalar objective $f(x)$, given evaluations at adaptively chosen inputs $x$. In this paper, we consider multi-objective…

Machine Learning · Computer Science 2020-06-11 Daniel Golovin , Qiuyi Zhang

In this letter, we propose HV-Net, a new method for hypervolume approximation in evolutionary multi-objective optimization. The basic idea of HV-Net is to use DeepSets, a deep neural network with permutation invariant property, to…

Neural and Evolutionary Computing · Computer Science 2022-03-07 Ke Shang , Weiyu Chen , Weiduo Liao , Hisao Ishibuchi

We propose a multi-objective optimization algorithm aimed at achieving good anytime performance over a wide range of problems. Performance is assessed in terms of the hypervolume metric. The algorithm called HMO-CMA-ES represents a hybrid…

Neural and Evolutionary Computing · Computer Science 2016-05-10 Ilya Loshchilov , Tobias Glasmachers

In this article, we present a framework for taking into account user preferences in multi-objective Bayesian optimization in the case where the objectives are expensive-to-evaluate black-box functions. A novel expected improvement criterion…

Optimization and Control · Mathematics 2018-09-17 Paul Feliot , Julien Bect , Emmanuel Vazquez

Multi-objective evolutionary algorithms (MOEAs) have become essential tools for solving multi-objective optimization problems (MOPs), making their running time analysis crucial for assessing algorithmic efficiency and guiding practical…

Neural and Evolutionary Computing · Computer Science 2025-07-04 Han Huang , Tianyu Wang , Chaoda Peng , Tongli He , Zhifeng Hao

Scalability of evolutionary algorithms refers to assessing how their performance changes as problem size increases. In the area of multi-objective optimisation, research on the scalability of multi-objective evolutionary algorithms (MOEAs)…

Neural and Evolutionary Computing · Computer Science 2026-04-21 Menghao Tang , Zimin Liang , Miqing Li

Finding a large set of optima in a multimodal optimization landscape is a challenging task. Classical population-based evolutionary algorithms typically converge only to a single solution. While this can be counteracted by applying niching…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Benjamin Doerr , Martin S. Krejca

When working with decomposition-based algorithms, an appropriate set of weights might improve quality of the final solution. A set of uniformly distributed weights usually leads to well-distributed solutions on a Pareto front. However,…

Neural and Evolutionary Computing · Computer Science 2020-03-26 Lucas R. C. de Farias , Pedro H. M. Braga , Hansenclever F. Bassani , Aluizio F. R. Araújo

Decomposition has been the mainstream approach in classic mathematical programming for multi-objective optimization and multi-criterion decision-making. However, it was not properly studied in the context of evolutionary multi-objective…

Neural and Evolutionary Computing · Computer Science 2024-10-23 Ke Li

In a Gray-Box Optimization (GBO) setting that allows for partial evaluations, the fitness of an individual can be updated efficiently after a subset of its variables has been modified. This enables more efficient evolutionary optimization…

Neural and Evolutionary Computing · Computer Science 2022-03-17 Anton Bouter , Peter A. N. Bosman

The main goal of diversity optimization is to find a diverse set of solutions which satisfy some lower bound on their fitness. Evolutionary algorithms (EAs) are often used for such tasks, since they are naturally designed to optimize…

Neural and Evolutionary Computing · Computer Science 2024-07-15 Denis Antipov , Aneta Neumann , Frank Neumann