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Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Automated skin lesion segmentation and classification are two most essential and related tasks in the computer-aided diagnosis of skin cancer. Despite their prevalence, deep learning models are usually designed for only one task, ignoring…

Computer Vision and Pattern Recognition · Computer Science 2020-02-13 Yutong Xie , Jianpeng Zhang , Yong Xia , Chunhua Shen

Training a Convolutional Neural Network (CNN) for semantic segmentation typically requires to collect a large amount of accurate pixel-level annotations, a hard and expensive task. In contrast, simple image tags are easier to gather. With…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Carolina Redondo-Cabrera , Marcos Baptista-Ríos , Roberto J. López-Sastre

Multi-scale deep CNNs have been used successfully for problems mapping each pixel to a label, such as depth estimation and semantic segmentation. It has also been shown that such architectures are reusable and can be used for multiple…

Computer Vision and Pattern Recognition · Computer Science 2016-09-21 Arsalan Mousavian , Hamed Pirsiavash , Jana Kosecka

Efficient and easy segmentation of images and volumes is of great practical importance. Segmentation problems that motivate our approach originate from microscopy imaging commonly used in materials science, medicine, and biology. We…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Vedrana Andersen Dahl , Monica Jane Emerson , Camilla Himmelstrup Trinderup , Anders Bjorholm Dahl

In computer vision, image segmentation is always selected as a major research topic by researchers. Due to its vital rule in image processing, there always arises the need of a better image segmentation method. Clustering is an unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2015-06-08 Dibya Jyoti Bora , Anil Kumar Gupta

Accurately segmenting and individualizing cells in SEM images is a highly promising technique for elucidating tissue architecture in oncology. While current AI-based methods are effective, errors persist, necessitating time-consuming manual…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Florian Robert , Alexia Calovoulos , Laurent Facq , Fanny Decoeur , Etienne Gontier , Christophe F. Grosset , Baudouin Denis de Senneville

Digital image watermarking is the process of embedding and extracting a watermark covertly on a cover-image. To dynamically adapt image watermarking algorithms, deep learning-based image watermarking schemes have attracted increased…

Multimedia · Computer Science 2020-07-07 Xin Zhong , Pei-Chi Huang , Spyridon Mastorakis , Frank Y. Shih

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

Recent advances in deep learning have enabled the development of automated frameworks for analysing medical images and signals, including analysis of cervical cancer. Many previous works focus on the analysis of isolated cervical cells, or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Ruiqi Wang , Mohammad Ali Armin , Simon Denman , Lars Petersson , David Ahmedt-Aristizabal

In this work we propose a novel approach to perform segmentation by leveraging the abstraction capabilities of convolutional neural networks (CNNs). Our method is based on Hough voting, a strategy that allows for fully automatic…

Well-performed deep neural networks (DNNs) generally require massive labelled data and computational resources for training. Various watermarking techniques are proposed to protect such intellectual properties (IPs), wherein the DNN…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Xiangyu Wen , Yu Li , Wei Jiang , Qiang Xu

Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Navid Alemi Koohababni , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

It is important to extract good features using an encoder to realize semantic segmentation with high accuracy. Although loss function is optimized in training deep neural network, far layers from the layers for computing loss function are…

Image and Video Processing · Electrical Eng. & Systems 2021-01-21 Takamasa Ando , Kazuhiro Hotta

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Deep convolutional neural networks (CNNs) have been intensively used for multi-class segmentation of data from different modalities and achieved state-of-the-art performances. However, a common problem when dealing with large, high…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Chengjia Wang , Tom MacGillivray , Gillian Macnaught , Guang Yang , David Newby

Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…

Applications · Statistics 2026-01-27 Laura Baracaldo , Blythe King , Haoran Yan , Yizi Lin , Nina Miolane , Mengyang Gu