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In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher , Taylor A. Kessinger , Boris I. Shraiman

We study the stationary state of a population evolving under the action of random genetic drift, selection and recombination in which both deleterious and reverse beneficial mutations can occur. We find that the equilibrium fraction of…

Populations and Evolution · Quantitative Biology 2016-01-13 Sona John , Kavita Jain

Seed banks are a common characteristics to many plant species, which allow storage of genetic diversity in the soil as dormant seeds for various periods of time. We investigate an above-ground population following a Fisher-Wright model with…

Populations and Evolution · Quantitative Biology 2017-01-13 Bendix Koopmann , Johannes Müller , Aurélien Tellier , Daniel Živković

We consider a model for Darwinian evolution in an asexual population with a large but non-constant populations size characterized by a natural birth rate, a logistic death rate modelling competition and a probability of mutation at each…

Probability · Mathematics 2015-08-28 Martina Baar , Anton Bovier , Nicolas Champagnat

We consider a system of two stochastic differential equations (SDEs) with competing two-way interactions driven by Brownian motions and spectrally positive $\alpha$-stable random measures. Such a SDE system can be identified as a…

Probability · Mathematics 2026-03-09 Jie Xiong , Xu Yang , Xiaowen Zhou

Understanding patterns of selectively neutral genetic variation is essential in order to model deviations from neutrality, caused for example by different forms of selection. Best understood is neutral genetic variation at a single locus,…

Populations and Evolution · Quantitative Biology 2012-06-13 E. Schaper , A. Eriksson , M. Rafajlovic , S. Sagitov , B. Mehlig

We study numerically and analytically a stochastic group selection model in which a population of asexually reproducing individuals, each of which can be either altruist or non-altruist, is subdivided into $M$ reproductively isolated groups…

adap-org · Physics 2009-10-31 Ana T. C. Silva , J. F. Fontanari

Non-African populations have experienced major bottlenecks in the time since their split from West Africans, which has led to the hypothesis that natural selection to remove weakly deleterious mutations may have been less effective in…

Populations and Evolution · Quantitative Biology 2014-02-21 Ron Do , Daniel Balick , Heng Li , Ivan Adzhubei , Shamil Sunyaev , David Reich

We introduce a general diploid population model with self-fertilization and possible overlapping generations, and study the genealogy of a sample of $n$ genes as the population size $N$ tends to infinity. Unlike traditional approach in…

Probability · Mathematics 2026-01-01 Louis Wai-Tong Fan , Maximillian Newman , John Wakeley

Kingman's model of selection and mutation studies the limit type value distribution in an asexual population of discrete generations and infinite size undergoing selection and mutation. This paper generalizes the model to analyse the…

Probability · Mathematics 2016-09-21 Linglong Yuan

The Moran discrete process and the Wright-Fisher modelare the most popular models in population genetics. It is common tounderstand the dynamics of these models to use an approximating diffusionprocess, called Wright-Fisher diffusion. Here,…

Probability · Mathematics 2019-05-13 Gorgui Gackou , A Guillin , Arnaud Personne

We study a class of evolution models, where the breeding process involves an arbitrary exchangeable process, allowing for mutations to appear. The population size $n$ is fixed, hence after breeding, selection is applied. Individuals are…

Probability · Mathematics 2022-05-03 Daniela Bertacchi , Juri Lember , Fabio Zucca

The propagation of a beneficial mutation in a spatially extended population is usually studied using the phenomenological stochastic Fisher-Kolmogorov (SFKPP) equation. We derive here an individual based, stochastic model founded on the…

Biological Physics · Physics 2017-08-02 Bahram Houchmandzadeh , Marcel Vallade

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing

We establish a genealogical framework for an existing analytical moment duality between a Wright--Fisher type SDE and a counting process with interaction. To achieve this, we construct a finite-population Moran model featuring interactive…

Probability · Mathematics 2026-05-05 Ellen Baake , Fernando Cordero , Hannah Dopmeyer

To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare. But if…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher

For a population with any given number of types, we construct a new multivariate Moran process with frequency-dependent selection and establish, analytically, a correspondence to equilibrium Lotka-Volterra phenomenology. This…

Populations and Evolution · Quantitative Biology 2015-05-30 Andrew E. Noble , Alan Hastings , William F. Fagan

We revisit the classical population genetics model of a population evolving under multiplicative selection, mutation and drift. The number of beneficial alleles in a multi-locus system can be considered a trait under exponential selection.…

adap-org · Physics 2007-05-23 Magnus Rattray , Jonathan L. Shapiro

The Moran process is a classic stochastic process that models the rise and takeover of novel traits in network-structured populations. In biological terms, a set of mutants, each with fitness $m\in(0,\infty)$ invade a population of…

Data Structures and Algorithms · Computer Science 2024-05-14 Petros Petsinis , Andreas Pavlogiannis , Josef Tkadlec , Panagiotis Karras

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

Probability · Mathematics 2014-07-30 G. Achaz , C. Delaporte , A. Lambert
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