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This article examines the effect of individual and combined uncertainties in thermodynamic models on the performance of simulated, steady-state Pareto-optimized Dividing Wall Columns. It is a follow-up of the previous work analogously…

Chemical Physics · Physics 2025-05-22 Lea Trescher , David Mogalle , Patrick Otto Ludl , Tobias Seidel , Michael Bortz , Thomas Gruetzner

An important characteristic that determines the behavior of a solute in water is whether it is hydrophobic or hydrophilic. The traditional classification is based on chemical experience and heuristics. However, this does not reveal how the…

Chemical Physics · Physics 2019-06-26 S. Pérez-Conesa , Pablo M. Piaggi , Michele Parrinello

Modern theories of the hydrophobic effect highlight its dependence on length scale, emphasizing in particular the importance of interfaces that emerge in the vicinity of sizable hydrophobes. We recently showed that a faithful treatment of…

Statistical Mechanics · Physics 2016-06-06 Suriyanarayanan Vaikuntanathan , Grant M Rotskoff , Alexander Hudson , Phillip Geissler

We derive the Hydrodynamics for a system of N active, spherical, underdamped particles, interacting through conservative forces. At the microscopic level, we represent the evolution of the particles in terms of the Kramers equation for the…

Statistical Mechanics · Physics 2022-03-15 Umberto Marini Bettolo Marconi , Andrea Puglisi , Lorenzo Caprini

The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane. However, we currently do not have the methods to quantify the…

Biological Physics · Physics 2023-06-21 Daniel P. Arnold , Yaxin Xu , Sho C. Takatori

The thermodynamic properties for three different types of off-lattice four-strand beta-sheet protein models interacting via a hybrid Go-type potential have been investigated. Discontinuous molecular dynamic simulations have been performed…

Biological Physics · Physics 2009-11-07 Hyunbum Jang , Carol K. Hall , Yaoqi Zhou

In developing organisms, internal cellular processes generate mechanical stresses at the tissue scale. The resulting deformations depend on the material properties of the tissue, which can exhibit long-ranged orientational order and…

Soft Condensed Matter · Physics 2021-01-20 Carles Blanch-Mercader , Pau Guillamat , Aurélien Roux , Karsten Kruse

Concentrated solutions of monoclonal antibodies have attracted considerable attention due to their importance in pharmaceutical formulations, yet their tendency to aggregate and the resulting high solution viscosity has posed considerable…

We present a graph theory-based method to characterise flow defects and structural shifts in condensed matter. We explore the connection between dynamical properties, particularly the recently introduced concept of ''softness'', and…

Disordered Systems and Neural Networks · Physics 2024-08-13 An Wang , Gabriele C. Sosso

Protein structure prediction based on Hydrophobic-Polar energy model essentially becomes searching for a conformation having a compact hydrophobic core at the center. The hydrophobic core minimizes the interaction energy between the amino…

Computational Engineering, Finance, and Science · Computer Science 2013-11-01 Swakkhar Shatabda , M. A. Hakim Newton , Duc Nghia Pham , Abdul Sattar

In order to better understand the occurrence of phase transitions, we adopt an approach based on the study of energy landscapes: The relation between stationary points of the potential energy landscape of a classical many-particle system…

Statistical Mechanics · Physics 2009-03-24 Michael Kastner

The impact of a jet of droplets upon surfaces of varying hydrophobicity is studied via high-speed imaging. Microstructures on silicone surfaces consisting of cylindrical pillars of varying sizes and spacings are utilized to enhance…

A domain wall separating two different topological phases of the same crystal can support the propagation of backscattering-immune guided waves. In valley-Hall and quantum-Hall crystal waveguides, this property stems from symmetry…

Classical Physics · Physics 2023-06-30 Julio Andrés Iglesias Martínez , Nicolas Laforge , Muamer Kadic , Vincent Laude

Smoothed Particle Hydrodynamics (SPH) methods are advantageous in simulations of fluids in domains with free boundary. Special SPH methods have also been developed to simulate solids. However, there are situations where the matter behaves…

Fluid Dynamics · Physics 2024-01-18 Ondřej Kincl , Ilya Peshkov , Michal Pavelka , Václav Klika

The aim of this work is to elucidate how physical principles of protein design are reflected in natural sequences that evolved in response to the thermal conditions of the environment. Using an exactly solvable lattice model, we design…

Biomolecules · Quantitative Biology 2015-06-26 Igor N. Berezovsky , Konstantin B. Zeldovich , Eugene I. Shakhnovich

A high level polarizable force field is used to study the temperature dependence of hydrophobic hydration of small-sized molecules from computer simulations. Molecular dynamics (MD) simulations of liquid water at various temperatures form…

Biological Physics · Physics 2007-11-27 R. Mahajan , D. Krazmueller , U. H. E. Hansmann , J. Volkert , S. Hoefinger

The relation between thermodynamic phase transitions in classical systems and topology changes in their state space is discussed for systems in which equivalence of statistical ensembles does not hold. As an example, the spherical model…

Statistical Mechanics · Physics 2007-05-23 Michael Kastner

Using molecular dynamics simulations we study the thermodynamic behavior of a single-component covalent material described by the recently proposed Environment-Dependent Interatomic Potential (EDIP). The parameterization of EDIP for silicon…

Materials Science · Physics 2009-11-07 P. Keblinski , M. Z. Bazant , R. K. Dash , M. M. Treacy

A series of laboratory experiments has been carried out in a thermally driven rotating annulus to study the onset of baroclinic instability, using horizontal and uniformly sloping bottom topographies. Different wave flow regimes have been…

Fluid Dynamics · Physics 2015-06-17 Miklos Vincze , Uwe Harlander , Thomas von Larcher , Christoph Egbers

The spatial arrangement of components within an mRNA encapsulating nanoparticle has consequences for its thermal stability, which is a key parameter for therapeutic utility. The mesostructure of mRNA nanoparticles formed with cationic…

Soft Condensed Matter · Physics 2024-10-02 Emmit K. Pert , Paul J. Hurst , Robert M. Waymouth , Grant M. Rotskoff
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