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One of the central goals in precision health is the understanding and interpretation of high-dimensional biological data to identify genes and markers associated with disease initiation, development, and outcomes. Though significant effort…

Quantitative Methods · Quantitative Biology 2020-09-18 Zhi Huang , Paul Salama , Wei Shao , Jie Zhang , Kun Huang

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

This paper presents a method based on a kernel dictionary learning algorithm for segmenting brain tumor regions in magnetic resonance images (MRI). A set of first-order and second-order statistical feature vectors are extracted from patches…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Seyedeh Mahya Mousavi , Mohammad Mostafavi

Digital image segmentation is the process of assigning distinct labels to different objects in a digital image, and the fuzzy segmentation algorithm has been successfully used in the segmentation of images from a wide variety of sources.…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 José F. S. Neto , Waldson P. N. Leandro , Matheus A. Gadelha , Tiago S. Santos , Bruno M. Carvalho , Edgar Garduño

Feature selection is an essential process in machine learning, especially when dealing with high-dimensional datasets. It helps reduce the complexity of machine learning models, improve performance, mitigate overfitting, and decrease…

Machine Learning · Computer Science 2024-10-10 Egor Kraev , Baran Koseoglu , Luca Traverso , Mohammed Topiwalla

This paper proposes a novel fuzzy action selection method to leverage human knowledge in reinforcement learning problems. Based on the estimates of the most current action-state values, the proposed fuzzy nonlinear mapping as-signs each…

Artificial Intelligence · Computer Science 2021-06-15 Mohsen Annabestani , Ali Abedi , Mohammad Reza Nematollahi , Mohammad Bagher Naghibi Sis-tani

Deep clustering outperforms conventional clustering by mutually promoting representation learning and cluster assignment. However, most existing deep clustering methods suffer from two major drawbacks. First, most cluster assignment methods…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Hanxuan Wang , Na Lu , Qinyang Liu

Simultaneous feature selection and non-linear function estimation is challenging in modeling, especially in high-dimensional settings where the number of variables exceeds the available sample size. In this article, we investigate the…

Machine Learning · Statistics 2026-01-05 Bin Luo , Susan Halabi

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Fingerprint classification is an effective technique for reducing the candidate numbers of fingerprints in the stage of matching in automatic fingerprint identification system (AFIS). In recent years, deep learning is an emerging technology…

Computer Vision and Pattern Recognition · Computer Science 2014-09-19 Ruxin Wang , Congying Han , Yanping Wu , Tiande Guo

Accurately identifying cancer samples is crucial for precise diagnosis and effective patient treatment. Traditional methods falter with high-dimensional and high feature-to-sample count ratios, which are critical for classifying cancer…

Machine Learning · Computer Science 2025-01-14 Tareque Mohmud Chowdhury , Farzana Tabassum , Sabrina Islam , Abu Raihan Mostofa Kamal

The need to measure bias encoded in tabular data that are used to solve pattern recognition problems is widely recognized by academia, legislators and enterprises alike. In previous work, we proposed a bias quantification measure, called…

Machine Learning · Computer Science 2022-01-24 Gonzalo Nápoles , Lisa Koutsoviti Koumeri

Fuzzy systems concern fundamental methodology to represent and process uncertainty and imprecision in the linguistic information. The fuzzy systems that use fuzzy rules to represent the domain knowledge of the problem are known as Fuzzy…

Computer Vision and Pattern Recognition · Computer Science 2012-06-21 Koushik Mondal , Paramartha Dutta , Siddhartha Bhattacharyya

Popular approaches for few-shot classification consist of first learning a generic data representation based on a large annotated dataset, before adapting the representation to new classes given only a few labeled samples. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Nikita Dvornik , Cordelia Schmid , Julien Mairal

Evolutionary computation methods have been successfully applied to neural networks since two decades ago, while those methods cannot scale well to the modern deep neural networks due to the complicated architectures and large quantities of…

Neural and Evolutionary Computing · Computer Science 2019-03-12 Yanan Sun , Bing Xue , Mengjie Zhang , Gary G. Yen

Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

DNA methylation is a well-studied genetic modification that regulates gene transcription of Eukaryotes. Its alternations have been recognized as a significant component of cancer development. In this study, we use the DNA methylation 450k…

Tissues and Organs · Quantitative Biology 2021-01-05 Shen Jia , Yulin Zhang , Yiming Mao , Jiawei Gao , Yixuan Chen , Yuxuan Jiang , Haochen Luo , Kebo Lv , Jionglong Su

In this paper, we generalize image (texture) statistical descriptors and propose algorithms that improve their efficacy. Recently, a new method showed how the popular Co-Occurrence Matrix (COM) can be modified into a fuzzy version (FCOM)…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Guillaume Thibault , Izhak Shafran

Genetic algorithms are a widely used method in chemometrics for extracting variable subsets with high prediction power. Most fitness measures used by these genetic algorithms are based on the ordinary least-squares fit of the resulting…

Computation · Statistics 2017-11-21 David Kepplinger , Peter Filzmoser , Kurt Varmuza

Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck that…

Quantitative Methods · Quantitative Biology 2020-07-20 Parth Patel , Kalpdrum Passi , Chakresh Kumar Jain
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