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Deep reinforcement learning is an emerging machine learning approach which can teach a computer to learn from their actions and rewards similar to the way humans learn from experience. It offers many advantages in automating decision…

Mesoscale and Nanoscale Physics · Physics 2021-07-08 V. Nguyen , S. B. Orbell , D. T. Lennon , H. Moon , F. Vigneau , L. C. Camenzind , L. Yu , D. M. Zumbühl , G. A. D. Briggs , M. A. Osborne , D. Sejdinovic , N. Ares

Skilled robot task learning is best implemented by predictive action policies due to the inherent latency of sensorimotor processes. However, training such predictive policies is challenging as it involves finding a trajectory of motor…

Robotics · Computer Science 2017-03-03 Ali Ghadirzadeh , Atsuto Maki , Danica Kragic , Mårten Björkman

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

We consider the problem of learning an optimal prescriptive tree (i.e., an interpretable treatment assignment policy in the form of a binary tree) of moderate depth, from observational data. This problem arises in numerous socially…

Machine Learning · Computer Science 2023-07-25 Nathanael Jo , Sina Aghaei , Andrés Gómez , Phebe Vayanos

In the fight against hard-to-treat diseases such as cancer, it is often difficult to discover new treatments that benefit all subjects. For regulatory agency approval, it is more practical to identify subgroups of subjects for whom the…

Methodology · Statistics 2014-10-09 Wei-Yin Loh , Xu He , Michael Man

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Purpose: Image classification may be the fundamental task in imaging artificial intelligence. We have recently shown that reinforcement learning can achieve high accuracy for lesion localization and segmentation even with minuscule training…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu

A key task in Artificial Intelligence is learning effective policies for controlling agents in unknown environments to optimize performance measures. Off-policy learning methods, like Q-learning, allow learners to make optimal decisions…

Artificial Intelligence · Computer Science 2025-10-27 Mingxuan Li , Junzhe Zhang , Elias Bareinboim

Efficient representation of patients is very important in the healthcare domain and can help with many tasks such as medical risk prediction. Many existing methods, such as diagnostic Cost Groups (DCG), rely on expert knowledge to build…

Machine Learning · Computer Science 2019-09-17 Xianlong Zeng , Soheil Moosavinasab , En-Ju D Lin , Simon Lin , Razvan Bunescu , Chang Liu

This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state…

Artificial Intelligence · Computer Science 2018-01-30 Ning Liu , Ying Liu , Brent Logan , Zhiyuan Xu , Jian Tang , Yanzhi Wang

An effective way to achieve intelligence is to simulate various intelligent behaviors in the human brain. In recent years, bio-inspired learning methods have emerged, and they are different from the classical mathematical programming…

Artificial Intelligence · Computer Science 2019-04-01 Jieneng Chen , Jingye Chen , Ruiming Zhang , Xiaobin Hu

Precision medicine aims to tailor therapeutic decisions to individual patient characteristics. This objective is commonly formalized through dynamic treatment regimes, which use statistical and machine learning methods to derive sequential…

Machine Learning · Statistics 2026-03-23 Sophia Yazzourh , Erica E. M. Moodie

The goal of precision medicine is to provide individualized treatment at each stage of chronic diseases, a concept formalized by Dynamic Treatment Regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from…

Methodology · Statistics 2025-06-09 Sophia Yazzourh , Nicolas Savy , Philippe Saint-Pierre , Michael R. Kosorok

Reinforcement learning has received high research interest for developing planning approaches in automated driving. Most prior works consider the end-to-end planning task that yields direct control commands and rarely deploy their algorithm…

Robotics · Computer Science 2023-07-31 Marvin Klimke , Benjamin Völz , Michael Buchholz

Massive electronic health records (EHRs) enable the success of learning accurate patient representations to support various predictive health applications. In contrast, doctor representation was not well studied despite that doctors play…

Machine Learning · Computer Science 2019-11-26 Siddharth Biswal , Cao Xiao , Lucas M. Glass , Elizabeth Milkovits , Jimeng Sun

Experts advising decision-makers are likely to display expertise which varies as a function of the problem instance. In practice, this may lead to sub-optimal or discriminatory decisions against minority cases. In this work we model such…

Artificial Intelligence · Computer Science 2023-10-27 Axel Abels , Tom Lenaerts , Vito Trianni , Ann Nowé

Clinical trials (CTs) often fail due to inadequate patient recruitment. This paper tackles the challenges of CT retrieval by presenting an approach that addresses the patient-to-trials paradigm. Our approach involves two key components in a…

Information Retrieval · Computer Science 2023-07-04 Wojciech Kusa , Óscar E. Mendoza , Petr Knoth , Gabriella Pasi , Allan Hanbury

High performance packet classification is a key component to support scalable network applications like firewalls, intrusion detection, and differentiated services. With ever increasing in the line-rate in core networks, it becomes a great…

Networking and Internet Architecture · Computer Science 2022-05-19 Hasibul Jamil , Ning Weng

We develop methodology for a multistage decision problem with flexible number of stages in which the rewards are survival times that are subject to censoring. We present a novel Q-learning algorithm that is adjusted for censored data and…

Statistics Theory · Mathematics 2012-05-31 Yair Goldberg , Michael R. Kosorok

In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming…

Computers and Society · Computer Science 2020-06-25 Lichin Chen , Yu Tsao , Ji-Tian Sheu