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The manner in which electrolyte solutions respond to electric fields is crucial to understanding the behavior of these systems both at, and away from, equilibrium. The present formulation of linear response theory for such systems is…

Statistical Mechanics · Physics 2020-05-21 Stephen J. Cox , Michiel Sprik

Understanding the response of the surface of metallic solids to external electric field sources is crucial to characterize electrode-electrolyte interfaces. Continuum electrostatics offer a simple description of the induced charge density…

Chemical Physics · Physics 2021-12-14 Giovanni Pireddu , Laura Scalfi , Benjamin Rotenberg

In computational molecular science, calculation of electrostatic interactions involving charged atoms - the strongest interactions in condensed phases, is a major bottleneck. We propose a quantum-classical algorithm for fast, yet, accurate…

Quantum Physics · Physics 2026-02-18 Mansur Ziiatdinov , Igor Novikov , Farid Ablayev , Valeri Barsegov

We describe a self-contained procedure to evaluate the free energy of liquid and solid phases of an alloy system. The free energy of a single-element solid phase is calculated with thermodynamic integration using the Einstein crystal as the…

Statistical Mechanics · Physics 2021-02-05 Lin Yang , Yang Sun , Zhuo Ye , Feng Zhang , Mikhail I. Mendelev , Cai-Zhuang Wang , Kai-Ming Ho

Tasker type III polar terminations of ionic crystals carry a net surface charge as well as a dipole moment and are fundamentally unstable. In contact with electrolytes, such polar surfaces can be stabilized by adsorption of counter ions…

Chemical Physics · Physics 2019-03-22 Thomas Sayer , Michiel Sprik , Chao Zhang

To minimise systematic errors in Monte Carlo simulations of charged particles, long range electrostatic interactions have to be calculated accurately and efficiently. Standard approaches, such as Ewald summation or the naive application of…

Computational Physics · Physics 2021-02-24 William Robert Saunders , James Grant , Eike Hermann Müller

Accurate predictions of charge excitation energies of molecules in the disordered condensed phase are central to the chemical reactivity, stability, and optoelectronic properties of molecules and critically depend on the specific…

Chemical Physics · Physics 2021-08-25 Guorong Weng , Vojtech Vlcek

In recent years, molecular dynamics (MD) simulations have emerged as a pivotal tool for understanding the structure, dynamics, and phase behavior in charged soft matter systems. To explore phenomena across greater length and time scales in…

Computational Physics · Physics 2024-07-18 Benjamin Bobin Ye , Shensheng Chen , Zhen-Gang Wang

The solvation free energy (SFE) of molecules and ions is a fundamental property governing their solvation behavior and solubility. Molecular simulations offer a route to compute SFEs using alchemical free energy methods, such as…

Chemical Physics · Physics 2026-04-21 Junting Yu , Shuo-Hui Li , Ding Pan

We present a computational study of static and dynamic linear polarizabilities in solution. We use different theoretical approaches to describe solvent effects, ranging from quantum mechanics/molecular mechanics (QM/MM) to quantum embedding…

Chemical Physics · Physics 2022-12-07 Linda Goletto , Sara Gómez , Josefine H. Andersen , Henrik Koch , Tommaso Giovannini

We propose and justify a new approach for fast calculation of the electrostatic interaction energy of clusters of charged particles in constrained energy minimization in the framework of rigid protein-ligand docking. Our ``blind search''…

Numerical Analysis · Mathematics 2025-10-31 Peter Benner , Boris N. Khoromskij , Venera Khoromskaia , Matthias Stein

Free energies govern the behavior of soft and liquid matter, and improving their predictions could have a large impact on the development of drugs, electrolytes or homogeneous catalysts. Unfortunately, it is challenging to devise an…

Chemical Physics · Physics 2021-04-14 Jan Weinreich , Nicholas J. Browning , O. Anatole von Lilienfeld

We present an efficient \textit{ab initio} method for calculating the electronic structure and total energy of strongly correlated electron systems. The method extends the traditional Gutzwiller approximation for one-particle operators to…

Strongly Correlated Electrons · Physics 2014-07-01 Y. X. Yao , J. Liu , C. Liu , W. C. Lu , C. Z. Wang , K. M. Ho

In this paper, a fast multipole method (FMM) is proposed for 3-D Laplace equation in layered media. The potential due to charges embedded in layered media is decomposed into a free space component and four types of reaction field…

Numerical Analysis · Mathematics 2020-05-26 Bo Wang , Wen Zhong Zhang , Wei Cai

Computational studies of electrochemical interfaces based on density-functional theory (DFT) play an increasingly important role in present research on electrochemical processes for energy conversion and storage. The homogeneous background…

Materials Science · Physics 2022-04-26 Arthur Hagopian , Marie-Liesse Doublet , Jean-Sébastien Filhol , Tobias Binninger

We present an approximate method for calculating the electrostatic free energy of concentrated protein solutions. Our method uses a cell model and accounts for both the coulomb energy and the entropic cost of Donnan salt partitioning. The…

Biological Physics · Physics 2013-04-10 Shradha Mishra , Jeremy D. Schmit

A major challenge in the molecular simulation of electric double layer capacitors (EDLCs) is the choice of an appropriate model for the electrode. Typically, in such simulations the electrode surface is modeled using a uniform fixed charge…

Computational Physics · Physics 2015-06-22 Zhenxing Wang , Yang Yang , David L. Olmsted , Mark Asta , Brian B. Laird

We present an efficient algorithm for computing the exact exchange contributions in the Hartree-Fock and hybrid density functional theory models on the basis of the fast multipole method (FMM). Our algorithm is based on the observation that…

Chemical Physics · Physics 2018-01-30 Hai-Anh Le , Toru Shiozaki

Hypotheses: To correctly predict the aggregation number and size of wormlike micelles from ionic surfactants, the molecular-thermodynamic theory has to calculate the free energy per molecule in the micelle with accuracy better than 0.01 kT,…

Soft Condensed Matter · Physics 2020-07-28 K. D. Danov , P. A. Kralchevsky , S. D. Stoyanov , J. L. Cook , I. P. Stott

Optimal exploitation of supercomputing resources for the evaluation of electrostatic forces remains a challenge in molecular dynamics simulations of very large systems. The most efficient methods are currently based on particle-mesh Ewald…

Computational Physics · Physics 2025-09-23 Federica Troni , Davide Grassano , Jayashree Narayan , Benoît Roux , Sara Bonella