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Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with $n$ alterations, and how long will…

Populations and Evolution · Quantitative Biology 2023-07-07 Michael D. Nicholson , David Cheek , Tibor Antal

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

In their 2006 seminal paper in Distributed Computing, Angluin et al. present a construction that, given any Presburger predicate as input, outputs a leaderless population protocol that decides the predicate. The protocol for a predicate of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-31 Philipp Czerner , Roland Guttenberg , Martin Helfrich , Javier Esparza

The stochastic simulation of biological systems is an increasingly popular technique in bioinformatics. It often is an enlightening technique, which may however result in being computational expensive. We discuss the main opportunities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Marco Aldinucci , Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Massimo Torquati , Angelo Troina

Distributed algorithms and theories are called for in this era of big data. Under weaker local signal-to-noise ratios, we improve upon the celebrated one-round distributed principal component analysis (PCA) algorithm designed in the spirit…

Methodology · Statistics 2025-07-01 ZeYu Li , Xinsheng Zhang , Wang Zhou

We consider a broad class of continuous-time two-type population size-dependent Markov Branching Processes. The offspring distribution can depend on the current (alive) and total (dead and alive) populations. Using stochastic approximation…

Probability · Mathematics 2023-04-04 Khushboo Agarwal , Veeraruna Kavitha

Population protocols are a well-studied model of distributed computation in which a group of anonymous finite-state agents communicates via pairwise interactions. Together they decide whether their initial configuration, that is, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-03 Steffen van Bergerem , Roland Guttenberg , Sandra Kiefer , Corto Mascle , Nicolas Waldburger , Chana Weil-Kennedy

Upcoming many core processors are expected to employ a distributed memory architecture similar to currently available supercomputers, but parallel pattern mining algorithms amenable to the architecture are not comprehensively studied. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-10-28 Kazuki Yoshizoe , Aika Terada , Koji Tsuda

The abundance of predicted and mined but uncertain biological data show huge needs for massive, efficient and scalable curation efforts. The human expertise warranted by any successful curation enterprize is often economically prohibitive…

Databases · Computer Science 2016-06-08 Hasan M. Jamil , Fereidoon Sadri

We present efficient and practical algorithms for a large, distributed system of processors to achieve reliable computations in a secure manner. Specifically, we address the problem of computing a general function of several private inputs…

Cryptography and Security · Computer Science 2021-01-29 Donald Rozinak Beaver

Distributed Constraint Optimization Problems (DCOPs) are a widely studied class of optimization problems in which interaction between a set of cooperative agents are modeled as a set of constraints. DCOPs are NP-hard and significant effort…

Artificial Intelligence · Computer Science 2020-09-04 Saaduddin Mahmud , Md. Mosaddek Khan , Nicholas R. Jennings

The inference of Neural Networks is usually restricted by the resources (e.g., computing power, memory, bandwidth) on edge devices. In addition to improving the hardware design and deploying efficient models, it is possible to aggregate the…

Machine Learning · Computer Science 2021-11-05 Jun-Liang Lin , Sheng-De Wang

We initiate the study of graph algorithms in the streaming setting on massive distributed and parallel systems inspired by practical data processing systems. The objective is to design algorithms that can efficiently process evolving graphs…

Data Structures and Algorithms · Computer Science 2025-01-20 Artur Czumaj , Gopinath Mishra , Anish Mukherjee

The paper investigates the distributed estimation problem under low bit rate communications. Based on the signal-comparison (SC) consensus protocol under binary-valued communications, a new consensus+innovations type distributed estimation…

Systems and Control · Electrical Eng. & Systems 2025-03-25 Jieming Ke , Xiaodong Lu , Yanlong Zhao , Ji-Feng Zhang

Generative Modelling has become a promising use case for near term quantum computers. In particular, due to the fundamentally probabilistic nature of quantum mechanics, quantum computers naturally model and learn probability distributions,…

Quantum Physics · Physics 2022-12-29 Ieva Čepaitė , Brian Coyle , Elham Kashefi

We consider the problem of distributed learning, where a network of agents collectively aim to agree on a hypothesis that best explains a set of distributed observations of conditionally independent random processes. We propose a…

Optimization and Control · Mathematics 2017-04-12 Angelia Nedić , Alex Olshevsky , César A. Uribe

Biological cells replicate their genomes in a well-planned manner. The DNA replication program of an organism determines the timing at which different genomic regions are replicated, with fundamental consequences for cell homeostasis and…

Subcellular Processes · Quantitative Biology 2024-05-28 Florian Pflug , Deepak Bhat , Simone Pigolotti

In this paper, we propose a cognitive protocol that involves cooperation between the primary and secondary users. In addition to its own queue, the secondary user (SU) has a queue to store, and then relay, the undelivered primary packets.…

Networking and Internet Architecture · Computer Science 2014-07-10 Ahmed El Shafie , Ahmed Sultan , Tamer Khattab

The problem of distributed function computation is studied, where functions to be computed is not necessarily symbol-wise. A new method to derive a converse bound for distributed computing is proposed; from the structure of functions to be…

Information Theory · Computer Science 2017-07-10 Shigeaki Kuzuoka , Shun Watanabe

Population-based learning paradigms, including evolutionary strategies, Population-Based Training (PBT), and recent model-merging methods, combine fast within-model optimisation with slower population-level adaptation. Despite their…

Machine Learning · Computer Science 2026-03-26 Giacomo Borghi , Hyesung Im , Lorenzo Pareschi