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A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The…

Neurons and Cognition · Quantitative Biology 2017-05-09 Javier Rasero , Mario Pellicoro , Leonardo Angelini , Jesus M. Cortes , Daniele Marinazzo , Sebastiano Stramaglia

This paper brings together three distinct theories with the goal of quantifying shape textures with complex morphologies. Distance fields are central objects in shape representation, while topological data analysis uses algebraic topology…

Algebraic Topology · Mathematics 2023-07-04 Anna Song , Ka Man Yim , Anthea Monod

Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that…

Methodology · Statistics 2015-06-18 Brian P. Kent , Alessandro Rinaldo , Fang-Cheng Yeh , Timothy Verstynen

Geometric trees are characterized by their tree-structured layout and spatially constrained nodes and edges, which significantly impacts their topological attributes. This inherent hierarchical structure plays a crucial role in domains such…

Machine Learning · Computer Science 2024-08-19 Zheng Zhang , Allen Zhang , Ruth Nelson , Giorgio Ascoli , Liang Zhao

A communication network can be modeled as a directed connected graph with edge weights that characterize performance metrics such as loss and delay. Network tomography aims to infer these edge weights from their pathwise versions measured…

Optimization and Control · Mathematics 2019-08-12 Mahmood Ettehad , Nick Duffield , Gregory Berkolaiko

Two of the most useful tools in topological combinatorics are the nerve lemma and discrete Morse theory. In this note we introduce a theorem that interpolates between them and allows decompositions of complexes into non-contractible pieces…

Combinatorics · Mathematics 2013-07-18 Alexander Engström

Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

Methodology · Statistics 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

Topological data analysis combines machine learning with methods from algebraic topology. Persistent homology, a method to characterize topological features occurring in data at multiple scales is of particular interest. A major obstacle to…

Algebraic Topology · Mathematics 2019-04-25 Nello Blaser , Morten Brun

Merge trees are a type of topological descriptors that record the connectivity among the sublevel sets of scalar fields. They are among the most widely used topological tools in visualization. In this paper, we are interested in sketching a…

Computational Geometry · Computer Science 2021-06-01 Mingzhe Li , Sourabh Palande , Lin Yan , Bei Wang

Topological abstractions offer a method to summarize the behavior of vector fields but computing them robustly can be challenging due to numerical precision issues. One alternative is to represent the vector field using a discrete approach,…

Graphics · Computer Science 2025-12-09 Tanner Finken , Julien Tierny , Joshua A Levine

Many state-of-art neural models designed for monotonicity reasoning perform poorly on downward inference. To address this shortcoming, we developed an attentive tree-structured neural network. It consists of a tree-based…

Computation and Language · Computer Science 2021-01-05 Zeming Chen

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

In this paper, we study the induced homological sequence and the induced merge tree of a discrete Morse function on a tree. A discrete Morse function on a tree gives rise to a sequence of Betti numbers that keep track of the number of…

General Mathematics · Mathematics 2024-10-31 Nicholas A. Scoville , Dylan Wen

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

The parcellation of Cranial Nerves (CNs) serves as a crucial quantitative methodology for evaluating the morphological characteristics and anatomical pathways of specific CNs. Multi-modal CNs parcellation networks have achieved promising…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Lei Xie , Junxiong Huang , Yuanjing Feng , Qingrun Zeng

One of the critical steps in improving accurate single neuron reconstruction from three-dimensional (3D) optical microscope images is the neuronal structure segmentation. However, they are always hard to segment due to the lack in quality.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 Heng Wang , Yang Song , Chaoyi Zhang , Jianhui Yu , Siqi Liu , Hanchuan Peng , Weidong Cai

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Merge trees are a valuable tool in the scientific visualization of scalar fields; however, current methods for merge tree comparisons are computationally expensive, primarily due to the exhaustive matching between tree nodes. To address…

Machine Learning · Computer Science 2024-10-07 Yu Qin , Brittany Terese Fasy , Carola Wenk , Brian Summa