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Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Often in medical imaging, it is prohibitively challenging to produce enough boundary annotations to train deep neural networks for accurate tumor segmentation. We propose the use of weak labels about whether an image presents tumor or…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Eugene Vorontsov , Pavlo Molchanov , Christopher Beckham , Jan Kautz , Samuel Kadoury

Instance segmentation in 3D images is a fundamental task in biomedical image analysis. While deep learning models often work well for 2D instance segmentation, 3D instance segmentation still faces critical challenges, such as insufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Zhuo Zhao , Lin Yang , Hao Zheng , Ian H. Guldner , Siyuan Zhang , Danny Z. Chen

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Heather D. Couture , J. S. Marron , Charles M. Perou , Melissa A. Troester , Marc Niethammer

Polyp segmentation is a crucial step towards computer-aided diagnosis of colorectal cancer. However, most of the polyp segmentation methods require pixel-wise annotated datasets. Annotated datasets are tedious and time-consuming to produce,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Guangyu Ren , Michalis Lazarou , Jing Yuan , Tania Stathaki

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Background and objectives: Colorectal cancer histopathological grading depends on accurate segmentation of glandular structures. Current deep learning approaches rely on large scale pixel level annotations that are labor intensive and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Hikmat Khan , Wei Chen , Muhammad Khalid Khan Niazi

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

We present a novel approach to train pixel resolution segmentation models on whole slide images in a weakly supervised setup. The model is trained to classify patches extracted from slides. This leads the training to be made under noisy…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Nicolas Pinchaud

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Machine learning has been widely adopted for medical image analysis in recent years given its promising performance in image segmentation and classification tasks. As a data-driven science, the success of machine learning, in particular…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Chengliang Dai , Shuo Wang , Yuanhan Mo , Kaichen Zhou , Elsa Angelini , Yike Guo , Wenjia Bai

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

The segmentation of histopathological whole slide images into tumourous and non-tumourous types of tissue is a challenging task that requires the consideration of both local and global spatial contexts to classify tumourous regions…

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig