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Graphical Gaussian models have proven to be useful tools for exploring network structures based on multivariate data. Applications to studies of gene expression have generated substantial interest in these models, and resulting recent…

Machine Learning · Computer Science 2014-08-12 Michael A. Finegold , Mathias Drton

Graphical models are ubiquitous tools to describe the interdependence between variables measured simultaneously such as large-scale gene or protein expression data. Gaussian graphical models (GGMs) are well-established tools for…

Methodology · Statistics 2020-01-09 Nilabja Guha , Veera Baladandayuthapani , Bani K. Mallick

The generalized inverse Gaussian, denoted $\mathrm{GIG}(p, a, b)$, is a flexible family of distributions that includes the gamma, inverse gamma, and inverse Gaussian distributions as special cases. In addition to its applications in…

Computation · Statistics 2025-01-28 Victor Peña , Michael Jauch

In this work we deal with correlated failure time (age at onset) data arising from population-based case-control studies, where case and control probands are selected by population-based sampling and an array of risk factor measures is…

Statistics Theory · Mathematics 2007-06-13 Malka Gorfine , David M. Zucker , Li Hsu

Bayesian inference for graphical models has received much attention in the literature in recent years. It is well known that when the graph G is decomposable, Bayesian inference is significantly more tractable than in the general…

Methodology · Statistics 2015-05-05 Kshitij Khare , Bala Rajaratnam , Abhishek Saha

We consider the problem of estimating multiple related but distinct graphical models on the basis of a high-dimensional data set with observations that belong to distinct classes. A motivating example occurs in the analysis of gene…

Methodology · Statistics 2012-07-12 Patrick Danaher , Pei Wang , Daniela M. Witten

In longitudinal observational studies with time-to-event outcomes, a common objective in causal analysis is to estimate the causal survival curve under hypothetical intervention scenarios. The g-formula is a useful tool for this analysis.…

Methodology · Statistics 2025-04-14 Xinyuan Chen , Liangyuan Hu , Fan Li

We propose a flexible formulation of the multivariate non-central skew t (NCST) distribution, defined by scaling skew-normal random vectors with independent chi-squared variables. This construction extends the classical multivariate t…

Methodology · Statistics 2025-07-15 Abeer M. Hasan , Ying-Ju Chen

The Generalized Linear Model (GLM) for the Gamma distribution (glmGamma) is widely used in modeling continuous, non-negative and positive-skewed data, such as insurance claims and survival data. However, model selection for GLM depends on…

Methodology · Statistics 2018-04-24 Xin Chen , Aleksandr Y. Aravkin , R. Douglas Martin

The autoregressive (AR) models are used to represent the time-varying random process in which output depends linearly on previous terms and a stochastic term (the innovation). In the classical version, the AR models are based on normal…

Methodology · Statistics 2021-11-15 Monika S. Dhull , Arun Kumar , Agnieszka Wylomanska

We introduce a general class of continuous univariate distributions with positive support obtained by transforming the class of two-piece distributions. We show that this class of distributions is very flexible, easy to implement, and…

Applications · Statistics 2015-11-06 Francisco J. Rubio , Yili Hong

Graphical Gaussian models have proven to be useful tools for exploring network structures based on multivariate data. Applications to studies of gene expression have generated substantial interest in these models, and resulting recent…

Methodology · Statistics 2011-08-10 Michael Finegold , Mathias Drton

We propose a large-margin Gaussian Mixture (L-GM) loss for deep neural networks in classification tasks. Different from the softmax cross-entropy loss, our proposal is established on the assumption that the deep features of the training set…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Weitao Wan , Yuanyi Zhong , Tianpeng Li , Jiansheng Chen

The multivariate adaptive regression spline (MARS) approach of Friedman (1991) and its Bayesian counterpart (Francom et al. 2018) are effective approaches for the emulation of computer models. The traditional assumption of Gaussian errors…

Methodology · Statistics 2024-07-23 Kellin Rumsey , Devin Francom , Andy Shen

Health economic evaluations often require predictions of survival rates beyond the follow-up period. Parametric survival models can be more convenient for economic modelling than the Cox model. The generalized gamma (GG) and generalized F…

Computation · Statistics 2022-07-13 Han Fu , Shahrul Mt-Isa , Richard Baumgartner , William Malbecq

Exponential family models, generalized linear models (GLMs), generalized linear mixed models (GLMMs) and generalized additive models (GAMs) are widely used methods in statistics. However, many scientific applications necessitate constraints…

Methodology · Statistics 2022-12-23 Benny Ren , Jeffrey Morris , Ian Barnett

Though Gaussian graphical models have been widely used in many scientific fields, relatively limited progress has been made to link graph structures to external covariates. We propose a Gaussian graphical regression model, which regresses…

Methodology · Statistics 2022-02-01 Jingfei Zhang , Yi Li

Frailty models are often the model of choice for heterogeneous survival data. A frailty model contains both random effects and fixed effects, with the random effects accommodating for the correlation in the data. Different estimation…

Methodology · Statistics 2019-09-17 Oodally Ajmal , Luc Duchateau , Estelle Kuhn

Beta regression has been extensively used by statisticians and practitioners to model bounded continuous data and there is no strong and similar competitor having its main features. A class of normalized inverse-Gaussian (N-IG) process was…

Methodology · Statistics 2020-03-12 Wagner Barreto-Souza , Vinícius D. Mayrink , Alexandre B. Simas

Foundation models (FMs) have transformed computational pathology by providing powerful, general-purpose feature extractors. However, adapting and benchmarking individual FMs for specific diagnostic tasks is often time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Peiran Quan , Zifan Gu , Zhuo Zhao , Qin Zhou , Donghan M. Yang , Ruichen Rong , Yang Xie , Guanghua Xiao