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Biological flow networks adapt their network morphology to optimise flow while being exposed to external stimuli from different spatial locations in their environment. These adaptive flow networks retain a memory of the stimulus location in…

Soft Condensed Matter · Physics 2023-04-12 Komal Bhattacharyya , David Zwicker , Karen Alim

What is the physiological basis of long-term memory? The prevailing view in neuroscience attributes changes in synaptic efficacy to memory acquisition. This view implies that stable memories correspond to stable connectivity patterns.…

Neurons and Cognition · Quantitative Biology 2019-10-09 Lee Susman , Naama Brenner , Omri Barak

Neural networks suffer from catastrophic forgetting and are unable to sequentially learn new tasks without guaranteed stationarity in data distribution. Continual learning could be achieved via replay -- by concurrently training externally…

Cortical networks can maintain memories for decades despite the short lifetime of synaptic strength. Can a neural network store long-lasting memories in unstable synapses? Here, we study the effects of random noise on the stability of…

Neurons and Cognition · Quantitative Biology 2012-06-01 Yi Wei , Alexei A. Koulakov

We introduce a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study neutral drift in networks that yield oscillatory dynamics. Starting with a…

Molecular Networks · Quantitative Biology 2018-04-25 Md. Zulfikar Ali , Ned S. Wingreen , Ranjan Mukhopadhyay

Humans and animals learn throughout life. Such continual learning is crucial for intelligence. In this chapter, we examine the pivotal role plasticity mechanisms with complex internal synaptic dynamics could play in enabling this ability in…

Neurons and Cognition · Quantitative Biology 2024-10-21 Friedemann Zenke , Axel Laborieux

Efficient continual learning in humans is enabled by a rich set of neurophysiological mechanisms and interactions between multiple memory systems. The brain efficiently encodes information in non-overlapping sparse codes, which facilitates…

Neural and Evolutionary Computing · Computer Science 2023-01-13 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Continuous, adaptive learning, the ability to adapt to the environment and keep improving performance, is a hallmark of natural intelligence. Biological organisms excel in acquiring, transferring, and retaining knowledge while adapting to…

Neurons and Cognition · Quantitative Biology 2026-03-03 Jie Mei , Alejandro Rodriguez-Garcia , Daigo Takeuchi , Gabriel Wainstein , Nina Hubig , Yalda Mohsenzadeh , Srikanth Ramaswamy

Progress has led to a detailed understanding of the neural mechanisms that underlie decision making in primates. However, less is known about why such mechanisms are present in the first place. Theory suggests that primate decision making…

Neurons and Cognition · Quantitative Biology 2026-01-21 Nathan J. Wispinski , Scott A. Stone , Anthony Singhal , Patrick M. Pilarski , Craig S. Chapman

Understanding the internal dynamics of Recurrent Neural Networks (RNNs) is crucial for advancing their interpretability and improving their design. This study introduces an innovative information-theoretic method to identify and analyze…

Machine Learning · Computer Science 2025-10-03 Arend Hintze , Asadullah Najam , Jory Schossau

We report short-term memory formation in a nonlinear dynamical system with many degrees of freedom. The system ``remembers'' a sequence of impulses for a transient period, but it coarsens and eventually ``forgets'' nearly all of them. The…

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

Neurons and Cognition · Quantitative Biology 2017-06-16 Stefano Fusi

We extend recurrent neural networks to include several flexible timescales for each dimension of their output, which mechanically improves their abilities to account for processes with long memory or with highly disparate time scales. We…

Statistical Finance · Quantitative Finance 2023-08-21 Damien Challet , Vincent Ragel

Learning or memory formation are associated with the strengthening of the synaptic connections between neurons according to a pattern reflected by the input. According to this theory a retained memory sequence is associated to a dynamic…

Dynamical Systems · Mathematics 2016-03-23 Pascal Chossat , Martin Krupa

Neurons with internal memory have been proposed for biological and bio-inspired neural networks, adding interesting functionality. We propose and model a nanoscale optoelectronic neural node with charge-based time-limited memory and signal…

Applied Physics · Physics 2023-09-22 David Winge , Magnus Borgström , Erik Lind , Anders Mikkelsen

Recurrent neural networks (RNNs) are widely used throughout neuroscience as models of local neural activity. Many properties of single RNNs are well characterized theoretically, but experimental neuroscience has moved in the direction of…

Machine Learning · Computer Science 2023-01-31 Leo Kozachkov , Michaela Ennis , Jean-Jacques Slotine

Heterogeneity is a ubiquitous property of many biological systems and has profound implications for computation. While it is conceivable to optimize neuronal and synaptic heterogeneity for a specific task, such top-down optimization is…

Machine Learning · Computer Science 2025-12-02 Arash Golmohammadi , Jannik Luboeinski , Christian Tetzlaff

The effects of noise on memory in a linear recurrent network are theoretically investigated. Memory is characterized by its ability to store previous inputs in its instantaneous state of network, which receives a correlated or uncorrelated…

Neural and Evolutionary Computing · Computer Science 2025-10-02 JingChuan Guan , Tomoyuki Kubota , Yasuo Kuniyoshi , Kohei Nakajima

Biological visual systems exhibit abundant recurrent connectivity. State-of-the-art neural network models for visual recognition, by contrast, rely heavily or exclusively on feedforward computation. Any finite-time recurrent neural network…

Neurons and Cognition · Quantitative Biology 2020-12-09 Ruben S. van Bergen , Nikolaus Kriegeskorte

Backpropagation-optimized artificial neural networks, while precise, lack robustness, leading to unforeseen behaviors that affect their safety. Biological neural systems do solve some of these issues already. Unlike artificial models,…

Neural and Evolutionary Computing · Computer Science 2025-02-04 Konstantin Holzhausen , Mia Merlid , Håkon Olav Torvik , Anders Malthe-Sørenssen , Mikkel Elle Lepperød