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Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Jaejun Yoo , Sohail Sabir , Duchang Heo , Kee Hyun Kim , Abdul Wahab , Yoonseok Choi , Seul-I Lee , Eun Young Chae , Hak Hee Kim , Young Min Bae , Young-wook Choi , Seungryong Cho , Jong Chul Ye

Medical imaging is nowadays a pillar in diagnostics and therapeutic follow-up. Current research tries to integrate established - but ionizing - tomographic techniques with technologies offering reduced radiation exposure. Diffuse Optical…

Numerical Analysis · Mathematics 2024-02-15 Alessandro Benfenati , Paola Causin , Martina Quinteri

Diffuse optical tomography (DOT) utilises near-infrared light for imaging spatially distributed optical parameters, typically the absorption and scattering coefficients. The image reconstruction problem of DOT is an ill-posed inverse…

Computational Physics · Physics 2021-12-15 Meghdoot Mozumder , Andreas Hauptmann , Ilkka Nissilä , Simon R. Arridge , Tanja Tarvainen

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

Medical Physics · Physics 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…

Numerical Analysis · Mathematics 2022-05-27 Alessandro Benfenati , Giuseppe Bisazza , Paola Causin

A two-step shape reconstruction method for diffuse optical tomography (DOT) is presented which uses adjoint fields and level sets. The propagation of near-infrared photons in tissue is modeled by the time-dependent linear transport…

Numerical Analysis · Mathematics 2025-10-20 Oliver Dorn

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

Light scattering imposes a major obstacle for imaging objects seated deeply in turbid media, such as biological tissues and foggy air. Diffuse optical tomography (DOT) tackles scattering by volumetrically recovering the optical absorbance…

Limited-Angle Computed Tomography (LACT) is a challenging inverse problem where missing angular projections lead to incomplete sinograms and severe artifacts in the reconstructed images. While recent learning-based methods have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Jiaqi Guo , Santiago López-Tapia

Diffuse optical tomography (DOT) is an imaging modality which uses near-infrared light. Although iterative numerical schemes are commonly used for its inverse problem, correct solutions are not obtained unless good initial guesses are…

Numerical Analysis · Mathematics 2021-06-07 Yu Jiang , Manabu Machida , Norikazu Todoroki

Limited-Angle Computed Tomography (LACT) is a non-destructive evaluation technique used in a variety of applications ranging from security to medicine. The limited angle coverage in LACT is often a dominant source of severe artifacts in the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Jiaming Liu , Rushil Anirudh , Jayaraman J. Thiagarajan , Stewart He , K. Aditya Mohan , Ulugbek S. Kamilov , Hyojin Kim

This paper deals with the problem of building fast and reliable 3D reconstruction methods for blood flows for which partial information is given by Doppler ultrasound measurements. This task is of interest in medicine since it could enrich…

Numerical Analysis · Mathematics 2020-11-05 Felipe Galarce , Jean-Frédéric Gerbeau , Damiano Lombardi , Olga Mula

The image reconstruction of chromophore concentrations using Diffuse Optical Tomography (DOT) data can be described mathematically as an ill-posed inverse problem. Recent work has shown that the use of hyperspectral DOT data, as opposed to…

Numerical Analysis · Mathematics 2014-10-16 Arvind K. Saibaba , Misha Kilmer , Eric Miller , Sergio Fantini

In this paper, we present a novel reconstruction method for diffuse optical spectroscopic imaging with a commonly used tissue model of optical absorption and scattering. It is based on linearization and group sparsity, which allows…

Numerical Analysis · Mathematics 2019-03-06 Habib Ammari , Bangti Jin , Wenlong Zhang

Purpose: To develop an algorithm for robust partial Fourier (PF) reconstruction applicable to diffusion-weighted (DW) images with non-smooth phase variations. Methods: Based on an unrolled proximal splitting algorithm, a neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Fasil Gadjimuradov , Thomas Benkert , Marcel Dominik Nickel , Andreas Maier

When the inverse problem of diffuse optical tomography (DOT) is solved with the Born or Rytov approximation, the size of the matrix of the linear inverse problem becomes large if the volume (or area) of the domain in biological tissue used…

Medical Physics · Physics 2021-07-22 Tetsuya Mimura , Yu Jiang , Norikazu Todoroki , Manabu Machida

In this work, we investigate the diffusive optical tomography (DOT) problem in the case that limited boundary measurements are available. Motivated by the direct sampling method (DSM), we develop a deep direct sampling method (DDSM) to…

Numerical Analysis · Mathematics 2021-05-10 Jiahua Jiang , Yi Li , Ruchi Guo

Limited Angle Computed Tomography (LACT) often faces significant challenges due to missing angular information. Unlike previous methods that operate in the image domain, we propose a new method that focuses on sinogram inpainting. We…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Jiaqi Guo , Santiago Lopez-Tapia , Aggelos K. Katsaggelos

Nonlinear parametric inverse problems appear in many applications. Here, we focus on diffuse optical tomography (DOT) in medical imaging to recover unknown images of interest, such as cancerous tissue in a given medium, using a mathematical…

Numerical Analysis · Mathematics 2020-07-14 Selin Aslan , Eric de Sturler , Serkan Gugercin

Optical coherence Doppler tomography (ODT) is an emerging blood flow imaging technique. The fundamental unit of ODT is the 1D depth-resolved trace named raw A-scans (or A-line). A 2D ODT image (B-scan) is formed by reconstructing a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Zhenghong Li , Jiaxiang Ren , Wensheng Cheng , Yanzuo Liu , Congwu Du , Yingtian Pan , Haibin Ling
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