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Computer simulations have become a very powerful tool for scientific research. Given the vast complexity that comes with many open scientific questions, a purely analytical or experimental approach is often not viable. For example,…

Neural and Evolutionary Computing · Computer Science 2016-07-12 Roman Bauer , Lukas Breitwieser , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Max Talanov

Data distribution across different facilities offers benefits such as enhanced resource utilization, increased resilience through replication, and improved performance by processing data near its source. However, managing such data is…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-02 Dante D. Sanchez-Gallegos , J. L. Gonzalez-Compean , Maxime Gonthier , Valerie Hayot-Sasson , J. Gregory Pauloski , Haochen Pan , Kyle Chard , Jesus Carretero , Ian Foster

We describe the current state and future plans for a set of tools for scientific data management (SDM) designed to support scientific transparency and reproducible research. SDM has been in active use at our MRI Center for more than two…

Quantitative Methods · Quantitative Biology 2015-02-25 B. A. Wandell , A. Rokem , L. M. Perry , G. Schaefer , R. F. Dougherty

Many scientific applications are I/O intensive and generate or access large data sets, spanning hundreds or thousands of "files." Management, storage, efficient access, and analysis of this data present an extremely challenging task. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Jaechun No , Rajeev Thakur , Dinesh Kaushik , Lori Freitag , Alok Choudhary

Computer simulations have become a very powerful tool for scientific research. In order to facilitate research in computational biology, the BioDynaMo project aims at a general platform for biological computer simulations, which should be…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-18 Lukas Breitwieser , Roman Bauer , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Fons Rademakers , Max Talanov

The globally distributed computing infrastructure required to cope with the multi-petabytes datasets produced by the Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) at CERN comprises several subsystems, such as…

Software Engineering · Computer Science 2020-07-08 Christian Ariza-Porras , Valentin Kuznetsov , Federica Legger

Rucio is an open-source software framework that provides scientific collaborations with the functionality to organize, manage, and access their data at scale. The data can be distributed across heterogeneous data centers at widely…

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

Scientific applications produce a huge amount of data, which imposes serious management and analysis challenges. In particular, limitations in current database management systems prevent their adoption in simulation applications, in which…

Databases · Computer Science 2019-03-18 Hermano Lustosa , Fabio Porto

Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-08 Alessandro Margara , Gianpaolo Cugola , Nicolò Felicioni , Stefano Cilloni

We present DISco, a storage and communication middleware designed to enable distributed and task-centric autonomic control of networks. DISco is designed to enable multi-agent identification of anomalous situations -- so-called "challenges"…

Networking and Internet Architecture · Computer Science 2015-03-20 Sylvain Martin , Laurent Chiarello , Guy Leduc

Advances in technology and computing hardware are enabling scientists from all areas of science to produce massive amounts of data using large-scale simulations or observational facilities. In this era of data deluge, effective coordination…

Databases · Computer Science 2015-03-31 Spyros Blanas , Surendra Byna

Today's astronomical projects need computational systems capable to store and analyze large amounts of scientific data, to effectively share data with other research Institutes and to easily implement information services to present data…

Astrophysics · Physics 2007-05-23 G. Calderone , L. Nicastro

The ability to collect and analyze large amounts of data is a growing problem within the scientific community. The growing gap between data and users calls for innovative tools that address the challenges faced by big data volume, velocity…

The increasingly collaborative, globalized nature of scientific research combined with the need to share data and the explosion in data volumes present an urgent need for a scientific data management system (SDMS). An SDMS presents a…

Databases · Computer Science 2020-04-09 Dale Stansberry , Suhas Somnath , Jessica Breet , Gregory Shutt , Mallikarjun Shankar

This paper is a brief update on developments in the BioDynaMo project, a new platform for computer simulations for biological research. We will discuss the new capabilities of the simulator, important new concepts simulation methodology as…

Neural and Evolutionary Computing · Computer Science 2018-01-22 Leonard Johard , Lukas Breitwieser , Alberto Di Meglio , Marco Manca , Manuel Mazzara , Max Talanov

In the era of data-driven science, conducting computational experiments that involve analysing large datasets using heterogeneous computational clusters, is part of the everyday routine for many scientists. Moreover, to ensure the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-23 Thanasis Vergoulis , Konstantinos Zagganas , Loukas Kavouras , Martin Reczko , Stelios Sartzetakis , Theodore Dalamagas

Leadership computing facilities around the world support cutting-edge scientific research across a broad spectrum of disciplines including understanding climate change, combating opioid addiction, or simulating the decay of a neutron. While…

High Energy Physics - Lattice · Physics 2020-04-16 Chia Cheng Chang , Christopher Körber , André Walker-Loud

As quantum computing advances towards practical applications, quantum operating systems become inevitable, where multi-programming -- the core functionality of operating systems -- enables concurrent execution of multiple quantum programs…

Quantum Physics · Physics 2025-07-08 Wenjie Sun , Xiaoyu Li , Zhigang Wang , Geng Chen , Lianhui Yu , Guowu Yang

Data intensive applications often involve the analysis of large datasets that require large amounts of compute and storage resources. While dedicated compute and/or storage farms offer good task/data throughput, they suffer low resource…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-08-27 Ioan Raicu , Yong Zhao , Ian Foster , Alex Szalay
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