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Due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) being a novel virus, there are currently no known effective antiviral drugs capable of slowing its progress. To accelerate the discovery of potential drug candidates,…

Biomolecules · Quantitative Biology 2020-09-29 Lokesh Agrawal , Thanasis Poullikkas , Scott Eisenhower , Carlo Monsanto , Ranjith Kumar Bakku

The coronavirus disease (COVID-19) has claimed the lives of over 350,000 people and infected more than 6 million people worldwide. Several search engines have surfaced to provide researchers with additional tools to find and retrieve…

The COVID-19 crisis called for rapid reaction from all the fields of biomedical research. Traditional drug development involves time consuming pipelines that conflict with the urgence of identifying effective therapies during a health and…

Genomics · Quantitative Biology 2020-05-06 Francesco Napolitano , Gennaro Gambardella , Diego Carrella , Xin Gao , Diego di Bernardo

The SARS-CoV-2 pandemic has created a global race for a cure. One approach focuses on designing a novel variant of the human angiotensin-converting enzyme 2 (ACE2) that binds more tightly to the SARS-CoV-2 spike protein and diverts it from…

Facing a global challenge with over 6.9 million fatalities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoViD-19, demands novel and comprehensive approaches to understand its complex dynamics. This…

Dynamical Systems · Mathematics 2023-06-05 João Paulo Simões Maurício de Carvalho

The great challenge for the humanity of the year 2020 is the fight against COVID-19. The whole world is making a huge effort to find an effective vaccine with purpose to protect people not yet infected. The alternative solution remains…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Mario Manzo , Simone Pellino

In the present study, we have described how by using molecular docking and molecular dynamic (MD) simulation studies the combination drug of ivermectin and doxycycline can be used as a potential inhibitor for SARS-CoV-2 virus. In lieu of…

Biological Physics · Physics 2020-12-02 Meenakshi Rana , Pooja , Papia Chowdhury

Drug repurposing can accelerate the identification of effective compounds for clinical use against SARS-CoV-2, with the advantage of pre-existing clinical safety data and an established supply chain. RNA viruses such as SARS-CoV-2…

The coronavirus (COVID-19) is currently the most common contagious disease which is prevalent all over the world. The main challenge of this disease is the primary diagnosis to prevent secondary infections and its spread from one person to…

COVID-19 has affected the world tremendously. It is critical that biological experiments and clinical designs are informed by computational approaches for time- and cost-effective solutions. Comparative analyses particularly can play a key…

Biomolecules · Quantitative Biology 2020-04-10 Goksel Misirli

With worldwide concerns surrounding the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), there is a rapidly growing body of literature on the virus. Clinicians, researchers, and policy-makers need a way to effectively search…

Information Retrieval · Computer Science 2020-08-04 Sean MacAvaney , Arman Cohan , Nazli Goharian

The issue of COVID-19, increasing with a massive mortality rate. This led to the WHO declaring it as a pandemic. In this situation, it is crucial to perform efficient and fast diagnosis. The reverse transcript polymerase chain reaction…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Lalith Bharadwaj B , Rohit Boddeda , Sai Vardhan K , Madhu G

Machine learning and deep learning play vital roles in predicting diseases in the medical field. Machine learning algorithms are widely classified as supervised, unsupervised, and reinforcement learning. This paper contains a detailed…

Machine Learning · Computer Science 2023-01-27 D. Kamelesun , R. Saranya , P. Kathiravan

This paper addresses the new problem of automated screening of coronavirus disease 2019 (COVID-19) based on chest X-rays, which is urgently demanded toward fast stopping the pandemic. However, robust and accurate screening of COVID-19 from…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Tianyang Li , Zhongyi Han , Benzheng Wei , Yuanjie Zheng , Yanfei Hong , Jinyu Cong

The outbreak of the novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been continuously affecting human lives and communities around the world in many ways, from cities…

Machine Learning · Computer Science 2020-07-24 Ashkan Ebadi , Pengcheng Xi , Stéphane Tremblay , Bruce Spencer , Raman Pall , Alexander Wong

The COVID-19 is sweeping the world with deadly consequences. Its contagious nature and clinical similarity to other pneumonias make separating subjects contracted with COVID-19 and non-COVID-19 viral pneumonia a priority and a challenge.…

Machine Learning · Computer Science 2020-05-15 Forrest Sheng Bao , Youbiao He , Jie Liu , Yuanfang Chen , Qian Li , Christina R. Zhang , Lei Han , Baoli Zhu , Yaorong Ge , Shi Chen , Ming Xu , Liu Ouyang

Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have compromised existing vaccines and posed a grand challenge to coronavirus disease 2019 (COVID-19) prevention, control, and global economic recovery. For…

Biomolecules · Quantitative Biology 2022-04-21 Jiahui Chen , Guo-Wei Wei

Recent advances in healthcare technologies have led to the availability of large amounts of biological samples across several techniques and applications. In particular, in the last few years, Raman spectroscopy analysis of biological…

Quantitative Methods · Quantitative Biology 2025-06-24 Marco Piazza , Andrea Spinelli , Francesca Maggioni , Marzia Bedoni , Enza Messina

We demonstrate use of iteratively pruned deep learning model ensembles for detecting pulmonary manifestation of COVID-19 with chest X-rays. This disease is caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Sivaramakrishnan Rajaraman , Jen Siegelman , Philip O. Alderson , Lucas S. Folio , Les R. Folio , Sameer K. Antani

SARS-CoV-2, the causative agent of COVID-19, remains a global health concern due to its high transmissibility and evolving variants. Although vaccination efforts and therapeutic advancements have mitigated disease severity, emerging…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Anjali Dharmik
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