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Diffeomorphic image registration, offering smooth transformation and topology preservation, is required in many medical image analysis tasks.Traditional methods impose certain modeling constraints on the space of admissible transformations…

Computer Vision and Pattern Recognition · Computer Science 2022-11-03 Kun Han , Shanlin sun , Xiangyi Yan , Chenyu You , Hao Tang , Junayed Naushad , Haoyu Ma , Deying Kong , Xiaohui Xie

Standard registration algorithms need to be independently applied to each surface to register, following careful pre-processing and hand-tuning. Recently, learning-based approaches have emerged that reduce the registration of new scans to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Mehdi Bahri , Eimear O' Sullivan , Shunwang Gong , Feng Liu , Xiaoming Liu , Michael M. Bronstein , Stefanos Zafeiriou

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

The majority of current research in deep learning based image registration addresses inter-patient brain registration with moderate deformation magnitudes. The recent Learn2Reg medical registration benchmark has demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Mattias P. Heinrich , Lasse Hansen

We present a keypoint-based foundation model for general purpose brain MRI registration, based on the recently-proposed KeyMorph framework. Our model, called BrainMorph, serves as a tool that supports multi-modal, pairwise, and scalable…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Alan Q. Wang , Rachit Saluja , Heejong Kim , Xinzi He , Adrian Dalca , Mert R. Sabuncu

Registration is a fundamental task in medical image analysis which can be applied to several tasks including image segmentation, intra-operative tracking, multi-modal image alignment, and motion analysis. Popular registration tools such as…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Wentao Zhu , Andriy Myronenko , Ziyue Xu , Wenqi Li , Holger Roth , Yufang Huang , Fausto Milletari , Daguang Xu

Traditional deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Soft-tissue deformation remains a major limitation in image-guided neurosurgery, where intra-operative anatomy can deviate substantially from pre-operative imaging due to brain shift, compromising navigation accuracy and surgical safety.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Eashrat Jahan Muniya , Gernot Kronreif , Ander Biguri , Wolfgang Birkfellner , Sepideh Hatamikia

Convolutional neural network (CNN) slides a kernel over the whole image to produce an output map. This kernel scheme reduces the number of parameters with respect to a fully connected neural network (NN). While CNN has proven to be an…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Ihsan Ullah , Alfredo Petrosino

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Convolution as inner product has been the founding basis of convolutional neural networks (CNNs) and the key to end-to-end visual representation learning. Benefiting from deeper architectures, recent CNNs have demonstrated increasingly…

Machine Learning · Computer Science 2018-01-31 Weiyang Liu , Yan-Ming Zhang , Xingguo Li , Zhiding Yu , Bo Dai , Tuo Zhao , Le Song

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

In medical imaging, surface registration is extensively used for performing systematic comparisons between anatomical structures, with a prime example being the highly convoluted brain cortical surfaces. To obtain a meaningful registration,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Yuchen Guo , Qiguang Chen , Gary P. T. Choi , Lok Ming Lui

Image registration is a fundamental task in medical image analysis. Recently, deep learning based image registration methods have been extensively investigated due to their excellent performance despite the ultra-fast computational time.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Boah Kim , Dong Hwan Kim , Seong Ho Park , Jieun Kim , June-Goo Lee , Jong Chul Ye

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

Complicated image registration is a key issue in medical image analysis, and deep learning-based methods have achieved better results than traditional methods. The methods include ConvNet-based and Transformer-based methods. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Runshi Zhang , Hao Mo , Junchen Wang , Bimeng Jie , Yang He , Nenghao Jin , Liang Zhu

Current brain surface-based prediction models often overlook the variability of regional attributes at the cortical feature level. While graph neural networks (GNNs) excel at capturing regional differences, they encounter challenges when…

Neurons and Cognition · Quantitative Biology 2024-11-12 Zhuoshuo Li , Jiong Zhang , Youbing Zeng , Jiaying Lin , Dan Zhang , Jianjia Zhang , Duan Xu , Hosung Kim , Bingguang Liu , Mengting Liu

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez