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Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Siddhant Rao

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Robin Elizabeth Yancey

Accurate detection of mitosis plays a critical role in breast cancer histopathology. Manual detection and counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Multispectral imaging is a recent…

Computer Vision and Pattern Recognition · Computer Science 2013-04-16 H. Irshad , A. Gouaillard , L. Roux , D. Racoceanu

Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Marc Aubreville , Jonathan Ganz , Jonas Ammeling , Taryn A. Donovan , Rutger H. J. Fick , Katharina Breininger , Christof A. Bertram

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Alexander Rakhlin , Alexey Shvets , Vladimir Iglovikov , Alexandr A. Kalinin

Deep learning object detection algorithm has been widely used in medical image analysis. Currently all the object detection tasks are based on the data annotated with object classes and their bounding boxes. On the other hand, medical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Li Xiao , Cheng Zhu , Junjun Liu , Chunlong Luo , Peifang Liu , Yi Zhao

This is the submission for mitosis detection in the context of the MIDOG 2021 challenge. It is based on the two-stage objection model Faster RCNN as well as DenseNet as a backbone for the neural network architecture. It achieves a F1-score…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Michel Halmes , Hippolyte Heuberger , Sylvain Berlemont

In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Ruiwen Ding , James Hall , Neil Tenenholtz , Kristen Severson

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Neil Chaudhary , Zaynah Dhunny

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Mostafa Jahanifar , Adam Shephard , Neda Zamanitajeddin , Simon Graham , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

One of the methods for stratifying different molecular classes of breast cancer is the Nottingham Prognostic Index Plus (NPI+) which uses breast cancer relevant biomarkers to stain tumour tissues prepared on tissue microarray (TMA). To…

Computer Vision and Pattern Recognition · Computer Science 2019-01-15 Jingxin Liu , Bolei Xu , Chi Zheng , Yuanhao Gong , Jon Garibaldi , Daniele Soria , Andew Green , Ian O. Ellis , Wenbin Zou , Guoping Qiu

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Chen Yang , Wang Ziyue , Fang Zijie , Bian Hao , Zhang Yongbing

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Automatic segmentation of microscopy images is an important task in medical image processing and analysis. Nucleus detection is an important example of this task. Mask-RCNN is a recently proposed state-of-the-art algorithm for object…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Jeremiah W. Johnson
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