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Widespread adoption of AI for medical decision making is still hindered due to ethical and safety-related concerns. For AI-based decision support systems in healthcare settings it is paramount to be reliable and trustworthy. Common deep…

Machine Learning · Computer Science 2024-01-26 Adrian Lindenmeyer , Malte Blattmann , Stefan Franke , Thomas Neumuth , Daniel Schneider

This investigation examines the efficacy of multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) over fixed effect models when performing intersectional studies. The research questions are: 1) What are…

Physics Education · Physics 2024-03-20 Ben Van Dusen , Heidi Cian , Jayson Nissen , Lucy Arellano , Adrienne Woods

For many scientific questions, understanding the underlying mechanism is the goal. To help investigators better understand the underlying mechanism, variable selection is a crucial step that permits the identification of the most associated…

Methodology · Statistics 2025-10-06 Shuangshuang Xu , Marco A. R. Ferreira , Allison N. Tegge

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

this article illustrates the use of linear and bilinear random effects models to represent statistical dependencies that often characterize dyadic data such as international relations. In particular, we show how to estimate models for…

Applications · Statistics 2008-01-14 S. Alimoradi , M. Khalilian

We consider the problem of state estimation from limited discrete and noisy measurements. In particular, we focus on modal state estimation, which approximates the unknown state of the system within a prescribed basis. We estimate the…

Numerical Analysis · Mathematics 2025-05-08 Lev Kakasenko , Alen Alexanderian , Mohammad Farazmand , Arvind K. Saibaba

This chapter presents an overview of a specific form of limited dependent variable models, namely discrete choice models, where the dependent (response or outcome) variable takes values which are discrete, inherently ordered, and…

Econometrics · Economics 2023-05-30 Mohit Batham , Soudeh Mirghasemi , Mohammad Arshad Rahman , Manini Ojha

With the advent of generative modeling techniques, synthetic data and its use has penetrated across various domains from unstructured data such as image, text to structured dataset modeling healthcare outcome, risk decisioning in financial…

Machine Learning · Computer Science 2021-05-11 Aman Gupta , Deepak Bhatt , Anubha Pandey

Digital twins have been actively explored in many engineering applications, such as manufacturing and autonomous systems. However, model discrepancy is ubiquitous in most digital twin models and has significant impacts on the performance of…

Machine Learning · Computer Science 2025-08-12 Huchen Yang , Chuanqi Chen , Jin-Long Wu

Offline Behavior Distillation (OBD), which condenses massive offline RL data into a compact synthetic behavioral dataset, offers a promising approach for efficient policy training and can be applied across various downstream RL tasks. In…

Machine Learning · Computer Science 2025-12-09 Shiye Lei , Zhihao Cheng , Dacheng Tao

In many scientific and engineering domains, physical experiments are often costly, non-replicable, or time-consuming. The Kennedy and O'Hagan (KOH) model framework has become a widely used approach for combining simulator runs with limited…

Computation · Statistics 2026-03-18 Hao Zhu , Markus Hainy

Large sample behavior of dynamic information borrowing (DIB) estimators is investigated. Asymptotic properties of several DIB approaches (adaptive risk minimization, adaptive LASSO, Bayesian procedures with empirical power prior, fully…

Methodology · Statistics 2025-03-03 Sergey Tarima , Silvia Calderazzo , Mary Homan

The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…

Methodology · Statistics 2026-01-07 Richik Chakraborty

The renowned difference-in-differences (DiD) estimator relies on the assumption of 'parallel trends,' which does not hold in many practical applications. To address this issue, the econometrics literature has turned to the triple difference…

Methodology · Statistics 2024-02-21 Sina Akbari , Negar Kiyavash

Cognitive processes undergo various fluctuations and transient states across different temporal scales. Superstatistics are emerging as a flexible framework for incorporating such non-stationary dynamics into existing cognitive model…

Neurons and Cognition · Quantitative Biology 2024-10-02 Lukas Schumacher , Martin Schnuerch , Andreas Voss , Stefan T. Radev

Clinical trials often evaluate multiple outcome variables to form a comprehensive picture of the effects of a new treatment. The resulting multidimensional insight contributes to clinically relevant and efficient decision-making about…

Methodology · Statistics 2023-08-14 X. M. Kavelaars , J. Mulder , M. C. Kaptein

Offline policy learning is aimed at learning decision-making policies using existing datasets of trajectories without collecting additional data. The primary motivation for using reinforcement learning (RL) instead of supervised learning…

Tie-breaker experimental designs are hybrids of Randomized Controlled Trials (RCTs) and Regression Discontinuity Designs (RDDs) in which subjects with moderate scores are placed in an RCT while subjects with extreme scores are…

Methodology · Statistics 2023-01-24 Dan M. Kluger , Art B. Owen

Epidemic propagation on networks represents an important departure from traditional massaction models. However, the high-dimensionality of the exact models poses a challenge to both mathematical analysis and parameter inference. By using…

Quantitative Methods · Quantitative Biology 2023-02-07 István Z. Kiss , Luc Berthouze , Wasiur R. KhudaBukhsh

Unmeasured confounding, unethical exposure, and ill-defined interventions pose significant challenges to evaluating policy-relevant mediation estimands in medicine and public health. In observational studies involving harmful exposures, the…

Methodology · Statistics 2026-05-12 Yang Bai , Yifan Cui , Baoluo Sun
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