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This paper presents a method for computing a least fixpoint of a system of equations over booleans. The resulting computation can be significantly shorter than the result of iteratively evaluating the entire system until a fixpoint is…

Programming Languages · Computer Science 2007-05-23 Viktor Kuncak , K. Rustan M. Leino

We present a computational method for finding attractors (ergodic sets of states) of Boolean networks under asynchronous update. The approach is based on a systematic removal of state transitions to render the state transition graph…

Disordered Systems and Neural Networks · Physics 2010-08-24 Thomas Skodawessely , Konstantin Klemm

Dynamical systems theory and complexity science provide powerful tools for analysing artificial agents and robots. Furthermore, they have been recently proposed also as a source of design principles and guidelines. Boolean networks are a…

Artificial Intelligence · Computer Science 2015-03-18 Andrea Roli , Mattia Manfroni , Carlo Pinciroli , Mauro Birattari

Interaction graphs provide an important qualitative modeling approach for System Biology. This paper presents a novel approach for construction of interaction graph with the help of Boolean function decomposition. Each decomposition part…

Systems and Control · Computer Science 2014-09-26 Jayanta Kumar Das , Ranjeet Kumar Rout , Pabitra Pal Choudhury

The aim of this paper is to analyze a class of consensus algorithms with finite-time or fixed-time convergence for dynamic networks formed by agents with first-order dynamics. In particular, in the analyzed class a single evaluation of a…

Boolean networks are one of the most studied discrete models in the context of the study of gene expression. In order to define the dynamics associated to a Boolean network, there are several \emph{update schemes} that range from parallel…

Formal Languages and Automata Theory · Computer Science 2019-01-29 Eric Goles , Pedro Montealegre , Martín Ríos Wilson

Many systems of interacting elements can be conceptualized as networks, where network nodes represent the elements and network ties represent interactions between the elements. In systems where the underlying network evolves in time, it is…

Methodology · Statistics 2015-05-05 Ian Barnett , Jukka-Pekka Onnela

We use fixed point theory to analyze nonnegative neural networks, which we define as neural networks that map nonnegative vectors to nonnegative vectors. We first show that nonnegative neural networks with nonnegative weights and biases can…

Machine Learning · Statistics 2024-06-18 Tomasz J. Piotrowski , Renato L. G. Cavalcante , Mateusz Gabor

Boolean automata networks (aka Boolean networks) are space-time discrete dynamical systems, studied as a model of computation and as a representative model of natural phenomena. A collection of simple entities (the automata) update their…

Discrete Mathematics · Computer Science 2024-02-12 Kévin Perrot , Sylvain Sené , Léah Tapin

Boolean networks may be viewed as idealizations of biological genetic networks, where each node is represented by an on-off switch which is a function of the binary output from some other nodes. We evolve connectivity in a single Boolean…

Biological Physics · Physics 2016-09-08 Stefan Bornholdt , Kim Sneppen

The simple greedy algorithm to find a maximal independent set of a graph can be viewed as a sequential update of a Boolean network, where the update function at each vertex is the conjunction of all the negated variables in its…

Discrete Mathematics · Computer Science 2023-07-12 Maximilien Gadouleau , David C. Kutner

This paper proposes a new parameter for studying Boolean networks: the independence number. We establish that a Boolean network is $k$-independent if, for any set of $k$ variables and any combination of binary values assigned to them, there…

Combinatorics · Mathematics 2024-10-08 Julio Aracena , Raúl Astete-Elguin

Our daily social and political life is more and more impacted by social networks. The functioning of our living bodies is deeply dependent on biological regulation networks such as neural, genetic, and protein networks. And the physical…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Tarek Melliti , Mathilde Noual , Damien Regnault , Sylvain Sené

This paper addresses the problem of finding cycles in the state transition graphs of synchronous Boolean networks. Synchronous Boolean networks are a class of deterministic finite state machines which are used for the modeling of gene…

Molecular Networks · Quantitative Biology 2009-01-29 Elena Dubrova , Maxim Teslenko

The generating functional method is employed to investigate the synchronous dynamics of Boolean networks, providing an exact result for the system dynamics via a set of macroscopic order parameters. The topology of the networks studied and…

Disordered Systems and Neural Networks · Physics 2015-05-28 Alexander Mozeika , David Saad

Fixed-parameter algorithms and kernelization are two powerful methods to solve $\mathsf{NP}$-hard problems. Yet, so far those algorithms have been largely restricted to static inputs. In this paper we provide fixed-parameter algorithms and…

Data Structures and Algorithms · Computer Science 2017-07-04 Josh Alman , Matthias Mnich , Virginia Vassilevska Williams

Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…

Molecular Networks · Quantitative Biology 2013-06-14 Jorge G. T. Zañudo , Réka Albert

Human decisional processes result from the employment of selected quantities of relevant information, generally synthesized from environmental incoming data and stored memories. Their main goal is the production of an appropriate and…

Artificial Intelligence · Computer Science 2016-09-08 Graziano Barnabei , Franco Bagnoli , Ciro Conversano , Elena Lensi

For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems. In this work, we propose a novel…

Adaptation and Self-Organizing Systems · Physics 2009-09-30 Christian Darabos , Marco Tomassini , Mario Giacobini

Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system's dynamical behavior, for example, detecting key therapeutic targets to control pathways in models of…

Physics and Society · Physics 2023-11-02 Thomas Parmer , Filippo Radicchi