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Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analysis. Improved understanding of these clusters is of utmost importance,…
Feature selection is a crucial step in machine learning, especially for high-dimensional datasets, where irrelevant and redundant features can degrade model performance and increase computational costs. This paper proposes a novel…
Genetic programming is an optimization algorithm inspired by evolution which automatically evolves the structure of interpretable computer programs. The fitness evaluation in genetic programming suffers from high computational requirements,…
Face image retrieval, which searches for images of the same identity from the query input face image, is drawing more attention as the size of the image database increases rapidly. In order to conduct fast and accurate retrieval, a compact…
We propose an unsupervised hashing method which aims to produce binary codes that preserve the ranking induced by a real-valued representation. Such compact hash codes enable the complete elimination of real-valued feature storage and allow…
\textit{Drosophila melanogaster} has been established as a model organism for investigating the fundamental principles of developmental gene interactions. The gene expression patterns of \textit{Drosophila melanogaster} can be documented as…
Fast similarity search is a key component in large-scale information retrieval, where semantic hashing has become a popular strategy for representing documents as binary hash codes. Recent advances in this area have been obtained through…
Materialized views can significantly improve database query performance but identifying the optimal set of views to materialize is challenging. Prior work on automating and optimizing materialized view selection has limitations in execution…
Non-dominated Sorting Genetic Algorithm (NSGA) has established itself as a benchmark algorithm for Multiobjective Optimization. The determination of pareto-optimal solutions is the key to its success. However the basic algorithm suffers…
In early-stage architectural design, optimization algorithms are essential for efficiently exploring large and complex design spaces under tight computational constraints. While prior research has benchmarked various optimization methods,…
In this paper, we introduce a novel method for merging the weights of multiple pre-trained neural networks using a genetic algorithm called MeGA. Traditional techniques, such as weight averaging and ensemble methods, often fail to fully…
Geometric Semantic Genetic Programming (GSGP) is a state-of-the-art machine learning method based on evolutionary computation. GSGP performs search operations directly at the level of program semantics, which can be done more efficiently…
Evolving one-dimensional cellular automata (CAs) with genetic algorithms has provided insight into how improved performance on a task requiring global coordination emerges when only local interactions are possible. Two approaches that can…
Benchmarking the performance of information retrieval (IR) is mostly conducted with a fixed set of documents (static corpora). However, in realistic scenarios, this is rarely the case and the documents to be retrieved are constantly updated…
We describe a regularized regression model for the selection of gene-environment (GxE) interactions. The model focuses on a single environmental exposure and induces a main-effect-before-interaction hierarchical structure. We propose an…
Most evolutionary algorithms (EAs) used in practice employ crossover. In contrast, only for few and mostly artificial examples a runtime advantage from crossover could be proven with mathematical means. The most convincing such result shows…
Survival prediction is an important branch of cancer prognosis analysis. The model that predicts survival risk through TCGA genomics data can discover genes related to cancer and provide diagnosis and treatment recommendations based on…
We present GenEx, a generative model to explain search results to users beyond just showing matches between query and document words. Adding GenEx explanations to search results greatly impacts user satisfaction and search performance.…
Efficient text indexing data structures have enabled large-scale genomic sequence analysis and are used to help solve problems ranging from assembly to read mapping. However, these data structures typically assume that the underlying…
As the core technique of online recruitment platforms, person-job fit can improve hiring efficiency by accurately matching job positions with qualified candidates. However, existing studies mainly focus on the recommendation scenario, while…