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Data scarcity is a common obstacle in medical research due to the high costs associated with data collection and the complexity of gaining access to and utilizing data. Synthesizing health data may provide an efficient and cost-effective…

Machine Learning · Computer Science 2023-08-01 Arinbjörn Kolbeinsson , Luca Foschini

Electronic health record (EHR) management systems require the adoption of effective technologies when health information is being exchanged. Current management approaches often face risks that may expose medical record storage solutions to…

Cryptography and Security · Computer Science 2021-01-28 Charalampos Stamatellis , Pavlos Papadopoulos , Nikolaos Pitropakis , Sokratis Katsikas , William J Buchanan

Electronic Health Records (EHRs) exhibit a high amount of missing data due to variations of patient conditions and treatment needs. Imputation of missing values has been considered an effective approach to deal with this challenge. Existing…

Machine Learning · Computer Science 2022-10-25 Yuxi Liu , Shaowen Qin , Zhenhao Zhang , Wei Shao

Electronic Health Records (EHRs) hold immense potential for advancing healthcare, offering rich, longitudinal data that combines structured information with valuable insights from unstructured clinical notes. However, the unstructured…

Computation and Language · Computer Science 2025-01-31 Huaiyuan Ying , Hongyi Yuan , Jinsen Lu , Zitian Qu , Yang Zhao , Zhengyun Zhao , Isaac Kohane , Tianxi Cai , Sheng Yu

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

Sharing data from clinical studies can facilitate innovative data-driven research and ultimately lead to better public health. However, sharing biomedical data can put sensitive personal information at risk. This is usually solved by…

The effective analysis of high-dimensional Electronic Health Record (EHR) data, with substantial potential for healthcare research, presents notable methodological challenges. Employing predictive modeling guided by a knowledge graph (KG),…

Methodology · Statistics 2025-11-06 Zhiwei Xu , Ziming Gan , Doudou Zhou , Shuting Shen , Junwei Lu , Tianxi Cai

Generative Artificial Intelligence (GenAI), particularly Large Language Models (LLMs), offer powerful capabilities for interpreting the complex data landscape in healthcare. In this paper, we present a comprehensive overview of the…

Machine Learning · Computer Science 2025-09-05 Ankit Shetgaonkar , Dipen Pradhan , Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj

Foundation models trained on large-scale de-identified electronic health records (EHRs) hold promise for clinical applications. However, their capacity to memorize patient information raises important privacy concerns. In this work, we…

Machine Learning · Computer Science 2025-10-16 Sana Tonekaboni , Lena Stempfle , Adibvafa Fallahpour , Walter Gerych , Marzyeh Ghassemi

Electrocardiogram (ECG) is a widely used non-invasive diagnostic tool for heart diseases. Many studies have devised ECG analysis models (e.g., classifiers) to assist diagnosis. As an upstream task, researches have built generative models to…

Machine Learning · Computer Science 2023-05-30 Jintai Chen , Kuanlun Liao , Kun Wei , Haochao Ying , Danny Z. Chen , Jian Wu

The extraction of phenotype information which is naturally contained in electronic health records (EHRs) has been found to be useful in various clinical informatics applications such as disease diagnosis. However, due to imprecise…

Computation and Language · Computer Science 2019-11-12 Jingqing Zhang , Xiaoyu Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

In this paper, we propose a data privacy-preserving and communication efficient distributed GAN learning framework named Distributed Asynchronized Discriminator GAN (AsynDGAN). Our proposed framework aims to train a central generator learns…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Qi Chang , Hui Qu , Yikai Zhang , Mert Sabuncu , Chao Chen , Tong Zhang , Dimitris Metaxas

Existing approaches to protect the privacy of Electronic Health Records are either insufficient for existing medical laws or they are too restrictive in their usage. For example, smart card-based encryption systems require the patient to be…

Cryptography and Security · Computer Science 2015-06-12 Adebayo Omotosho , Omotanwa Adegbola , Barakat Adelakin , Adeyemi Adelakun , Justice Emuoyibofarhe

Electronic Medical Records (EHR) are extremely sparse. Only a small proportion of events (symptoms, diagnoses, and treatments) are observed in the lifetime of an individual. The high degree of missingness of EHR can be attributed to a large…

Artificial Intelligence · Computer Science 2021-11-18 Ramon Vinas , Xu Zheng , Jer Hayes

Generative Adversarial Networks (GANs) have made releasing of synthetic images a viable approach to share data without releasing the original dataset. It has been shown that such synthetic data can be used for a variety of downstream tasks…

Machine Learning · Computer Science 2020-12-15 Sumit Mukherjee , Yixi Xu , Anusua Trivedi , Juan Lavista Ferres

Electronic Health Records (EHRs) provide a wealth of information for machine learning algorithms to predict the patient outcome from the data including diagnostic information, vital signals, lab tests, drug administration, and demographic…

Machine Learning · Computer Science 2021-06-16 Byunggill Joe , Akshay Mehra , Insik Shin , Jihun Hamm

Federated learning (FL) is the most practical multi-source learning method for electronic healthcare records (EHR). Despite its guarantee of privacy protection, the wide application of FL is restricted by two large challenges: the…

Machine Learning · Computer Science 2022-11-15 Junu Kim , Kyunghoon Hur , Seongjun Yang , Edward Choi

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Despite the remarkable progress in the development of predictive models for healthcare, applying these algorithms on a large scale has been challenging. Algorithms trained on a particular task, based on specific data formats available in a…

Machine Learning · Computer Science 2023-11-16 Kyunghoon Hur , Jungwoo Oh , Junu Kim , Jiyoun Kim , Min Jae Lee , Eunbyeol Cho , Seong-Eun Moon , Young-Hak Kim , Louis Atallah , Edward Choi

As a revolutionary generative paradigm of deep learning, generative adversarial networks (GANs) have been widely applied in various fields to synthesize realistic data. However, it is challenging for conventional GANs to synthesize raw…

Signal Processing · Electrical Eng. & Systems 2023-06-27 Weidong Wang , Jiancheng An , Hongshu Liao , Lu Gan , Chau Yuen
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