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Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Abdulqader Mohammed , Mohammed Abdel Razek , Mohamed El-dosuky , Ahmed Sobhi

Tumor cells with two nuclei (binucleated cells, BiNC) or more nuclei (multinucleated cells, MuNC) indicate an increased amount of cellular genetic material which is thought to facilitate oncogenesis, tumor progression and treatment…

Mitotic figure detection in histopathology images remains challenging due to significant domain shifts across different scanners, staining protocols, and tissue types. This paper presents our approach for the MIDOG 2025 challenge Track 1,…

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Breast density estimation is one of the key tasks in recognizing individuals predisposed to breast cancer. It is often challenging because of low contrast and fluctuations in mammograms' fatty tissue background. Most of the time, the breast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Vikash Gupta , Mutlu Demirer , Robert W. Maxwell , Richard D. White , Barbaros Selnur Erdal

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

The effective localization of mitosis is a critical precursory task for deciding tumor prognosis and grade. Automated mitosis detection through deep learning-oriented image analysis often fails on unseen patient data due to inherent domain…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Tirupati Saketh Chandr , Sahar Almahfouz Nasser , Nikhil Cherian Kurian , Amit Sethi

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…

Medical Physics · Physics 2025-05-16 Ashmit K Mishra , Mousa Alrubayan , Prabhakar Pradhan

Mitotic count is the most important morphological feature of breast cancer grading. Many deep learning-based methods have been proposed but suffer from domain shift. In this work, we construct a Fourier-based segmentation model for mitosis…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sen Yang , Feng Luo , Jun Zhang , Xiyue Wang

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

Breast cancer is prevalent in Ethiopia that accounts 34% among women cancer patients. The diagnosis technique in Ethiopia is manual which was proven to be tedious, subjective, and challenging. Deep learning techniques are revolutionizing…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Simon Hadush , Yaecob Girmay , Abiot Sinamo , Gebrekirstos Hagos

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

The attributes of object contours has great significance for instance segmentation task. However, most of the current popular deep neural networks do not pay much attention to the object edge information. Inspired by the human annotation…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Wenchao Zhang , Chong Fu , Mai Zhu

Objective: To develop an automatic image normalization algorithm for intensity correction of images from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) acquired by different MRI scanners with various imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Jun Zhang , Ashirbani Saha , Brian J. Soher , Maciej A. Mazurowski

Breast cancer is a common fatal disease for women. Early diagnosis and detection is necessary in order to improve the prognosis of breast cancer affected people. For predicting breast cancer, several automated systems are already developed…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal

Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing…

Image and Video Processing · Electrical Eng. & Systems 2021-01-22 David Joon Ho , Dig V. K. Yarlagadda , Timothy M. D'Alfonso , Matthew G. Hanna , Anne Grabenstetter , Peter Ntiamoah , Edi Brogi , Lee K. Tan , Thomas J. Fuchs

Skin cancer is a life-threatening disease where early detection significantly improves patient outcomes. Automated diagnosis from dermoscopic images is challenging due to high intra-class variability and subtle inter-class differences. Many…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Md. Enamul Atiq , Shaikh Anowarul Fattah

Deep learning has driven significant advances in mitotic figure analysis within computational pathology. In this paper, we present our approach to the Mitosis Domain Generalization (MIDOG) 2025 Challenge, which consists of two distinct…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Shuting Xu , Runtong Liu , Zhixuan Chen , Junlin Hou , Hao Chen

Breast cancer is the second most common cancer among women worldwide. Diagnosis of breast cancer by the pathologists is a time-consuming procedure and subjective. Computer aided diagnosis frameworks are utilized to relieve pathologist…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Bahareh Morovati , Reza Lashgari , Mojtaba Hajihasani , Hasti Shabani