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The characterization of interstellar chemical inventories provides valuable insight into the chemical and physical processes in astrophysical sources. The discovery of new interstellar molecules becomes increasingly difficult as the number…

Machine learning is increasingly transforming various scientific fields, enabled by advancements in computational power and access to large data sets from experiments and simulations. As artificial intelligence (AI) continues to grow in…

Computational Physics · Physics 2025-04-01 Sebastian Johann Wetzel , Seungwoong Ha , Raban Iten , Miriam Klopotek , Ziming Liu

Quantum mechanics predicts a number of at first sight counterintuitive phenomena. It is therefore a question whether our intuition is the best way to find new experiments. Here we report the development of the computer algorithm Melvin…

Quantum Physics · Physics 2016-03-07 Mario Krenn , Mehul Malik , Robert Fickler , Radek Lapkiewicz , Anton Zeilinger

We review recent studies dealing with the generation of machine learning models of molecular and solid properties. The models are trained and validated using standard quantum chemistry results obtained for organic molecules and materials…

Chemical Physics · Physics 2016-05-13 Raghunathan Ramakrishnan , O. Anatole von Lilienfeld

The material presented in this paper contributes to establishing a basis deemed essential for substantial progress in Automated Deduction. It identifies and studies global features in selected problems and their proofs which offer the…

Artificial Intelligence · Computer Science 2021-07-14 Christoph Wernhard , Wolfgang Bibel

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos

Robotic Exploration has evolved rapidly in the past two decades as new and more complex techniques have been created to explore unknown regions efficiently. Exciting advancements in exploration, autonomous navigation, and sensor technology…

Robotics · Computer Science 2023-07-18 Akanimoh Adeleye

The continuous increase in the availability of data of any kind, coupled with the development of networks of high-speed communications, the popularization of cloud computing and the growth of data centers and the emergence of…

Artificial Intelligence · Computer Science 2016-09-20 Jose A. García Gutiérrez

Chemistry laboratory automation aims to increase throughput, reproducibility, and safety, yet many existing systems still depend on frequent human intervention. Advances in robotics have reduced this dependency, but without a structured…

Artificial intelligence is reshaping scientific exploration, but most methods automate procedural tasks without engaging in scientific reasoning, limiting autonomy in discovery. We introduce Materials Agents for Simulation and Theory in…

In recent decades the set of knowledge, tools and practices, collectively referred to as "artificial intelligence" (AI), have become a mainstay of scientific research. Artificial intelligence techniques have not only developed enormously…

Physics and Society · Physics 2022-12-26 Floriana Gargiulo , Sylvain Fontaine , Michel Dubois , Paola Tubaro

In this chapter, I review the main methods and techniques of complex systems science. As a first step, I distinguish among the broad patterns which recur across complex systems, the topics complex systems science commonly studies, the tools…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Cosma Rohilla Shalizi

The nexus of quantum computing and machine learning - quantum machine learning - offers the potential for significant advancements in chemistry. This review specifically explores the potential of quantum neural networks on gate-based…

This paper systematically reviews recent advances in artificial intelligence (AI), with a particular focus on machine learning (ML), across the entire drug discovery pipeline. Due to the inherent complexity, escalating costs, prolonged…

Artificial Intelligence · Computer Science 2025-07-08 Junwei Su , Cheng Xin , Ao Shang , Shan Wu , Zhenzhen Xie , Ruogu Xiong , Xiaoyu Xu , Cheng Zhang , Guang Chen , Yau-Tuen Chan , Guoyi Tang , Ning Wang , Yong Xu , Yibin Feng

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

The potential benefits of autonomous systems have been driving intensive development of such systems, and of supporting tools and methodologies. However, there are still major issues to be dealt with before such development becomes…

Software Engineering · Computer Science 2022-05-25 David Harel , Assaf Marron , Joseph Sifakis

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

For the investigation of chemical reaction networks, the identification of all relevant intermediates and elementary reactions is mandatory. Many algorithmic approaches exist that perform explorations efficiently and automatedly. These…

Chemical Physics · Physics 2019-05-24 Gregor N. Simm , Alain C. Vaucher , Markus Reiher

Scientific discovery can be framed as a thermodynamic process in which an agent invests physical work to acquire information about an environment under a finite work budget. Using established results about the thermodynamics of computing,…

Information Theory · Computer Science 2025-11-20 Mihir Rao

Retrosynthesis is the cornerstone of organic chemistry, providing chemists in material and drug manufacturing access to poorly available and brand-new molecules. Conventional rule-based or expert-based computer-aided synthesis has obvious…

Machine Learning · Computer Science 2023-01-18 Zipeng Zhong , Jie Song , Zunlei Feng , Tiantao Liu , Lingxiang Jia , Shaolun Yao , Tingjun Hou , Mingli Song
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