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Population structure can have a significant effect on evolution. For some systems with sufficient symmetry, analytic results can be derived within the mathematical framework of evolutionary graph theory which relate to the outcome of the…

Populations and Evolution · Quantitative Biology 2019-03-11 Christopher E. Overton , Mark Broom , Christoforos Hadjichrysanthou , Kieran J. Sharkey

Information of 1.6 million patients identified as SARS-CoV-2 positive in Mexico is used to understand the relationship between comorbidities, symptoms, hospitalizations and deaths due to the COVID-19 disease. Using the presence or absence…

Applications · Statistics 2024-06-17 Carlos E. Rodríguez , Ramsés H. Mena

We apply topological data analysis, specifically the Mapper algorithm, to the U.S. COVID-19 data. The resulting Mapper graphs provide visualizations of the pandemic that are more complete than those supplied by other, more standard methods.…

Populations and Evolution · Quantitative Biology 2021-09-15 Yiran Chen , Ismar Volic

A stochastic epidemic model accounting for the effect of contact-tracing on the spread of an infectious disease is studied. Precisely, individuals identified as infected may contribute to detecting other infectious individuals by providing…

Probability · Mathematics 2009-03-28 Stéphan Clémençon , Viet Chi Tran , Hector De Arazoza

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

We consider real-time timely tracking of infection status (e.g., covid-19) of individuals in a population. In this work, a health care provider wants to detect infected people as well as people who have recovered from the disease as quickly…

Information Theory · Computer Science 2022-06-15 Melih Bastopcu , Sennur Ulukus

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…

Applications · Statistics 2020-10-30 Philip Nadler , Shuo Wang , Rossella Arcucci , Xian Yang , Yike Guo

Social distancing has been the only effective way to contain the spread of an infectious disease prior to the availability of the pharmaceutical treatment. It can lower the infection rate of the disease at the economic cost. A pandemic…

Applications · Statistics 2020-12-07 Kexin Chen , Chi Seng Pun , Hoi Ying Wong

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

Quantitative Methods · Quantitative Biology 2021-03-18 Vincent Brault , Bastien Mallein , Jean-Francois Rupprecht

Mathematical modeling has been fundamental to achieving near real-time accurate forecasts of the spread of COVID-19. Similarly, the design of non-pharmaceutical interventions has played a key role in the application of policies to contain…

Physics and Society · Physics 2023-04-04 Jorge P. Rodríguez , Alberto Aleta , Yamir Moreno

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

We present a general framework for using existing data to estimate the efficiency gain from using a covariate-adjusted estimator of a marginal treatment effect in a future randomized trial. We describe conditions under which it is possible…

Methodology · Statistics 2021-05-03 Xiudi Li , Sijia Li , Alex Luedtke

Given its wide-ranging and long-lasting impacts, COVID-19, especially its spatial spreading dynamics has received much attention. Knowledge of such dynamics helps public health professionals and city managers devise and deploy efficient…

Social and Information Networks · Computer Science 2022-10-04 Jiali Zhou , Zhan Zhao , Jiangping Zhou

Having accurate and timely data on confirmed active COVID-19 cases is challenging, since it depends on testing capacity and the availability of an appropriate infrastructure to perform tests and aggregate their results. In this paper, we…

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

Applications · Statistics 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

Other Quantitative Biology · Quantitative Biology 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter

COVID-19 has challenged health systems to learn how to learn. This paper describes the context, methods and challenges for learning to improve COVID-19 care at one academic health center. Challenges to learning include: (1) choosing a right…

In this paper we develop a SIR epidemiological model with parameters calculated according to existing data at the time of writing (24/03/2020); the data is from Italy, South Korea and Colombia, the model is then used to project the…

Populations and Evolution · Quantitative Biology 2020-09-28 Carlos Armando De Castro

We consider methods for transporting a prediction model and assessing its performance for use in a new target population, when outcome and covariate information for model development is available from a simple random sample from the source…

Applications · Statistics 2021-04-15 Jon A. Steingrimsson , Constantine Gatsonis , Issa J. Dahabreh
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