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Recently, molecule generation using deep learning has been actively investigated in drug discovery. In this field, Transformer and VAE are widely used as powerful models, but they are rarely used in combination due to structural and…

Biomolecules · Quantitative Biology 2024-04-08 Yasuhiro Yoshikai , Tadahaya Mizuno , Shumpei Nemoto , Hiroyuki Kusuhara

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Variational auto-encoders (VAEs) are an influential and generally-used class of likelihood-based generative models in unsupervised learning. The likelihood-based generative models have been reported to be highly robust to the…

Machine Learning · Computer Science 2020-10-06 Xuming Ran , Mingkun Xu , Qi Xu , Huihui Zhou , Quanying Liu

Deep neural network models trained on large labeled datasets are the state-of-the-art in a large variety of computer vision tasks. In many applications, however, labeled data is expensive to obtain or requires a time consuming manual…

Machine Learning · Computer Science 2017-12-01 Sergey Tulyakov , Andrew Fitzgibbon , Sebastian Nowozin

Deep generative models are reported to be useful in broad applications including image generation. Repeated inference between data space and latent space in these models can denoise cluttered images and improve the quality of inferred…

Machine Learning · Statistics 2017-12-13 Yoshihiro Nagano , Ryo Karakida , Masato Okada

Measurement of a physical quantity such as light intensity is an integral part of many reconstruction and decision scenarios but can be costly in terms of acquisition time, invasion of or damage to the environment and storage. Data…

Machine Learning · Computer Science 2025-02-26 Catherine F. Higham , Paul Henderson , Roderick Murray-Smith

Variational autoencoders (VAEs) rely on amortized variational inference to enable efficient posterior approximation, but this efficiency comes at the cost of a shared parametrization, giving rise to the amortization gap. We propose the…

Machine Learning · Computer Science 2026-04-21 Andrea Pollastro , Andrea Apicella , Francesco Isgrò , Roberto Prevete

This project report compares some known GAN and VAE models proposed prior to 2017. There has been significant progress after we finished this report. We upload this report as an introduction to generative models and provide some personal…

Machine Learning · Computer Science 2018-12-19 Lu Mi , Macheng Shen , Jingzhao Zhang

Clustering using deep neural network models have been extensively studied in recent years. Among the most popular frameworks are the VAE and GAN frameworks, which learns latent feature representations of data through encoder / decoder…

Machine Learning · Computer Science 2021-05-14 Adam Lindhe , Carl Ringqvist , Henrik Hult

Variational auto-encoders (VAEs) are a popular and powerful deep generative model. Previous works on VAEs have assumed a factorized likelihood model, whereby the output uncertainty of each pixel is assumed to be independent. This…

Machine Learning · Statistics 2026-05-14 Gara Dorta , Sara Vicente , Lourdes Agapito , Neill D. F. Campbell , Ivor Simpson

The variational autoencoder (VAE; Kingma, Welling (2014)) is a recently proposed generative model pairing a top-down generative network with a bottom-up recognition network which approximates posterior inference. It typically makes strong…

Machine Learning · Computer Science 2016-11-08 Yuri Burda , Roger Grosse , Ruslan Salakhutdinov

Clustering is among the most fundamental tasks in computer vision and machine learning. In this paper, we propose Variational Deep Embedding (VaDE), a novel unsupervised generative clustering approach within the framework of Variational…

Computer Vision and Pattern Recognition · Computer Science 2017-06-29 Zhuxi Jiang , Yin Zheng , Huachun Tan , Bangsheng Tang , Hanning Zhou

The Gaussianity assumption has been consistently criticized as a main limitation of the Variational Autoencoder (VAE) despite its efficiency in computational modeling. In this paper, we propose a new approach that expands the model capacity…

Machine Learning · Statistics 2023-10-30 Seunghwan An , Jong-June Jeon

Recently, the introduction of the generative adversarial network (GAN) and its variants has enabled the generation of realistic synthetic samples, which has been used for enlarging training sets. Previous work primarily focused on data…

Machine Learning · Computer Science 2018-08-27 Swee Kiat Lim , Yi Loo , Ngoc-Trung Tran , Ngai-Man Cheung , Gemma Roig , Yuval Elovici

Generative modeling and self-supervised learning have in recent years made great strides towards learning from data in a completely unsupervised way. There is still however an open area of investigation into guiding a neural network to…

Machine Learning · Computer Science 2023-05-17 Vaishnavi Patil , Matthew Evanusa , Joseph JaJa

Deep metric learning has been demonstrated to be highly effective in learning semantic representation and encoding information that can be used to measure data similarity, by relying on the embedding learned from metric learning. At the…

Machine Learning · Statistics 2023-02-09 Haque Ishfaq , Assaf Hoogi , Daniel Rubin

As one of the most popular generative models, Variational Autoencoder (VAE) approximates the posterior of latent variables based on amortized variational inference. However, when the decoder network is sufficiently expressive, VAE may lead…

Machine Learning · Computer Science 2021-10-26 Dazhong Shen , Chuan Qin , Chao Wang , Hengshu Zhu , Enhong Chen , Hui Xiong

While generative models have shown great success in generating high-dimensional samples conditional on low-dimensional descriptors (learning e.g. stroke thickness in MNIST, hair color in CelebA, or speaker identity in Wavenet), their…

Machine Learning · Computer Science 2019-10-31 Mohammad Lotfollahi , Mohsen Naghipourfar , Fabian J. Theis , F. Alexander Wolf

VAE, or variational auto-encoder, compresses data into latent attributes, and generates new data of different varieties. VAE based on KL divergence has been considered as an effective technique for data augmentation. In this paper, we…

Machine Learning · Computer Science 2022-08-17 Zichuan Chen , Peng Liu

We propose a composable framework for latent space image augmentation that allows for easy combination of multiple augmentations. Image augmentation has been shown to be an effective technique for improving the performance of a wide variety…

Machine Learning · Computer Science 2023-03-08 Omead Pooladzandi , Jeffrey Jiang , Sunay Bhat , Gregory Pottie