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Accurate prediction and identification of variables associated with outcomes or disease states are critical for advancing diagnosis, prognosis, and precision medicine in biomedical research. Regularized regression techniques, such as lasso,…

Applications · Statistics 2025-04-14 Xiaoru Dong , Apoorva Goyal , Muxuan Liang , Maigan A. Brusko , Todd M. Brusko , Rhonda Bacher

We introduce HTAD, a novel model for diagnosis prediction using Electronic Health Records (EHR) represented as Heterogeneous Information Networks. Recent studies on modeling EHR have shown success in automatically learning representations…

Machine Learning · Computer Science 2019-12-24 Anahita Hosseini , Tyler Davis , Majid Sarrafzadeh

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

The objective of this study is to introduce methodology for studying longitudinal claims data observed at the patient level, with inference on the heterogeneity of healthcare utilization behaviors within large healthcare systems such as…

Applications · Statistics 2016-03-04 Ross P. Hilton , Nicoleta Serban , Richard Y. Zheng

The identification of phenotypes within complex diseases or syndromes is a fundamental component of precision medicine, which aims to adapt healthcare to individual patient characteristics. Postoperative delirium (POD) is a complex…

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

Methodology · Statistics 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Identifying subtle phenotypic variations in cellular images is critical for advancing biological research and accelerating drug discovery. These variations are often masked by the inherent cellular heterogeneity, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Anis Bourou , Biel Castaño Segade , Thomas Boyer , Valérie Mezger , Auguste Genovesio

We address the problem of using observational data to estimate peer contagion effects, the influence of treatments applied to individuals in a network on the outcomes of their neighbors. A main challenge to such estimation is that homophily…

Social and Information Networks · Computer Science 2022-05-18 Irina Cristali , Victor Veitch

Foundation models (e.g., CodeBERT, GraphCodeBERT, CodeT5) work well for many software engineering tasks. These models are pre-trained (using self-supervision) with billions of code tokens, and then fine-tuned with hundreds of thousands of…

Software Engineering · Computer Science 2022-06-03 Toufique Ahmed , Premkumar Devanbu

Clinician notes are a rich source of patient information but often contain inconsistencies due to varied writing styles, colloquialisms, abbreviations, medical jargon, grammatical errors, and non-standard formatting. These inconsistencies…

Computation and Language · Computer Science 2025-01-03 Daniel B. Hier , Michael D. Carrithers , Thanh Son Do , Tayo Obafemi-Ajayi

Understanding historical trends in the epidemic of HIV is important for assessing current and projecting future trends in prevalence, incidence and mortality and for evaluating the impact and cost-effectiveness of control measures. In…

Quantitative Methods · Quantitative Biology 2014-12-10 Brian G. Williams

Federated learning (FL) is increasingly adopted in domains like healthcare, where data privacy is paramount. A fundamental challenge in these systems is statistical heterogeneity-the fact that data distributions vary significantly across…

Machine Learning · Computer Science 2026-02-12 Zijian Wang , Xiaofei Zhang , Xin Zhang , Yukun Liu , Qiong Zhang

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

A broad spectrum of data from different modalities are generated in the healthcare domain every day, including scalar data (e.g., clinical measures collected at hospitals), tensor data (e.g., neuroimages analyzed by research institutes),…

Machine Learning · Computer Science 2018-03-28 Bokai Cao

Large scale databases with high-quality manual annotations are scarce in audio domain. We thus explore a self-supervised graph approach to learning audio representations from highly limited labelled data. Considering each audio sample as a…

Machine Learning · Computer Science 2022-11-23 Amir Shirian , Krishna Somandepalli , Tanaya Guha

Medication recommendation is a crucial task for assisting physicians in making timely decisions from longitudinal patient medical records. However, real-world EHR data present significant challenges due to the presence of rarely observed…

Artificial Intelligence · Computer Science 2025-08-15 Yan Ting Chok , Soyon Park , Seungheun Baek , Hajung Kim , Junhyun Lee , Jaewoo Kang

The most challenging, yet practical, setting of semi-supervised federated learning (SSFL) is where a few clients have fully labeled data whereas the other clients have fully unlabeled data. This is particularly common in healthcare settings…

Machine Learning · Computer Science 2023-10-31 Pramit Saha , Divyanshu Mishra , J. Alison Noble

This paper addresses the problem of matching pedestrians across multiple camera views, known as person re-identification. Variations in lighting conditions, environment and pose changes across camera views make re-identification a…

Computer Vision and Pattern Recognition · Computer Science 2015-12-01 Rahul Rama Varior , Gang Wang

Since federated learning (FL) has been introduced as a decentralized learning technique with privacy preservation, statistical heterogeneity of distributed data stays the main obstacle to achieve robust performance and stable convergence in…

Machine Learning · Computer Science 2022-12-08 Yanhang Shi , Siguang Chen , Haijun Zhang
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