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Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

We introduce a region-specific diffeomorphic metric mapping (RDMM) registration approach. RDMM is non-parametric, estimating spatio-temporal velocity fields which parameterize the sought-for spatial transformation. Regularization of these…

Computer Vision and Pattern Recognition · Computer Science 2019-11-12 Zhengyang Shen , François-Xavier Vialard , Marc Niethammer

Regularization strategies in medical image registration often take a one-size-fits-all approach by imposing uniform constraints across the entire image domain. Yet biological structures are anything but regular. Lacking structural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Ziad Kheil , Soleakhena Ken , Laurent Risser

Unsupervised image registration commonly adopts U-Net style networks to predict dense displacement fields in the full-resolution spatial domain. For high-resolution volumetric image data, this process is however resource-intensive and…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Xi Jia , Joseph Bartlett , Wei Chen , Siyang Song , Tianyang Zhang , Xinxing Cheng , Wenqi Lu , Zhaowen Qiu , Jinming Duan

Deformable image registration is a fundamental problem in the field of medical image analysis. During the last years, we have witnessed the advent of deep learning-based image registration methods which achieve state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Lucas Mansilla , Diego H. Milone , Enzo Ferrante

We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Julian Krebs , Tommaso Mansi , Boris Mailhé , Nicholas Ayache , Hervé Delingette

We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross…

Computer Vision and Pattern Recognition · Computer Science 2021-09-02 Sergiu Mocanu , Alan R. Moody , April Khademi

Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Xiaoyue Zhang , Weijian Jian , Yu Chen , Shihting Yang

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

This paper presents NimbleReg, a light-weight deep-learning (DL) framework for diffeomorphic image registration leveraging surface representation of multiple segmented anatomical regions. Deep learning has revolutionized image registration…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Antoine Legouhy , Ross Callaghan , Nolah Mazet , Vivien Julienne , Hojjat Azadbakht , Hui Zhang

Image-based rigid 2D/3D registration is a critical technique for fluoroscopic guided surgical interventions. In recent years, some learning-based fully differentiable methods have produced beneficial outcomes while the process of feature…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Minheng Chen , Zhirun Zhang , Shuheng Gu , Zhangyang Ge , Youyong Kong

Recently, convolutional neural networks (CNN) have been successfully applied to many remote sensing problems. However, deep learning techniques for multi-image super-resolution from multitemporal unregistered imagery have received little…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Andrea Bordone Molini , Diego Valsesia , Giulia Fracastoro , Enrico Magli

Image registration plays an important role in comparing images. It is particularly important in analyzing medical images like CT, MRI, PET, etc. to quantify different biological samples, to monitor disease progression and to fuse different…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Though, deep learning based medical image registration is currently starting to show promising advances, often, it still fells behind conventional frameworks in terms of registration accuracy. This is especially true for applications where…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Lasse Hansen , Mattias P. Heinrich

This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were…

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson

We introduce an end-to-end deep-learning framework for 3D medical image registration. In contrast to existing approaches, our framework combines two registration methods: an affine registration and a vector momentum-parameterized stationary…

Computer Vision and Pattern Recognition · Computer Science 2019-03-22 Zhengyang Shen , Xu Han , Zhenlin Xu , Marc Niethammer

Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Rohit Jena , Pratik Chaudhari , James C. Gee

Deformable registration of two-dimensional/three-dimensional (2D/3D) images of abdominal organs is a complicated task because the abdominal organs deform significantly and their contours are not detected in two-dimensional X-ray images. We…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Ryuto Miura , Megumi Nakao , Mitsuhiro Nakamura , Tetsuya Matsuda

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan