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Experiments of cell migration and chemotaxis assays have been classically performed in the so-called Boyden Chambers. A recent technology, xCELLigence Real Time Cell Analysis, is now allowing to monitor the cell migration in real time. This…

We study a chemotaxis system that includes two competitive prey and one predator species in a two-dimensional domain, where the movement of prey (resp. predators) is driven by chemicals secreted by predators (resp. prey), called mutually…

Analysis of PDEs · Mathematics 2025-08-19 Cordula Reisch , Bao-Ngoc Tran , Juan Yang

Tumor cells invade individually or in groups, mediated by mechanical interactions between cells and their surrounding matrix. These multicellular dynamics are reminiscent of leader-follower coordination and epithelial-mesenchymal…

Cell Behavior · Quantitative Biology 2022-06-28 Alex M. Hruska , Haiqian Yang , Susan E. Leggett , Ming Guo , Ian Y. Wong

We consider an evolutionary PDE system coupling the Cahn-Hilliard equation with singular potential, mass source and transport effects, to a Brinkman-type relation for the macroscopic velocity field and to a further equation describing the…

Analysis of PDEs · Mathematics 2024-11-20 Giulio Schimperna

In this paper we consider a biased velocity jump process with excluded-volume interactions for chemotaxis, where we account for the size of each particle. Starting with a system of N individual hard rod particles in one dimension, we derive…

Biological Physics · Physics 2020-03-04 Tertius Ralph , Stephen W. Taylor , Maria Bruna

Direct detection experiments aim at the detection of dark matter in the form of weakly interacting massive particles (WIMPs) by searching for signals from elastic dark matter nucleus scattering. Additionally, inelastic scattering in which…

High Energy Physics - Phenomenology · Physics 2020-01-08 G. Arcadi , C. Döring , C. Hasterok , S. Vogl

Cell-to-cell variability is inherent to numerous biological processes, including cell migration. Quantifying and characterizing the variability of migrating cells is challenging, as it requires monitoring many cells for long time windows…

Biological Physics · Physics 2021-05-06 David B. Brückner , Alexandra Fink , Joachim O. Rädler , Chase P. Broedersz

Directed fibroblast migration is central to highly proliferative processes in regenerative medicine and developmental biology, such as wound healing and embryogenesis. However, the mechanisms by which single fibroblasts affect each other's…

Cell Behavior · Quantitative Biology 2018-08-29 Q. L. Pham , D. Chege , T. Dijamco , J. Brito , E. Stein , N. A. N. Tong , S. Basuray , R. S. Voronov

The structure of DNA Binding Proteins enables a strong interaction with their specific target site on DNA. However, recent single molecule experiment reported that proteins can diffuse on DNA. This suggests that the interactions between…

Biomolecules · Quantitative Biology 2015-05-13 Vincent Dahirel , Fabien Paillusson , Marie Jardat , Maria Barbi , Jean-Marc Victor

This study introduces a nonparametric definition of interaction and provides an approach to both interaction discovery and efficient estimation of this parameter. Using stochastic shift interventions and ensemble machine learning, our…

Methodology · Statistics 2024-07-01 David B. McCoy , Alan E. Hubbard , Alejandro Schuler , Mark J. van der Laan

Visual relationship detection aims to detect the interactions between objects in an image; however, this task suffers from combinatorial explosion due to the variety of objects and interactions. Since the interactions associated with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Yue Hu , Siheng Chen , Xu Chen , Ya Zhang , Xiao Gu

Chemotactic interactions are ubiquitous in nature and can lead to nonreciprocal and complex emergent behavior in multibody systems. Here we show how chemotactic signaling between microscale oil droplets of different chemistries in micellar…

The purpose of this work is the study of \textit{chemotaxis} and how to model it through the equations of Keller-Segel. \textit{Chemotaxis} is a natural process which induces the organisms to direct their movement according to certain…

Analysis of PDEs · Mathematics 2021-11-24 Alejandro Fernández-Jiménez

Chemotaxis systems play a crucial role in modeling the dynamics of bacterial and cellular behaviors, including propagation, aggregation, and pattern formation, all under the influence of chemical signals. One notable characteristic of these…

Numerical Analysis · Mathematics 2024-02-07 Alina Chertock , Shumo Cui , Alexander Kurganov , Chenxi Wang

Phototaxis is an important reaction to light displayed by a wide range of motile microorganisms. Flagellated eukaryotic microalgae in particular, like the model organism Chlamydomonas reinhardtii, steer either towards or away from light by…

Cell Behavior · Quantitative Biology 2016-11-28 Jorge Arrieta , Ana Barreira , Maurizio Chioccioli , Marco Polin , Idan Tuval

Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

Biological Physics · Physics 2023-10-10 David B. Brückner , Chase P. Broedersz

To survive in ever-changing environments, living organisms need to continuously combine the ongoing external inputs they receive, representing present conditions, with their dynamical internal state, which includes influences of past…

Neurons and Cognition · Quantitative Biology 2024-02-09 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

We consider a continuous mathematical description of a population of ants and simulate numerically their foraging behavior using a system of partial differential equations of chemotaxis type. We show that this system accurately reproduces…

Adaptation and Self-Organizing Systems · Physics 2015-10-26 Paulo Amorim

Active matter systems comprise self-propelled particles that move on a substrate while leaving chemical trails that influence other particles through chemotaxis (e.g., slime-depositing bacteria). Orientational chemotaxis manifests as a…

Soft Condensed Matter · Physics 2025-12-11 Aymeric Lutier , Frédéric van Wijland , Jean-Baptiste Fournier

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

Cell Behavior · Quantitative Biology 2026-02-24 Martina Conte , Romina Travaglini
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