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The transport of energy inside protein $\alpha$-helices is studied by deriving a system of quantum equations of motion from the Davydov Hamiltonian with the use of the Schr\"odinger equation and the generalized Ehrenfest theorem.…

Soft Condensed Matter · Physics 2018-11-26 Danko D. Georgiev , James F. Glazebrook

Protein clamps provide the cell with effective mechanisms for sensing of environmental changes and triggering adaptations that maintain homeostasis. The general physical mechanism behind protein clamping action, however, is poorly…

Biological Physics · Physics 2019-04-23 Danko D. Georgiev , James F. Glazebrook

Biological order provided by $\alpha$-helical secondary protein structures is an important resource exploitable by living organisms for increasing the efficiency of energy transport. In particular, self-trapping of amide I energy quanta by…

Pattern Formation and Solitons · Physics 2020-07-02 Danko D. Georgiev , James F. Glazebrook

Protein$\alpha$-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of…

Biological Physics · Physics 2022-02-02 Danko D. Georgiev , James F. Glazebrook

We consider the Davydov model of {\alpha}-helix protein chain with both exciton-exciton and excitonphonon couplings and investigate on the evolution of elliptic solitons. In the discrete regime of the adiabatic limit, we analytically and…

Pattern Formation and Solitons · Physics 2023-05-15 Nkeh Oma Nfor , Michael Nana Jipdi

Transport of excitations along proteins can be formulated in a quantum physics context, based on the periodicity and vibrational modes of the structures. Exact solutions are very challenging to obtain on classical computers, however,…

Atomic Physics · Physics 2018-06-22 Marcin Płodzień , Tomasz Sowiński , Servaas Kokkelmans

Macromolecular protein complexes catalyze essential physiological processes that sustain life. Various interactions between protein subunits could increase the effective mass of certain peptide groups, thereby compartmentalizing protein…

Soft Condensed Matter · Physics 2022-07-27 Danko D. Georgiev , James F. Glazebrook

We investigate some aspects of the soliton dynamics in an alpha-helical protein macromolecule within the steric Davydov-Scott model. Our main objective is to elucidate the important role of the helical symmetry in the formation, stability…

Other Condensed Matter · Physics 2009-11-10 L. Brizhik , A. Eremko , B. Piette , W. Zakrzewski

Following the ideas of Davydov's soliton theory, we study the bio-energy transport in protein molecules. By using a quantum Brownian motion model for a phonon dressed vibrational exciton, we calculate the time-dependence on the mean square…

Biological Physics · Physics 2019-04-01 Theja N. De Silva , Peighton Bolt

We study exciton quantum transfer along a molecular chain whilst accounting for the effects of permanent dipoles that are induced by charge displacements in the molecular orbitals. These effects are typically neglected as they do not arise…

Chemical Physics · Physics 2025-01-14 Adam Burgess , Erik Gauger

The Davydov model of energy transfer in molecular chains is reconsidered assuming the distance dependence of the exciton hopping term. New equations of motion for phonons and excitons are derived within the coherent state approximation.…

Condensed Matter · Physics 2009-10-28 E. A. Bartnik , J. A. Tuszynski , D. Sept

Heuristic insights into a physical picture of Davydov's solitonic model of the one-dimensional protein chain are presented supporting the idea of a non-equilibrium competition between the Davydov phase and a complementary, dynamical-…

Condensed Matter · Physics 2009-10-28 H. C. Rosu

Transport of ions and small molecules across the cell membrane against electrochemical gradients is catalyzed by integral membrane proteins that use a source of free energy to drive the energetically uphill flux of the transported…

Biomolecules · Quantitative Biology 2022-03-25 Oliver Beckstein , Fiona Naughton

Strong coupling between excitons and confined modes of light presents a promising pathway to tunable and enhanced energy transport in organic materials. By forming hybrid light-matter quasiparticles, exciton-polaritons, electronic…

Chemical Physics · Physics 2024-11-01 Niclas Krupp , Gerrit Groenhof , Oriol Vendrell

Currently, molecular tunnel junctions are recognized as important active elements of various nanodevices. This gives a strong motivation to study physical mechanisms controlling electron transport through molecules. Electron motion through…

Mesoscale and Nanoscale Physics · Physics 2013-01-24 Natalya A. Zimbovskaya

Davydov's model of solitons in alpha-helix protein chains is shown to display features of self-organized criticality (SOC), i.e., power law behaviour of correlations in space and 1/f-noise, as a consequence of considering random peptide…

patt-sol · Physics 2008-02-03 H. Rosu , E. Canessa

Davydov's model of solitons in alpha-helix protein chains is shown to display features of self-organized criticality (SOC), i.e., power law behaviour of correlations in space and 1/f-noise, as a consequence of considering random peptide…

Condensed Matter · Physics 2009-10-22 H. Rosu , E. Canessa

We suggest that Davidov's solitons, propagating through the backbone of a protein, can mediate conformational transition and folding of a protein to its native state. A simple toy model is presented in which a Non Linear Schrodinger (NLS)…

Condensed Matter · Physics 2007-05-23 Shay Caspi , Eshel Ben-Jacob

The phenomenon of coherent energetic pulse propagation in exciton-phonon molecular chains such as $\alpha$-helix protein is studied using an ODE system model of Davydov-Scott type, both with numerical studies using a new unconditionally…

Biological Physics · Physics 2015-06-12 Brenton LeMesurier

Cells accomplish diverse functions using the same molecular building blocks, from setting up cytoplasmic flows to generating mechanical forces. In particular, transitions between these non-equilibrium states are triggered by regulating the…

Soft Condensed Matter · Physics 2022-01-03 Bibi Najma , Minu Varghese , Lev Tsidilkovski , Linnea Lemma , Aparna Baskaran , Guillaume Duclos
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