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COVID-19, a viral respiratory pandemic, has rapidly spread throughout the globe. Large scale and rapid testing of the population is required to contain the disease, but such testing is prohibitive in terms of resources, cost and time.…

Populations and Evolution · Quantitative Biology 2020-07-21 Abhishek Srivastava , Anurag Mishra , Trusha Jayant Parekh , Sampreeti Jena

Suppressing SARS-CoV-2 will likely require the rapid identification and isolation of infected individuals, on an ongoing basis. RT-PCR (reverse transcription polymerase chain reaction) tests are accurate but costly, making regular testing…

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Tarun Jain , Bijendra Nath Jain

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

The corona virus disease 2019 (COVID-19) caused by the novel corona virus has an exponential rate of infection. COVID-19 is particularly notorious as the onset of symptoms in infected patients are usually delayed and there exists a large…

Methodology · Statistics 2020-04-16 Lakshmi N. Theagarajan

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

The group testing approach that achieves significant cost reduction over the individual testing approach has received a lot of interest lately for massive testing of COVID-19. Many studies simply assume samples mixed in a group are…

Methodology · Statistics 2021-11-12 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

CoVID-19 is currently one of the biggest threats to mankind. To date, it is the reason for infections of over 35 lakhs and the death of over 2 lakh human beings. We propose a procedure to detect CoVID-19 affected localities using a sewage…

Other Quantitative Biology · Quantitative Biology 2020-05-18 Ritam Guha , Anik Sengupta , Ankan Dutta

Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…

Quantitative Methods · Quantitative Biology 2020-04-08 Junan Zhu , Kristina Rivera , Dror Baron

The Reverse Transcription Polymerase Chain Reaction (RTPCR)} test is the silver bullet diagnostic test to discern COVID infection. Rapid antigen detection is a screening test to identify COVID positive patients in little as 15 minutes, but…

Machine Learning · Computer Science 2023-05-10 Md. Mohsin Sarker Raihan , Md. Mohi Uddin Khan , Laboni Akter , Abdullah Bin Shams

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

Physics and Society · Physics 2021-09-17 Surya Dheeshjith , Inavamsi Enaganti , Bud Mishra

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

The COVID-19 pandemic has had devastating effects on the well-being of the global population. The pandemic has been so prominent partly due to the high infection rate of the virus and its variants. In response, one of the most effective…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Jianxing Zhang , Pengcheng Xi , Ashkan Ebadi , Hilda Azimi , Stephane Tremblay , Alexander Wong

The rapid spread of COVID-19 and the emergence of new variants underscore the importance of effective screening measures. Rapid diagnosis and subsequent quarantine of infected individuals can prevent further spread of the virus in society.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Behzad Moayedi , Abdalsamad Keramatfar , Mohammad Hadi Goldani , Mohammad Javad Fallahi , Alborz Jahangirisisakht , Mohammad Saboori , Leyla badiei

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

Populations and Evolution · Quantitative Biology 2021-06-16 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

Quantitative Methods · Quantitative Biology 2022-08-31 Amit Solomon , Alejandro Cohen , Nir Shlezinger , Yonina C. Eldar , Muriel Médard

We propose a novel testing and containment strategy in order to contain the spread of SARS-CoV2 while permitting large parts of the population to resume social and economic activity. Our approach recognises the fact that testing capacities…

Populations and Evolution · Quantitative Biology 2020-04-29 Jakob Jonnerby , Philip Lazos , Edwin Lock , Francisco Marmolejo-Cossío , C. Bronk Ramsey , Meghana Shukla , Divya Sridhar

The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the world, leading to enormous amounts of human death and economic loss. Until definitive preventive or curative measures are developed, policies regarding testing,…

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

Populations and Evolution · Quantitative Biology 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou
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