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Achieving greater autonomy in automation systems is crucial for handling unforeseen situations effectively. However, this remains challenging due to technological limitations and the complexity of real-world environments. This paper…

Computational Engineering, Finance, and Science · Computer Science 2025-07-08 Johannes Sigel , Daniel Dittler , Nasser Jazdi , Michael Weyrich

Drug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug…

Artificial Intelligence · Computer Science 2023-07-14 Catrin Hasselgren , Tudor I. Oprea

For decades, computational chemistry has been posited as one of the areas in which quantum computing would revolutionize. However, the algorithmic advantages that fault-tolerant quantum computers have for chemistry can be overwhelmed by…

Autonomous scientific research, capable of independently conducting complex experiments and serving non-specialists, represents a long-held aspiration. Achieving it requires a fundamental paradigm shift driven by artificial intelligence…

Artificial Intelligence · Computer Science 2025-07-04 Mingyu Wu , Zhaoguo Wang , Jiabin Wang , Zhiyuan Dong , Jingkai Yang , Qingting Li , Tianyu Huang , Lei Zhao , Mingqiang Li , Fei Wang , Chunhai Fan , Haibo Chen

In recent years, conventional chemistry techniques have faced significant challenges due to their inherent limitations, struggling to cope with the increasing complexity and volume of data generated in contemporary research endeavors.…

The cognitive sciences aim to understand intelligence by formalizing underlying operations as computational models. Traditionally, this follows a cycle of discovery where researchers develop paradigms, collect data, and test predefined…

Artificial Intelligence · Computer Science 2026-03-24 Akshay K. Jagadish , Milena Rmus , Kristin Witte , Marvin Mathony , Marcel Binz , Eric Schulz

Chemical reaction engineering is key to industrial might and sustainable chemistry. This will be enabled using smart, efficient catalysts or catalysis ecosystems. This is possible with advanced artificial intelligence and machine learning…

Chemical Physics · Physics 2026-03-09 Rigoberto Advincula , Jihua Chen

Large language models (LLMs) are increasingly used in scientific research and discovery, supporting tasks ranging from literature retrieval and synthesis to hypothesis generation, autonomous experimentation, and research evaluation.…

Digital Libraries · Computer Science 2026-05-13 Haoxuan Zhang , Ruochi Li , Yang Zhang , Ting Xiao , Jiangping Chen , Junhua Ding , Haihua Chen

Since its beginnings in the 1940s, automated reasoning by computers has become a tool of ever growing importance in scientific research. So far, the rules underlying automated reasoning have mainly been formulated by humans, in the form of…

Computers and Society · Computer Science 2025-10-20 Konrad Hinsen

The use of automation in digital forensic investigations is not only a technological issue, but also has political and social implications. This work discusses some challenges with the implementation and acceptance of automation in digital…

Computers and Society · Computer Science 2013-03-20 Joshua I. James , Pavel Gladyshev

Fueled by advances in hardware and algorithm design, large-scale automated explorations of chemical reaction space have become possible. Here, we present our approach to an open-source, extensible framework for explorations of chemical…

Chemical Physics · Physics 2022-08-30 Jan P. Unsleber , Stephanie A. Grimmel , Markus Reiher

Natural language processing models have emerged that can generate usable software and automate a number of programming tasks with high fidelity. These tools have yet to have an impact on the chemistry community. Yet, our initial testing…

Statistical Mechanics · Physics 2023-01-11 Glen M. Hocky , Andrew D. White

It has long been known that scientific output proceeds on an exponential increase, or more properly, a logistic growth curve. The interplay between effort and discovery is clear, and the nature of the functional form has been thought to be…

Physics and Society · Physics 2010-05-17 Samuel Arbesman

Machine learning and artificial intelligence (ML/AI) are rapidly becoming an indispensable part of physics research, with domain applications ranging from theory and materials prediction to high-throughput data analysis. In parallel, the…

Robotic Exploration has evolved rapidly in the past two decades as new and more complex techniques have been created to explore unknown regions efficiently. Exciting advancements in exploration, autonomous navigation, and sensor technology…

Robotics · Computer Science 2023-07-18 Akanimoh Adeleye

Process control and optimization have been widely used to solve decision-making problems in chemical engineering applications. However, identifying and tuning the best solution algorithm is challenging and time-consuming. Machine learning…

Systems and Control · Electrical Eng. & Systems 2024-12-25 Ilias Mitrai , Prodromos Daoutidis

This paper studies the impact of artificial intelligence on innovation, exploiting the randomized introduction of a new materials discovery technology to 1,018 scientists in the R&D lab of a large U.S. firm. AI-assisted researchers discover…

General Economics · Economics 2025-05-21 Aidan Toner-Rodgers

The Discovery Engine is a general purpose automated system for scientific discovery, which combines machine learning with state-of-the-art ML interpretability to enable rapid and robust scientific insight across diverse datasets. In this…

The explosive growth of scientific publications has created an urgent need for automated methods that facilitate knowledge synthesis and hypothesis generation. Literature-based discovery (LBD) addresses this challenge by uncovering…

Computation and Language · Computer Science 2025-06-17 Andrej Kastrin , Bojan Cestnik , Nada Lavrač

Automation and semi-automation through computational tools like LLMs are also making their way to deployment in research synthesis and secondary research, such as systematic reviews. In some steps of research synthesis, this has the…

Human-Computer Interaction · Computer Science 2025-01-28 Katja Rogers