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Species tree estimation from multi-locus datasets is statistically challenging for multiple reasons, including gene tree heterogeneity across the genome due to incomplete lineage sorting (ILS). Species tree estimation methods have been…

Populations and Evolution · Quantitative Biology 2020-01-23 John A. Rhodes , Michael G. Nute , Tandy Warnow

Inference of the evolutionary histories of species, commonly represented by a species tree, is complicated by the divergent evolutionary history of different parts of the genome. Different loci on the genome can have different histories…

Populations and Evolution · Quantitative Biology 2020-10-14 Andrew Richards , Laura Kubatko

ASTRAL is a method for reconstructing species trees after inferring a set of gene trees and is increasingly used in phylogenomic analyses. It is statistically consistent under the multi-species coalescent model, is scalable, and has shown…

Populations and Evolution · Quantitative Biology 2019-10-18 Siavash Mirarab

Species tree reconstruction is complicated by effects of Incomplete Lineage Sorting (ILS), commonly modeled by the multi-species coalescent model. While there has been substantial progress in developing methods that estimate a species tree…

Quantitative Methods · Quantitative Biology 2016-05-10 Erfan Sayyari , Siavash Mirarab

We consider species tree estimation under a standard stochastic model of gene tree evolution that incorporates incomplete lineage sorting (as modeled by a coalescent process) and gene duplication and loss (as modeled by a branching…

Probability · Mathematics 2020-07-15 Max Hill , Brandon Legried , Sebastien Roch

Recently, there has been interest in extending long-known results about the multispecies coalescent tree to other models of gene trees. Results about the gene duplication and loss (GDL) tree have mathematical proofs, including species tree…

Populations and Evolution · Quantitative Biology 2024-04-01 Brandon Legried

The multispecies coalescent model describes the generation of gene trees from a rooted metric species tree, and thus provides a framework for the inference of species trees from sampled gene trees. We prove that the STAR method of Liu et…

Populations and Evolution · Quantitative Biology 2012-04-20 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Incomplete lineage sorting (ILS) is a common source of gene tree incongruence in multilocus analyses. A large number of methods have been developed to infer species trees in the presence of ILS. Here we provide a mathematical analysis of…

Probability · Mathematics 2012-07-18 Sebastien Roch

Most current methods for inferring species-level phylogenies under the coalescent model assume that no gene flow occurs following speciation. While some studies have examined the impact of gene flow on estimation accuracy for certain…

Populations and Evolution · Quantitative Biology 2017-10-12 Colby Long , Laura Kubatko

Under the multispecies coalescent model of molecular evolution, gene trees have independent evolutionary histories within a shared species tree. In comparison, supermatrix concatenation methods assume that gene trees share a single common…

Populations and Evolution · Quantitative Biology 2016-06-13 Huw A. Ogilvie , Joseph Heled , Dong Xie , Alexei J. Drummond

The $\text{NJ}_{st}$ method was proposed by Liu and Yu to infer a species tree topology from unrooted topological gene trees. While its statistical consistency under the multispecies coalescent model was established only for a 4-taxon tree,…

Populations and Evolution · Quantitative Biology 2016-04-20 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

In phylogenomics, species-tree methods must contend with two major sources of noise; stochastic gene-tree variation under the multispecies coalescent model (MSC) and finite-sequence substitutional noise. Fast agglomerative methods such as…

Populations and Evolution · Quantitative Biology 2025-07-11 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

Populations and Evolution · Quantitative Biology 2015-12-15 Bruce Rannala , Ziheng Yang

As genomic scale datasets motivate research on species tree inference, simulators of the multispecies coalescent (MSC) process are essential for the testing and evaluation of new inference methods. However, the simulators themselves must be…

Populations and Evolution · Quantitative Biology 2019-08-06 Elizabeth S. Allman , Hector Baños , John A. Rhodes

Coalescent models of evolution account for incomplete lineage sorting by specifying a species tree parameter which determines a distribution on gene trees. It has been shown that the unrooted topology of the species tree parameter of the…

Populations and Evolution · Quantitative Biology 2017-01-25 Colby Long , Laura Kubatko

Diffusion language models (DLMs) have recently emerged as a compelling alternative to autoregressive generation, offering parallel generation and improved global coherence. During inference, DLMs generate text by iteratively denoising…

Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent…

Populations and Evolution · Quantitative Biology 2010-07-30 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Species tree reconstruction from genomic data is increasingly performed using methods that account for sources of gene tree discordance such as incomplete lineage sorting. One popular method for reconstructing species trees from unrooted…

Populations and Evolution · Quantitative Biology 2017-12-06 Shubhanshu Shekhar , Sebastien Roch , Siavash Mirarab

Bipartition cover probabilities quantify whether a collection of gene trees contains every bipartition of the underlying species tree, a condition that underlies finite-sample guarantees for summary methods such as ASTRAL. We study this…

Probability · Mathematics 2026-04-13 Zachary McNulty

Evolutionary events such as incomplete lineage sorting and lateral gene transfer constitute major problems for inferring species trees from gene trees, as they can sometimes lead to gene trees which conflict with the underlying species…

Populations and Evolution · Quantitative Biology 2013-04-23 Andreas Sand , Mike Steel
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