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Modeling and control of epidemics such as the novel Corona virus have assumed paramount importance at a global level. A natural and powerful dynamical modeling framework to use in this context is a continuous time Markov decision process…

Physics and Society · Physics 2023-04-13 Amal Roy , Chandramani Singh , Y. Narahari

In this chapter, we focus on the problem of containing the spread of diseases taking place in both temporal and adaptive networks (i.e., networks whose structure `adapts' to the state of the disease). We specifically focus on the problem of…

Social and Information Networks · Computer Science 2019-03-19 Masaki Ogura , Victor M. Preciado

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Nonlinear mixed effects models have received a great deal of attention in the statistical literature in recent years because of their flexibility in handling longitudinal studies, including human immunodeficiency virus viral dynamics,…

Methodology · Statistics 2021-09-28 Fernanda L. Schumacher , Dipak K. Dey , Victor H. Lachos

In this paper, we propose Total Variation Regularized Tensor-on-scalar Regression(TVTR), a novel method for estimating the association between a tensor outcome (a one dimensional or multidimensional array) and scalar predictors. While the…

Methodology · Statistics 2018-12-11 Ying Liu , Bowei Yan , Kathleen Merikangas , Haochang Shou

The COVID-19 pandemic highlighted the need to improve the modeling, estimation, and prediction of how infectious diseases spread. SEIR-like models have been particularly successful in providing accurate short-term predictions. This study…

Populations and Evolution · Quantitative Biology 2024-12-31 Jorge P. Zubelli , Jennifer Loria , Vinicius V. L. Albani

Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…

Populations and Evolution · Quantitative Biology 2024-09-09 Ning Jiang , Weiqi Chu , Yao Li

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

We present a general framework for adaptive allocation of viral tests in social contact networks. We pose and solve several complementary problems. First, we consider the design of a social sensing system whose objective is the early…

Social and Information Networks · Computer Science 2020-11-05 Pau Batlle , Joan Bruna , Carlos Fernandez-Granda , Victor M. Preciado

In this paper, we address a social planner's optimal control problem for a partially observable stochastic epidemic model. The control measures include social distancing, testing, and vaccination. Using a diffusion approximation for the…

Optimization and Control · Mathematics 2025-03-11 Ibrahim Mbouandi Njiasse , Florent Ouabo Kamkumo , Ralf Wunderlich

Since the beginning of the epidemic, daily reports of CoViD-19 cases, hospitalizations, and deaths from around the world have been publicly available. This paper describes methods to characterize broad features of the spread of the disease,…

Physics and Society · Physics 2020-07-15 Dean Karlen

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

Time-to-event models are a popular tool to analyse data where the outcome variable is the time to the occurrence of a specific event of interest. Here we focus on the analysis of time-to-event outcomes that are either intrisically discrete…

Applications · Statistics 2017-04-14 Moritz Berger , Matthias Schmid

In this paper, we propose the Graph-Fused Multivariate Regression (GFMR) via Total Variation regularization, a novel method for estimating the association between a one-dimensional or multidimensional array outcome and scalar predictors.…

Methodology · Statistics 2020-01-15 Ying Liu , Bowei Yan , Kathleen Merikangas , Haochang Shou

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

In this work, we introduce a quantum-inspired epidemic model to study the dynamics of an infectious disease in a population divided into compartments. By treating the healthy population as a large reservoir, we construct a framework based…

Populations and Evolution · Quantitative Biology 2025-03-19 Fabio Bagarello , Francesco Gargano , Polina Khrennikova

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

Deterministic compartmental models are predominantly used in the modeling of infectious diseases, though stochastic models are considered more realistic, yet are complicated to estimate due to missing data. In this paper we present a novel…

Computation · Statistics 2022-06-22 Shuying Wang , Stephen G. Walker

Generalization methods offer a powerful solution to one of the key drawbacks of randomized controlled trials (RCTs): their limited representativeness. By enabling the transport of treatment effect estimates to target populations subject to…

Methodology · Statistics 2025-05-20 Ahmed Boughdiri , Clément Berenfeld , Julie Josse , Erwan Scornet

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

Populations and Evolution · Quantitative Biology 2023-05-31 Sei Zhen Khong , Lanlan Su