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This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of…

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

Data assimilation refers to the problem of finding trajectories of a prescribed dynamical model in such a way that the output of the model (usually some function of the model states) follows a given time series of observations. Typically…

Atmospheric and Oceanic Physics · Physics 2015-05-30 Jochen Bröcker , Ivan G. Szendro

Rule-based models have been successfully used to represent different aspects of the COVID-19 pandemic, including age, testing, hospitalisation, lockdowns, immunity, infectivity, behaviour, mobility and vaccination of individuals. These…

Populations and Evolution · Quantitative Biology 2022-10-25 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

The long duration of the COVID-19 pandemic allowed for multiple bursts in the infection and death rates, the so-called epidemic waves. This complex behavior is no longer tractable by simple compartmental model and requires more…

Spatio-temporal models for infection counts generally follow themes of the broader disease mapping literature, but may need to address specific features of spatio-temporal infection data including considerable time fluctuations (with…

Applications · Statistics 2022-02-22 P. Congdon

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

We analyze an epidemic model on a network consisting of susceptible-infected-recovered equations at the nodes coupled by diffusion using a graph Laplacian. We introduce an epidemic criterion and examine different vaccination/containment…

Physics and Society · Physics 2020-09-25 F. Bustamante-Castaneda , J. -G. Caputo , G. Cruz-Pacheco , A. Knippel , F. Mouatamide

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…

Populations and Evolution · Quantitative Biology 2024-09-09 Ning Jiang , Weiqi Chu , Yao Li

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

Methodology · Statistics 2023-06-26 Chih-Li Sung , Ying Hung

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

Methodology · Statistics 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

We study the reported data from the COVID-19 pandemic outbreak in January - May 2020 in 119 countries. We observe that the time series of active cases in individual countries (the difference of the total number of confirmed infections and…

Populations and Evolution · Quantitative Biology 2020-05-15 Katarina Bodova , Richard Kollar

A finite mixture model is used to learn trends from the currently available data on coronavirus (COVID-19). Data on the number of confirmed COVID-19 related cases and deaths for European countries and the United States (US) are explored. A…

Applications · Statistics 2021-09-16 Semhar Michael , Xuwen Zhu , Volodymyr Melnykov

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

Variational data assimilation optimizes for an initial state of a dynamical system such that its evolution fits observational data. The physical model can subsequently be evolved into the future to make predictions. This principle is a…

Machine Learning · Computer Science 2021-05-21 Thomas Frerix , Dmitrii Kochkov , Jamie A. Smith , Daniel Cremers , Michael P. Brenner , Stephan Hoyer

Data scarcity and discontinuity are common occurrences in the healthcare and epidemiological dataset and often need help in forming an educative decision and forecasting the upcoming scenario. Often, these data are stored as monthly/yearly…

Other Statistics · Statistics 2023-04-25 Mahadee Al Mobin , Md. Kamrujjaman

We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number $I(t)$ of infectious individuals at time $t$ in classical SIR models and their derivatives. We present a novel method for…

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