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In recent years, advances in the development of whole-slide images have laid a foundation for the utilization of digital images in pathology. With the assistance of computer images analysis that automatically identifies tissue or cell…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jun Wang , Qianying Liu , Haotian Xie , Zhaogang Yang , Hefeng Zhou

In this paper, we introduce a simple, yet powerful pipeline for medical image segmentation that combines Fully Convolutional Networks (FCNs) with Fully Convolutional Residual Networks (FC-ResNets). We propose and examine a design that takes…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Michal Drozdzal , Gabriel Chartrand , Eugene Vorontsov , Lisa Di Jorio , An Tang , Adriana Romero , Yoshua Bengio , Chris Pal , Samuel Kadoury

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Brain tumor is considered as one of the deadliest and most common form of cancer both in children and in adults. Consequently, determining the correct type of brain tumor in early stages is of significant importance to devise a precise…

Computer Vision and Pattern Recognition · Computer Science 2018-03-05 Parnian Afshar , Arash Mohammadi , Konstantinos N. Plataniotis

Due to lack of annotated pathological images, transfer learning has been the predominant approach in the field of digital pathology.Pre-trained neural networks based on ImageNet database are often used to extract "off the shelf" features,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Xingyu Li , Min Cen , Jinfeng Xu , Hong Zhang , Xu Steven Xu

Advances in deep learning for natural images have prompted a surge of interest in applying similar techniques to medical images. The majority of the initial attempts focused on replacing the input of a deep convolutional neural network with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Krzysztof J. Geras , Stacey Wolfson , Yiqiu Shen , Nan Wu , S. Gene Kim , Eric Kim , Laura Heacock , Ujas Parikh , Linda Moy , Kyunghyun Cho

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Chest X-ray imaging is a critical diagnostic tool for identifying pulmonary diseases. However, manual interpretation of these images is time-consuming and error-prone. Automated systems utilizing convolutional neural networks (CNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2025-11-25 Saurabh Agarwal , K. V. Arya , Yogesh Kumar Meena

While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

Automatic detection of cancer metastasis from whole slide images (WSIs) is a crucial step for following patient staging and prognosis. Recent convolutional neural network based approaches are struggling with the trade-off between accuracy…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Zixu Zhao , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Early and accurate prediction of overall survival (OS) time can help to obtain better treatment planning for brain tumor patients. Although many OS time prediction methods have been developed and obtain promising results, there are still…

Image and Video Processing · Electrical Eng. & Systems 2020-07-16 Tao Zhou , Huazhu Fu , Yu Zhang , Changqing Zhang , Xiankai Lu , Jianbing Shen , Ling Shao

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Darvin Yi , Mu Zhou , Zhao Chen , Olivier Gevaert

In silico methods evaluating the mutation effects of missense mutations are providing an important approach for understanding mutations in personal genomes and identifying disease-relevant biomarkers. However, existing methods, including…

Quantitative Methods · Quantitative Biology 2024-06-14 Boshen Wang , Bowei Ye , Lin Xu , Jie Liang

Breast ultrasound (BUS) image segmentation plays a crucial role in a computer-aided diagnosis system, which is regarded as a useful tool to help increase the accuracy of breast cancer diagnosis. Recently, many deep learning methods have…

Image and Video Processing · Electrical Eng. & Systems 2020-03-24 Zhenyuan Ning , Ke Wang , Shengzhou Zhong , Qianjin Feng , Yu Zhang

Imaging-based early diagnosis of Alzheimer Disease (AD) has become an effective approach, especially by using nuclear medicine imaging techniques such as Positron Emission Topography (PET). In various literature it has been found that PET…

Machine Learning · Computer Science 2021-03-24 Jiaming Guo , Wei Qiu , Xiang Li , Xuandong Zhao , Ning Guo , Quanzheng Li

Breast cancer is one of the most common cancers among women globally, with early diagnosis and precise classification being crucial. With the advancement of deep learning and computer vision, the automatic classification of breast tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Jiacheng Hao , Yiqing Liu , Siqi Zeng , Yonghong He