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Social distancing and isolation have been introduced widely to counter the COVID-19 pandemic. However, more moderate contact reduction policies become desirable owing to adverse social, psychological, and economic consequences of a complete…

The main goal of this paper is to model the epidemic and flattening the infection curve of the social networks. Flattening the infection curve implies slowing down the spread of the disease and reducing the infection rate via…

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

Populations and Evolution · Quantitative Biology 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara

Social distancing has been enacted in order to mitigate the spread of COVID-19. Like many authors, we adopt the classic epidemic SIR model, where the infection rate is the control variable. Its differential flatness property yields ele…

Systems and Control · Electrical Eng. & Systems 2022-10-05 Michel Fliess , Cédric Join , Alberto d'Onofrio

The death toll for Covid-19 may be reduced by dividing the population into two classes, the vulnerable and the fit, with different lockdown regimes. Instead of one reproduction number there now are four parameters. These make it possible to…

Populations and Evolution · Quantitative Biology 2020-10-05 Guus Balkema

Non-pharmaceutical interventions (NPIs) such as quarantine, self-isolation, social distancing, and virus-contact tracing can greatly reduce the spread of the virus during a pandemic. In the wave of the COVID-19 pandemic, many countries have…

Physics and Society · Physics 2020-12-16 Jingjing He , Xuefei Guan , Xiaochang Duan , Tian Shen , Jing Lin

To date, the only effective means to respond to the spreading of COVID-19 pandemic are non-pharmaceutical interventions (NPIs), which entail policies to reduce social activity and mobility restrictions. Quantifying their effect is…

Physics and Society · Physics 2021-03-01 Francesco Parino , Lorenzo Zino , Maurizio Porfiri , Alessandro Rizzo

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

In this work, we simulate the COVID-19 pandemic dynamics in a population modeled as a network of groups wherein infection can propagate both via intra-group and via inter-group interactions. Our results emphasize the importance of…

Physics and Society · Physics 2020-12-24 Ioan Baldea

Many of the control policies that were put into place during the Covid-19 pandemic had a common goal: to flatten the curve of the number of infected people so that its peak remains under a critical threshold. This letter considers the…

Systems and Control · Electrical Eng. & Systems 2020-11-26 Francesco Di Lauro , István Z. Kiss , Daniela Rus , Cosimo Della Santina

This paper considers the problem of designing non-pharmaceutical intervention (NPI) strategies, such as masking and social distancing, to slow the spread of a viral epidemic. We formulate the problem of jointly minimizing the infection…

Systems and Control · Electrical Eng. & Systems 2024-12-02 Shiyu Cheng , Luyao Niu , Bhaskar Ramasubramanian , Andrew Clark , Radha Poovendran

Various non pharmaceutical interventions have been settled to minimise the burden of the COVID-19 outbreak. We build a framework to analyse the dynamics of non pharmaceutical interventions, to distinguish between mitigations measures…

Populations and Evolution · Quantitative Biology 2023-01-23 Laurent Evain , Jean-Jacques Loeb

In the context of the recent COVID-19 outbreak, quarantine has been used to "flatten the curve" and slow the spread of the disease. In this paper, we show that this is not the only benefit of quarantine for the mitigation of an SIR epidemic…

Social and Information Networks · Computer Science 2021-02-23 Jessica Hoffmann , Matt Jordan , Constantine Caramanis

We propose a multi-layer network model for the spread of COVID-19 that accounts for interactions within the family, between schoolmates, and casual contacts in the population. We utilize the proposed model-calibrated on epidemiological and…

Physics and Society · Physics 2021-03-24 Christian Bongiorno , Lorenzo Zino

Non-pharmaceutical interventions have been critical in the fight against the COVID-19 pandemic. However, these sanitary measures have been partially lifted due to socioeconomic factors causing a worrisome rebound of the epidemic in several…

Populations and Evolution · Quantitative Biology 2021-02-23 Hugo Flores-Arguedas , José Ariel Camacho-Gutiérrez , Fernando Saldaña

Countries around the world implement nonpharmaceutical interventions (NPIs) to mitigate the spread of COVID-19. Design of efficient NPIs requires identification of the structure of the disease transmission network. We here identify the key…

Populations and Evolution · Quantitative Biology 2021-05-18 Simon Syga , Diana David-Rus , Yannik Schälte , Michael Meyer-Hermann , Haralampos Hatzikirou , Andreas Deutsch

The widespread, and in many countries unprecedented, use of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has highlighted the need for mathematical models which can estimate the impact of these measures while…

Nonpharmaceutical interventions (NPI) such as banning public events or instituting lockdowns have been widely applied around the world to control the current COVID-19 pandemic. Typically, this type of intervention is imposed when an…

Optimization and Control · Mathematics 2020-11-03 Carla Castillo-Laborde , Taco de Wolff , Pedro Gajardo , Rodrigo Lecaros , Gerard Olivar , Hector Ramirez C

Initial hopes of quickly eradicating the COVID-19 pandemic proved futile, and the goal shifted to controlling the peak of the infection, so as to minimize the load on healthcare systems. To that end, public health authorities intervened…

Optimization and Control · Mathematics 2021-05-25 M. Ali Al-Radhawi , Mahdiar Sadeghi , Eduardo D. Sontag

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

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