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Lung cancer is a significant cause of mortality worldwide, emphasizing the importance of early detection for improved survival rates. In this study, we propose a machine learning (ML) tool trained on data from the PLCO Cancer Screening…

Machine Learning · Computer Science 2023-08-24 Pierre-Louis Benveniste , Julie Alberge , Lei Xing , Jean-Emmanuel Bibault

Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most prevalent form of lung cancer. EGFR positive lung adenocarcinomas have been shown to have high response rates to TKI therapy, underlying the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Gabriele Campanella , David Ho , Ida Häggström , Anton S Becker , Jason Chang , Chad Vanderbilt , Thomas J Fuchs

Cancer is a fatal disease caused by a combination of genetic diseases and a variety of biochemical abnormalities. Lung and colon cancer have emerged as two of the leading causes of death and disability in humans. The histopathological…

Image and Video Processing · Electrical Eng. & Systems 2022-06-06 Md. Alamin Talukder , Md. Manowarul Islam , Md Ashraf Uddin , Arnisha Akhter , Khondokar Fida Hasan , Mohammad Ali Moni

Colorectal cancer (CRC) is the first cause of death in many countries. CRC originates from a small clump of cells on the lining of the colon called polyps, which over time might grow and become malignant. Early detection and removal of…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Truong Dang , Thanh Nguyen , John McCall , Alan Wee-Chung Liew

According to GHO (Global Health Observatory (GHO), the high prevalence of a large variety of diseases such as Ischaemic heart disease, stroke, lung cancer disease and lower respiratory infections have remained the top killers during the…

Artificial Intelligence · Computer Science 2020-09-17 Mayssa Ben Kahla , Dalel Kanzari , Ahmed Maalel

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

Nasopharyngeal Carcinoma (NPC) is endemic cancer in the south-east Asia. With the advent of intensity-modulated radiotherapy excellent locoregional control are being achieved. Consequently, this had led to pretreatment clinical staging…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Richard Du , Peng Cao , Lujun Han , Qiyong Ai , Ann D. King , Varut Vardhanabhuti

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer,…

Machine Learning · Statistics 2018-10-30 Siddhant Jain , Jalal Ziauddin , Paul Leonchyk , Joseph Geraci

Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply…

Genomics · Quantitative Biology 2026-04-22 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Humaira Gowher , Sabre Kais

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Bingxin Gong , Lian Yang , Junqing Yu , Wei Yang

At present, the incidence and fatality rate of lung cancer in China rank first among all malignant tumors. Despite the continuous development and improvement of China's medical level, the overall 5-year survival rate of lung cancer patients…

Medical Physics · Physics 2024-02-08 Shulin Li , Liqiang Yu , Bo Liu , Qunwei Lin , Jiaxin Huang

Purpose: This study evaluates the impact of harmonization and multi-region feature integration on survival prediction in non-small cell lung cancer (NSCLC) patients. We assess the prognostic utility of handcrafted radiomics and pretrained…

The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized…

Lung cancer is the deadliest type of cancer for both men and women. Feature selection plays a vital role in cancer classification. This paper investigates the feature selection process in Computed Tomographic (CT) lung cancer images using…

Machine Learning · Computer Science 2012-12-24 G. Jothi , H. Hannah Inbarani

The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muntasir Mamun , Md Ishtyaq Mahmud , Mahabuba Meherin , Ahmed Abdelgawad

Cancer is one of the leading causes of death in the developed world. Cancer diagnosis is performed through the microscopic analysis of a sample of suspicious tissue. This process is time consuming and error prone, but Deep Learning models…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Pedro Costa , Yongpan Fu , João Nunes , Aurélio Campilho , Jaime S. Cardoso

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup