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Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

This paper presents a systematic overview of parameter-efficient fine-tuning methods, covering over 50 papers published between early 2019 and mid-2024. These methods aim to address the challenges of fine-tuning large language models by…

Computation and Language · Computer Science 2024-11-25 Vladislav Lialin , Vijeta Deshpande , Xiaowei Yao , Anna Rumshisky

Many universities have courses and projects revolving around compiler or interpreter implementation as part of their degree programmes in computer science. In such teaching activities, tool support can be highly beneficial. While there are…

Programming Languages · Computer Science 2022-09-21 Georgian-Vlad Saioc , Hans Hüttel

The Active Matter Evaluation Package (AMEP) is a Python library for analyzing simulation data of particle-based and continuum simulations. It provides a powerful and simple interface for handling large data sets and for calculating and…

Data curation presents a challenge to all scientific disciplines to ensure public availability and reproducibility of experimental data. Standards for data preservation and exchange are central to addressing this challenge: the…

Biomolecules · Quantitative Biology 2016-02-16 Chase P. Dowling , Elizabeth Jurrus , Sylvia Johnson , Nathan A. Baker

Representation learning for protein biochemical space faces a difficult trade-off: protein language models excel at capturing long-range biological semantics but often miss fine-grained chemical details. Conversely, chemical language models…

Biomolecules · Quantitative Biology 2026-03-03 Chunbin Gu , Zijun Gao , Mutian He , Jingjie Zhang , Haipeng Wen , Zihao Luo , Xiaorui Wang , Hanqun Cao , Jiajun Bu , Chang-Yu Hsieh , Pheng Ann Heng

Chat models are capable of answering a wide range of questions, however, the accuracy of their responses is highly uncertain. In this research, we propose a specialized PEFT-MedAware model where we utilize parameter-efficient fine-tuning…

Computation and Language · Computer Science 2023-11-20 Keivalya Pandya

Parameter identifiability describes whether, for a given differential model, one can determine parameter values from model equations. Knowing global or local identifiability properties allows construction of better practical experiments to…

Mathematical Software · Computer Science 2021-07-02 Ilia Ilmer , Alexey Ovchinnikov , Gleb Pogudin

Recently, extensive deep learning architectures and pretraining strategies have been explored to support downstream protein applications. Additionally, domain-specific models incorporating biological knowledge have been developed to enhance…

Biomolecules · Quantitative Biology 2026-03-03 Shuo Yan , Yuliang Yan , Bin Ma , Chenao Li , Haochun Tang , Jiahua Lu , Minhua Lin , Yuyuan Feng , Enyan Dai

The structural identifiability and the observability of a model determine the possibility of inferring its parameters and states by observing its outputs. These properties should be analysed before attempting to calibrate a model.…

Systems and Control · Electrical Eng. & Systems 2022-10-18 Xabier Rey Barreiro , Alejandro F. Villaverde

A program can be viewed as a syntactic structure P (syntactic skeleton) parameterized by a collection of the identifiers V (variable names). This paper introduces the skeletal program enumeration (SPE) problem: Given a fixed syntactic…

Programming Languages · Computer Science 2017-07-13 Qirun Zhang , Chengnian Sun , Zhendong Su

With the continuous growth in the number of parameters of transformer-based pretrained language models (PLMs), particularly the emergence of large language models (LLMs) with billions of parameters, many natural language processing (NLP)…

Computation and Language · Computer Science 2023-12-20 Lingling Xu , Haoran Xie , Si-Zhao Joe Qin , Xiaohui Tao , Fu Lee Wang

In this work we introduce repro_eval - a tool for reactive reproducibility studies of system-oriented information retrieval (IR) experiments. The corresponding Python package provides IR researchers with measures for different levels of…

Information Retrieval · Computer Science 2022-01-20 Timo Breuer , Nicola Ferro , Maria Maistro , Philipp Schaer

We develop Process Execution Graphs (PEG), a document-level representation of real-world wet lab biochemistry protocols, addressing challenges such as cross-sentence relations, long-range coreference, grounding, and implicit arguments. We…

Computation and Language · Computer Science 2021-04-15 Ronen Tamari , Fan Bai , Alan Ritter , Gabriel Stanovsky

Automation is becoming ubiquitous in all laboratory activities, leading towards precisely defined and codified laboratory protocols. However, the integration between laboratory protocols and mathematical models is still lacking. Models…

Quantitative Methods · Quantitative Biology 2021-11-30 Luca Cardelli , Marta Kwiatkowska , Luca Laurenti

The specification of requirements and tests are crucial activities in automotive development projects. However, due to the increasing complexity of automotive systems, practitioners fail to specify requirements and tests for distributed and…

Many theoretical works and tools on epidemiological field reflect the emphasis on decision-making Tools by both public health and the scientific community, which continues to increase. Indeed, in the epidemiological field, modeling tools…

Computational Engineering, Finance, and Science · Computer Science 2013-11-18 Dalila Hamami , Baghdad Atmani

Parameter-efficient fine-tuning (PEFT) has emerged as an effective method for adapting pre-trained language models to various tasks efficiently. Recently, there has been a growing interest in transferring knowledge from one or multiple…

Computation and Language · Computer Science 2024-06-07 Zhisheng Lin , Han Fu , Chenghao Liu , Zhuo Li , Jianling Sun

Reliable parameter extraction from experimental data is central to quantitative analysis in spectroscopy, diffraction, photoluminescence, chromatography, microscopy, and time-resolved measurements. We present FitED, a Python-based desktop…

Data Analysis, Statistics and Probability · Physics 2026-05-04 Mustafa Mahmoud Aboulsaad

Various networks are broadly and deeply applied in real-life applications. Reliability is the most important index for measuring the performance of all network types. Among the various algorithms, only implicit enumeration algorithms, such…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-21 Wei-Chang Yeh