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Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Scattered Light Imaging (SLI) is a novel approach for microscopically revealing the fibre architecture of unstained brain sections. The measurements are obtained by illuminating brain sections from different angles and measuring the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Esteban Vaca , Miriam Menzel , Katrin Amunts , Markus Axer , Timo Dickscheid

Constrained Spherical Deconvolution (CSD) is widely used to estimate the white matter fiber orientation distribution (FOD) from diffusion MRI data. Its angular resolution depends on the maximum spherical harmonic order ($l_{max}$): low…

We propose two strategies to improve the quality of tractography results computed from diffusion weighted magnetic resonance imaging (DW-MRI) data. Both methods are based on the same PDE framework, defined in the coupled space of positions…

Computer Vision and Pattern Recognition · Computer Science 2017-02-08 J. M. Portegies , R. H. J. Fick , G. R. Sanguinetti , S. P. L. Meesters , G. Girard , R. Duits

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

Neurons and Cognition · Quantitative Biology 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

Fiber tracking based on diffusion weighted Magnetic Resonance Imaging (dMRI) allows for noninvasive reconstruction of fiber bundles in the human brain. In this chapter, we discuss sources of error and uncertainty in this technique, and…

Computer Vision and Pattern Recognition · Computer Science 2013-07-15 Thomas Schultz , Anna Vilanova , Ralph Brecheisen , Gordon Kindlmann

Our understanding of the human connectome is fundamentally limited by the resolution of diffusion MR images. Reconstructing a connectome's constituent neural pathways with tractography requires following a continuous field of fiber…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Tyler Spears , P. Thomas Fletcher

Inferring brain connectivity and structure \textit{in-vivo} requires accurate estimation of the orientation distribution function (ODF), which encodes key local tissue properties. However, estimating the ODF from diffusion MRI (dMRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 William Consagra , Lipeng Ning , Yogesh Rathi

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

Multi-compartment modeling of diffusion-weighted magnetic resonance imaging measurements is necessary for accurate brain connectivity analysis. Existing methods for estimating the number and orientations of fascicles in an imaging voxel…

Image and Video Processing · Electrical Eng. & Systems 2020-06-22 Davood Karimi , Lana Vasung , Camilo Jaimes , Fedel Machado-Rivas , Shadab Khan , Simon K. Warfield , Ali Gholipour

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Axel Elaldi , Neel Dey , Heejong Kim , Guido Gerig

Expansion of diffusion MRI (dMRI) both into the realm of strong gradients, and into accessible imaging with portable low-field devices, brings about the challenge of gradient nonlinearities. Spatial variations of the diffusion gradients…

We present an optimized algorithm for assigning fibers to targets in next-generation fiber-fed multi-object spectrographs. The method, that we named draining algorithm, ensures that the maximum number of targets in a given target field is…

Instrumentation and Methods for Astrophysics · Physics 2015-05-27 Isaac Morales , Antonio D. Montero-Dorta , Marco Azzaro , Francisco Prada , Justo Sanchez , Santiago Becerril

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

Applications · Statistics 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

An adaptive algorithm for computing eigenmodes and propagation constants of optical fibers is proposed. The algorithm is built using a dual-weighted residual error estimator. The residuals are based on the eigensystem for leaky hybrid modes…

Numerical Analysis · Mathematics 2024-08-28 Jay Gopalakrishnan , Jacob Grosek , Gabriel Pinochet-Soto , Pieter VandenBerge

Fibre orientation distribution (FOD) reconstruction using deep learning has the potential to produce accurate FODs from a reduced number of diffusion-weighted images (DWIs), decreasing total imaging time. Diffusion acquisition invariant…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 J Bartlett , C E Davey , L A Johnston , J Duan